Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Celiac.com!
    eNewsletter
    Donate

How Do You Get Celiac

Guest gliX

Recommended Posts

Guest gliX
Guest gliX
Posted

I learned I had celiac 2 years ago and have been gluten-free since. Does that mean I was born with the disease? No one in my immediate family tested positive for celiac, except my aunt and most of my cousins recently tested positive. We suspect my grandpa might've had it but don't want to test him for it at this time, he is 90 and very weak. Can celiac be given from one person to another other than through genes. If so, how exactly? Can it be given through physical contact? Thanks.

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


KaitiUSA Enthusiast
KaitiUSA
Posted

Celiac disease is not contagious and can not be given to anyone through contact, kissing, etc.... You are born with the predisposition and genes for it but it may not be activated until something triggers it later in life. If there are family members who have it that shows it runs in the family. It is a genetic autoimmune disease. It can be triggered at any point in life. I was always healthy growing up then mono triggered my celiac. Celiac can be triggered by surgeries,stress, childbirth, viruses such as mono, and so forth. There is a small percentage of people without the gene.

Link to comment
Share on other sites
Carriefaith Enthusiast
Carriefaith
Posted

Most people that have the gene for celiac are either born with celiac or they get it later in life. For those who get it later in life, I think the gene stays off until an environmental or physical stress triggers the gene on, resulting in celiac. I think there is a small percent of people that get celiac without the gene.

Celiac is not a virus or a bacterial infection, therefore, you cannot "catch" it. However, you can pass it on to your kids through your genes.

Link to comment
Share on other sites
celiac3270 Collaborator
celiac3270
Posted

Yes...Celiac cannot be given to anyone else, except of course, through genes. You didn't necessarily have celiac a birth, but you had a genetic predisposition to it...HLA DQ2 and DQ8....then the celiac had to be triggered, such as with surgery or high-stress situations. Once triggered, of course, you have it. Of course, triggers aren't contained to a high-stress situation, surgery, etc.....

The fact that you have it means that someone else in your family had it before you. It could be a parent, it could be a grandparent on either side of your family, or even one of their parents....

Link to comment
Share on other sites
Guest gliX
Guest gliX
Posted

Oh, I didn't think it could be sent through physical contact, just curious. Has gene therapy successfully been used to this point to cure celiac disease? (by correcting or replacing the gene that triggers celiec disease)

Link to comment
Share on other sites
MySuicidalTurtle Enthusiast
MySuicidalTurtle
Posted

Isn't it the symptoms which the triggers bring out?

Link to comment
Share on other sites
KaitiUSA Enthusiast
KaitiUSA
Posted

It can trigger symptoms to start but it doesn't have to. Some people just don't get symptoms.

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


MySuicidalTurtle Enthusiast
MySuicidalTurtle
Posted

Right, that's why I think all of us are born with it and then we see the symptoms.

Link to comment
Share on other sites
Lesliean Apprentice
Lesliean
Posted

I always wonder when they say some people get Celiac disease who don't have the genes because there are documented cases, around 2%, who have HLA DQ1 or DQ3. While those with DQ1 and DQ3 generally present with neurological symptoms and often gastro symptoms, they often flunk the gold standard biopsy test. (If you look at gluten ataxia which is resolved with a gluten free diet and has positive serology for anti-glaindins, DQ2 is 70%, DQ8 is 10%, and DQ1 is 20% so there are a lot of gluten sensitive people out there who need to be on a gfd who are not DQ2 or 8).

So, I think we can pretty well trace all Celiac disease back to a genetic predisposition of DQ2 of 90%, DQ8 of 8%, and DQ1 of 2% and sometimes DQ3. If we take away the biopsy for the diagnosis and use gluten relieved symptoms and positive serology instead the numbers go way up and include more DQ 1 nd 3. I know I've had it all my life and I carry two copies of DQ1. Others have symptoms as children and it goes away till adulthood and others are triggered by a trauma, but all have the genetic markers for it. It even seems the symptoms you tend to get are most often typical of the genetic makeup you have. DQ2 and 8 are very sensitive gastro markers and 1 often is gluten ataxia, and 3 has its particular tendencies, and so on. This is cutting edge science.

brain.hastypastry.net has a posting for a immunization that may be coming out but their board is down right now so I can't add the link. Will try to add it tomorrow.

Leslie

Link to comment
Share on other sites
Guest gliX
Guest gliX
Posted

What exactly would an immunization do? Is this a cure for the disease?

Link to comment
Share on other sites
KaitiUSA Enthusiast
KaitiUSA
Posted

There is no cure for the disease as of now and there won't be one for a while. They are only in researching stages for things. The only thing is the gluten free diet.

Link to comment
Share on other sites
ianm Apprentice
ianm
Posted

A pill or an immunization for this disease is just not the way to go. It is much better to live a healthy lifestyle. A drug just so I can eat crap is just plain wrong. At the risk of sounding like a consipiracy theorist a drug to cure this disease is not going to do you any good. All it will do is cover up the symptoms not treat the source of the disease. This way Pfizer gets rich because you buy their pill so you can eat ConAgra's genetically engineered crap :o . Not a good thing at all :angry: .

Link to comment
Share on other sites
Lesliean Apprentice
Lesliean
Posted

Kaiti is right, the GFD is the only cure and I didn't mean to imply otherwise. I shouldn't be allowed to use a computere after 10PM! Still can't get the brain.hastypastry.net to open so I'll let you know what this far off dream note says when I get a chance to copy it over for you.

I'm just glad there is a cure-the diet- and that I am not taking a medicine with side effects for the rest of my life.

PS-Even my asthma is going away now that I am gluten-free. Wow.

Leslie

Link to comment
Share on other sites
skbird Contributor
skbird
Posted

I'm with Ianm on this one - I guess the only benefit I can see is for the "oops!" factor (accidental glutening) but then again as lazy as most people are (myself included) if I didn't react anymore I'd probably eat a lot more junk. Though at this point I may be selling myself short, I have been eating great food for 3 years now and loving it! When people ask me how I can stand going to three different stores for groceries, spending extra money, etc, I say hey, this is my life-long hobby and I LOVE it! :)

And as you can see in my signature, I'm a DQ1/DQ3 so maybe I don't have true Celiac but I'm definitely paying for having an "oops" this last weekend... :( Hopefully it will be over soon...

Stephanie

Link to comment
Share on other sites
KaitiUSA Enthusiast
KaitiUSA
Posted

I do agree with Ian....the gluten free diet is just a healthier and better way to go even when they discover something years off.

Link to comment
Share on other sites
Guest gfinnebraska
Guest gfinnebraska
Posted

I could eat anything until giving birth to my sons. That triggered the celiac for me. It took me YEARS to discover the celiac. I always tease my boys that if it weren't for them I would be enjoying donuts with my coffee!!! :D:D:D

Link to comment
Share on other sites
MySuicidalTurtle Enthusiast
MySuicidalTurtle
Posted

You still had the disease, though. It's just that you didn't have reactions. You are better off knowing than not having symptoms and eating it.

Link to comment
Share on other sites
tarnalberry Community Regular
tarnalberry
Posted

From the research I've read, no - she might not actually have had the disease. Not all genetic conditions are active from birth because not all genes are always expressed. You CAN go through some (or all) of your life with the genes that predispose you to getting the damage that is celiac disease, but not have them expressed, so that your immune system does not respond to gluten - hence you don't have the disease. You just have the genetic propensity to develop it.

Link to comment
Share on other sites
Guest gfinnebraska
Guest gfinnebraska
Posted

My understanding is the same as yours, Tiffany. Hence why I tease my sons! So far I am the only one in my family that has it. I hope it remains that way!!!

Link to comment
Share on other sites
MySuicidalTurtle Enthusiast
MySuicidalTurtle
Posted

I know we have talked about this before and I still go with that you always have it.

Link to comment
Share on other sites
celiac3270 Collaborator
celiac3270
Posted
You still had the disease, though.  It's just that you didn't have reactions.  You are better off knowing than not having symptoms and eating it.

That doesn't mean she had the disease before. She had a predisposition to it, but it might never have developed into full-blown celiac. Certain things can trigger celiac disease, such as surgery or major stress....but it doesn't just bring out symptoms of a disease that was already there.

I know we have talked about this before and I still go with that you always have it.

Sorry, but I'm with Tiffany and Kimberly on this one. You do have to have certain genes to develop celiac: the HLA DQ2 or HLA DQ8..... Without these genes you cannot develop celiac disease under any circumstances, which is why in relatives of celiacs who do not have the gene, follow up testing is unnecessary. Anyway, my point is that the gene is always there, but the celiac disease is not.

Oh, Dr. Green also thinks so :P

Link to comment
Share on other sites

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. plumbago
      - plumbago replied to Suzi374's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

      I'm also a nurse, but one who has worked in chronic care, and to some extent, it is more satisfying to see patients through to a diagnosis (as opposed to working in the ED), but an accurate diagnosis does not occur not as often as it should! Your posting presents a lot of information. But a couple of things I can respond to. One, celiac disease is diagnosed...
    2. trents
      - trents replied to Suzi374's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

      Was a biopsy done when you had your gastroscopy? Concerning your anemia, are you B12 deficient? It's nearly impossible to get sufficient B12 if you are a vegetarian unless you take supplements.
    3. Suzi374
      - Suzi374 replied to Suzi374's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

      And I’m anaemic, however I’m also female and vegetarian. I had an iron trans a couple of years ago however it’s starting to dwindle and taking supplements doesn’t seem to work. I can’t seem to absorb it.
    4. Suzi374
      - Suzi374 posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

      Hi, I attended a neurologist appt last Tuesday, which I nearly cancelled, due to ongoing numbness and tingling in toes to mid foot. One of the first things he asked was ‘are you celiac’. I’m not. He thought all reflexes were ok but at the last minute decided on nerve conduction tests which were low normal. He was a little confused as he felt they should be be...
    5. Peace lily
      - Peace lily posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      0

      Would like to gain weight

      Im still not gaining weight I’m on a gluten free diet . And still having issues with constapation started priobiocs figured it would help been over two weeks . I guess it’s going to be a long road for me .
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      121,226
    • Most Online (within 30 mins)
      7,748
    NYKaren
    Newest Member
    NYKaren
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • plumbago
      Lots of tests

      By plumbago · Posted

      I'm also a nurse, but one who has worked in chronic care, and to some extent, it is more satisfying to see patients through to a diagnosis (as opposed to working in the ED), but an accurate diagnosis does not occur not as often as it should! Your posting presents a lot of information. But a couple of things I can respond to. One, celiac disease is diagnosed by endoscopy and biopsy of the duodenum. So, pathology will need to weigh in. It's not diagnosed on gastroscopy. (At least, not as far as I know). Two, did you get blood tests for celiac disease? You will need to be eating gluten in order for those to be accurate. Three, where was the CT angiogram (of what)? I could go on and on, but thought I'd start there.
    • trents
      Lots of tests

      By trents · Posted

      Was a biopsy done when you had your gastroscopy? Concerning your anemia, are you B12 deficient? It's nearly impossible to get sufficient B12 if you are a vegetarian unless you take supplements.
    • Suzi374
      Lots of tests

      By Suzi374 · Posted

      And I’m anaemic, however I’m also female and vegetarian. I had an iron trans a couple of years ago however it’s starting to dwindle and taking supplements doesn’t seem to work. I can’t seem to absorb it. 
    • Suzi374
      Lots of tests

      By Suzi374 · Posted

      Hi, I attended a neurologist appt last Tuesday, which I nearly cancelled, due to ongoing numbness and tingling in toes to mid foot. One of the first things he asked was ‘are you celiac’. I’m not. He thought all reflexes were ok but at the last minute decided on nerve conduction tests which were low normal. He was a little confused as he felt they should be better and tried a new set of probs, all the time, giving me multiple shocks which were not enjoyable lol. Anyway, he’s now ordered tests for myeloma, and all the vitaminy things that so many of you mention on here, also tests looking for autoimmune responses. I already have Hashimotos. Interestingly, to me, but maybe someone out there can relate or knows more than i do, although I was a nurse, but ED not ‘weird symptoms’  nurse. Anyway back to the interesting thing, I took duramine in 2013 to lose weight which caused a massive panic attack when I stopped taking it and half my hair fell out. I only took it for a week but it was horrible and I regret it. It triggered ongoing panic attacks which are horrendous. So I feel like I’m a bit crazy. Then in 2020 I had this sudden onset of horrible pain when trying to eat a cinnamon roll. It continued and I lost around 20 kgs. I had two gastroscopes and a colonoscopy and they were all normal. I scored a barium swallow and CT angiogram. All normal. The pain subsided a little but I was left with reflux and an awful feeling that I couldn’t get air when I ate some foods. This was not anxiety.  The anxiety was separate and I still maintain this. This was something to do with eating. It was like the air was thick but I wasn’t short of breath. I just had the sensation I was, then it triggered anxiety. Anyway, I had other weird things- couldn’t bend knees to shave legs in shower lol. Knees felt stiff and swollen but they weren’t. Knee WOUld swell up randomly but mri showed minimal issues. A bit of a meniscus degeneration but insignificant. Then the buzzing sensations in my head, the feeling like someone was stabbing me with something sharp. So now, I pre empted his tests, although I don’t think I’m celiac because it should have come up on gastroscopy, I’ve gone off gluten. Since Tuesday last week so 9 days. Since then I don’t appear to be as constipated, I realised I got through today without a nap and I’m not tired, maybe it’s just today and not related but I get very tired normally and sleep straight after work often, I can bend my knees and shave my legs lol, the buzzing vibrating has gone from my head, I had to call and ambulance as my heart decided we were off on a run, but we weren’t running and I’ve been a bit twitchy at bed time when trying to sleep, reflux is improving, I did get the weird suffocating feeling a bit when eating today but not as bad normall. Tingling and numbness still present and I felt like it moved up my legs a bit today but I’m a bit jittery. So I don’t know if it’s celiac disease or a gluten intolerance but I think, and it may be wishful thinking because my symptoms do make life a bit challenging, but maybe I’m feeling better. I don’t feel as cloudy. My thinking feels crisper. Like there’s no buzzing and I’m not fighting to break through the cloudiness now. I hope so much that this may help me feel a bit better moving forward. It would be a miracle as I really have struggled to work and parent and keep the house clean and I’m always anxious and exhausted.  If you get this far, please tell me if you you can relate to any of the above. Oh and tonsils out 5 years ago but before that antibiotics multiple times a year, sometimes intramuscular because they were so bad.  Op was meant to take 30 mins, it took 1.5 hours due to size of them. 
    • Peace lily
      Would like to gain weight

      By Peace lily · Posted

      Im still not gaining weight I’m on a gluten free diet . And still having issues with constapation started priobiocs figured it would help been over two weeks . I guess it’s going to be a long road for me .
×
×
  • Create New...