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Celiac.com Celiac Disease & Gluten-Free Diet Forum: What's The Skinny ? - Celiac.com Celiac Disease & Gluten-Free Diet Forum

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#1 User is offline   Tabasco 

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Posted 14 August 2009 - 07:48 PM

What's the skinny on how & why gluten affects our mood or behavior?
I don't understand the connection yet. Can someone please explain it to me?

Thanks!!!
:D
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#2 User is offline   elle's mom 

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Posted 14 August 2009 - 07:53 PM

View PostTabasco, on Aug 14 2009, 08:48 PM, said:

What's the skinny on how & why gluten affects our mood or behavior?
I don't understand the connection yet. Can someone please explain it to me?

Thanks!!!
:D


As far as I know it's partially undigested gluten-molecule/particles circulating in the bloodstream and accumulating in the brain............can anyone else expand on this into more detail?? I'm no expert. I recently read (skimmed) this is "Recongnizing Celiac Disease".
~Jackie (Mom of a gluten & dairy-free home)
Myself: Neg blood tests despite myriad of life-long symptoms. Enterolab testing positive for gluten sensitivity: DQ5DQ5. Currently gluten, dairy, grain, & sugar free and on rotation diet.
5yo dd diagnosed celiac by blood test/biopsy Oct/Nov 2007: DQ2DQ5
7yo dd: neg blood tests, DQ5DQ6
3yo ds: neg blood tests, IgA deficient, DQ5DQ6
21mo dd: DQ2DQ5
DH: Neg blood tests, by deductive reasoning: DQ2DQ6.
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#3 User is offline   ravenwoodglass 

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Posted 15 August 2009 - 11:57 AM

Once your body starts producing antibodies they can basically attack any organ in your body. I think it is the antibody reaction that can cause the effects on our mood and behavior. I have severe neuro effects from gluten including ataxia and overwhelming depression that now that I am gluten free is short lived. Unfortunately it seems doctors have a hard time understanding this and even when brought research on the neuro effects of gluten they still seem to just stick it in my file without even looking at it. I am seeing a therapist and psychiatrist to try and resolve my panic attacks and agoraphobia and I am still fighting them both over this issue. My last visit my therapist asked how my depression was and when I stressed once again that I am only depressed when I get glutened she gave me 'the look' and said ooookay....
Courage does not always roar, sometimes courage is the quiet voice at the end of the day saying
"I will try again tommorrow" (Mary Anne Radmacher)


celiac 49 years - Misdiagnosed for 45
Blood tested and repeatedly negative
Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002
Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis
All bold resoved or went into remission with proper diagnosis of Celiac November 2002
Some residual nerve damage remains as of 2006- this has continued to resolve after eliminating soy in 2007

Mother died of celiac related cancer at 56
Twin brother died as a result of autoimmune liver destruction at age 15

Children 2 with Ulcers, GERD, Depression, , 1 with DH, 1 with severe growth stunting (male adult 5 feet)both finally diagnosed Celiac through blood testing and 1 with endo 6 months after Mom


Positive to Soy and Casien also Aug 2007

Gluten Sensitivity Gene Test Aug 2007
HLA-DQB1 Molecular analysis, Allele 1 0303

HLA-DQB1 Molecular analysis, Allele 2 0303

Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)
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#4 User is offline   bluejeangirl 

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Posted 16 August 2009 - 09:47 AM

Some researchers believe that in gluten intolerant people gluten may be broken down into small peptides that cross the blood brain barrier and interact with receptors intended for endorphins and other endogenous opiates produced by the body. Also most of the problem is just Malabsorption and with that you'll have high levels of adrenocorticotropic hormone (ACTH) and acetylcholine (ACh) often referred to as stress hormones. These high levels of ACTH and ACh interfere with learning and create anxiety, the desire to escape, a fear of new or unfamiliar things, and poor conditioning response.

Gail
Gluten Free since Jan. 06
Gluten intolerant. DQ 0301 DQ 0602
Lactose intolerant.
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#5 User is offline   Tabasco 

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Posted 17 August 2009 - 02:33 PM

Thanks y'all!!!!
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