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Celiac.com Celiac Disease & Gluten-Free Diet Forum: Scientists Pinpoint Critical Molecule To Celiac Disease - Celiac.com Celiac Disease & Gluten-Free Diet Forum

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Scientists Pinpoint Critical Molecule To Celiac Disease Rate Topic: -----

#1 User is offline   ENF 

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Posted 07 September 2009 - 03:16 PM

More groundbreaking Celiac research news from Dr. Alessio Fasano and his colleagues.

Scientists Pinpoint Critical Molecule To Celiac Disease, Possibly Other Autoimmune Disorders

ScienceDaily (Sep. 7, 2009) — It was nine years ago that University of Maryland School of Medicine researchers discovered that a mysterious human protein called zonulin played a critical role in celiac disease and other autoimmune disorders, such as multiple sclerosis and diabetes. Now, scientists have solved the mystery of zonulin's identity, putting a face to the name, in a sense. Scientists led by Alessio Fasano, M.D., have identified zonulin as a molecule in the human body called haptoglobin 2 precursor.
Complete article here: http://www.sciencedaily.com/releases/2009/...90907162322.htm

Celiac diagnosis from positive blood work & endoscope (2005)

Serologic equivalent: HLA-DQ 2,3 Subtype 2,8 (double Celiac genes)
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#2 User is offline   nasalady 

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Posted 07 September 2009 - 09:33 PM

View PostENF, on Sep 7 2009, 04:16 PM, said:

More groundbreaking Celiac research news from Dr. Alessio Fasano and his colleagues.

Scientists Pinpoint Critical Molecule To Celiac Disease, Possibly Other Autoimmune Disorders

ScienceDaily (Sep. 7, 2009) — It was nine years ago that University of Maryland School of Medicine researchers discovered that a mysterious human protein called zonulin played a critical role in celiac disease and other autoimmune disorders, such as multiple sclerosis and diabetes. Now, scientists have solved the mystery of zonulin's identity, putting a face to the name, in a sense. Scientists led by Alessio Fasano, M.D., have identified zonulin as a molecule in the human body called haptoglobin 2 precursor.
Complete article here: http://www.sciencedaily.com/releases/2009/...90907162322.htm


Very interesting....thanks for your post!

JoAnn
Multiple autoimmune diseases, including celiac, Hashimoto's, psoriasis, autoimmune hepatitis, RA, SLE. Also have fibromyalgia.

Tested Fall 2008: bloodwork, biopsy negative; HLA DQ8. Doctor believes results negative due to prednisone and Imuran taken for autoimmune hepatitis.

Dx with celiac disease because of dietary response, genetics, and family history of celiac disease.


Dx with Lyme Disease Jan 2010; Lyme likely triggered some of the AI diseases.

Gluten free since 25 Nov 2008
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#3 User is offline   captaincrab55 

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Posted 08 September 2009 - 12:47 AM

Great Find!.... One can also view the article on The University of Maryland School of Medicine's site

http://somvweb.som.umaryland.edu/absoluten.../?a=893&z=5
I'm a New Man Without GLUTEN!
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#4 User is offline   RiceGuy 

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Posted 08 September 2009 - 06:30 AM

This is very interesting, and very important! Thanks captaincrab55 for the link. Everyone should check it out, as there is a link at the bottom to a video interview with Dr. Fasano. He goes into much more detail than does the article itself. Amazing!
A spherical meteorite 10 km in diameter traveling at 20 km/s has the kinetic energy equal to the calories in 550,000,000,000,000,000 Twinkies.
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#5 User is offline   captaincrab55 

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Posted 08 September 2009 - 02:33 PM

WOW! Just saw a short segment on WJZ TV 13 about Celiac. It briefly covered the content of the link above. It included a short interview with Dr. Alessio Fasano.. There was some very positive talk about the Drug testing currently going on for that miracle medication..
I'm a New Man Without GLUTEN!
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#6 User is offline   happygirl 

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Posted 08 September 2009 - 03:02 PM

Thank you for sharing...I am thankful for Dr. Fasano's research.
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