Jump to content

Follow Us:  Twitter Facebook RSS Feed            




   arrowShare this page:
   

   Get email alerts  Subscribe to FREE Celiac.com email alerts

 
Ads by Google:
Celiac.com Sponsor:                                    


Photo
- - - - -

Enterolab Results Are In


  • Please log in to reply

7 replies to this topic

#1 Evie4

 
Evie4

    Community Member

  • Advanced Members
  • PipPipPip
  • 53 posts
 

Posted 16 September 2009 - 10:41 AM

I haven't posted much here at Celiac, but I have learned so much from all of you--which brought me to getting myself tested through Enterolab and Kimball. I feel so lucky to have found this site that has led me to some answers--I appreicate all of you who take the time to post and share.

These results give me hope now that maybe my health will contionue improve as I lead a gluten free life and I can regain some of my spunk that I miss so much. My IBS has improved with gluten reduction over the past year and I'm hoping 100% elimination will bring even greater results. After 16 years, it would be like a miracle!

Here are my results, for anyone interested in seeing them or wanting to comment on them. At this point I'm convinced gluten causes a immune response and I should never eat gluten again! Oh...I added the parenthetical values along side of my reported values.

For those interested in testing. I was 95% gluten free for a year and 100% gluten free for a month before the test.
Evie

Gluten Sensitivity Stool and Gene Panel
Fecal Anti-gliadin IgA: 23 Units (<10)
Fecal Anti-tissue Transglutaminase IgA: 16 Units (<10)
Quantitative Microscopic Fecal Fat Score: 465 Units (<300)
Fecal Anti-casein (cow's milk) IgA: 15 Units (<10)

HLA-DQB1 Molecular analysis, Allele 1: 0301 (gluten sensitivity gene - from one parent)
HLA-DQB1 Molecular analysis, Allele 2: 0602 (gluten sensitivity gene - from other parent)
Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

HLA-DQA1 Molecular analysis, Allele: 0501/0505 (from Kimball lab testing)

Egg, Yeast, and Soy Food Sensitivity Stool Panel
Fecal Anti-ovalbumin (chicken egg) IgA: 6 Units (<10)
Fecal Anti-saccharomyces cerevisiae (dietary yeast) IgA: 10 Units (<10)
Fecal Anti-soy IgA: 7 Units (<10)
  • 0

Celiac.com Sponsor:

#2 ravenwoodglass

 
ravenwoodglass

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 13,743 posts
 

Posted 16 September 2009 - 02:33 PM

I am glad you got results that show you are on the right track. Now you can stop wondering and do the diet strictly along with eliminating casein and hopefully soon the fecal fat score will go down to normal levels. With your yeast score right at the cut off you might consider trying to reduce or cut that also. Happy healing.
  • 0
Courage does not always roar, sometimes courage is the quiet voice at the end of the day saying
"I will try again tommorrow" (Mary Anne Radmacher)


celiac 49 years - Misdiagnosed for 45
Blood tested and repeatedly negative
Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002
Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis
All bold resoved or went into remission with proper diagnosis of Celiac November 2002
Some residual nerve damage remains as of 2006- this has continued to resolve after eliminating soy in 2007

Mother died of celiac related cancer at 56
Twin brother died as a result of autoimmune liver destruction at age 15

Children 2 with Ulcers, GERD, Depression, , 1 with DH, 1 with severe growth stunting (male adult 5 feet)both finally diagnosed Celiac through blood testing and 1 with endo 6 months after Mom


Positive to Soy and Casien also Aug 2007

Gluten Sensitivity Gene Test Aug 2007
HLA-DQB1 Molecular analysis, Allele 1 0303

HLA-DQB1 Molecular analysis, Allele 2 0303

Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)

#3 Evie4

 
Evie4

    Community Member

  • Advanced Members
  • PipPipPip
  • 53 posts
 

Posted 17 September 2009 - 08:57 AM

I am glad you got results that show you are on the right track. Now you can stop wondering and do the diet strictly along with eliminating casein and hopefully soon the fecal fat score will go down to normal levels. With your yeast score right at the cut off you might consider trying to reduce or cut that also. Happy healing.


Thanks for you comment. Interesting on the yeast, I rarely eat anything with yeast--it's really only been the gluten free bread the past year and not a whole lot of it. I'll avoid that for now. I'm so glad I did this testing and didn't procrastinate about it. Again, I'm so grateful to the board and you posters!
  • 0

#4 nora_n

 
nora_n

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 1,489 posts
 

Posted 19 September 2009 - 09:58 AM

Are you aware of the fact that the Kimball test proves you have half a celiac gene?
You officially have half a DQ2!
(it is in the alpha chain of your DQ7. But not all DQ7 do have this) (to read more, go to the HLA DQ page on wikipedia, and the HLA DR page too)

You might want to notify Enterolab, I wish they informed patients that they most likely do have half a celiac gene when they have DQ7, and not just call it gluten sensitive. They miss a lot of cleiacs that way. There have been several postings about that here before.

There have even been DQ7/DQ2,2 positive people here where Enterolab has not bothered to telle them that. The 05* alpha chain and the 2,2 beta chain together are the official 2,5 celiac gene in trans.

nora
  • 0
gluten-free since may 06 after neg. biopsy symptoms went away and DH symptoms which I had since 03 got gradually better.
daughter officially diagnosed celiac and casein intolerant.
non-DQ2 or DQ8. Maybe DQ1? Updated: Yes, double DQ5
Hypothyroid since 2000, thyroxine first started to work well 06 on a low-carb and gluten-free diet
Lost 20 kg after going gluten-free and weighing 53 kg now. neg. biopsy for DH. Found out afterwards from this forum that it should have been taken during an outbreak but it was taken two weeks after. vitaminD was 57 nmol/l in may08)

#5 Evie4

 
Evie4

    Community Member

  • Advanced Members
  • PipPipPip
  • 53 posts
 

Posted 19 September 2009 - 07:12 PM

Are you aware of the fact that the Kimball test proves you have half a celiac gene?
You officially have half a DQ2!
(it is in the alpha chain of your DQ7. But not all DQ7 do have this) (to read more, go to the HLA DQ page on wikipedia, and the HLA DR page too)

You might want to notify Enterolab, I wish they informed patients that they most likely do have half a celiac gene when they have DQ7, and not just call it gluten sensitive. They miss a lot of cleiacs that way. There have been several postings about that here before.

There have even been DQ7/DQ2,2 positive people here where Enterolab has not bothered to telle them that. The 05* alpha chain and the 2,2 beta chain together are the official 2,5 celiac gene in trans.

nora


Thanks for pointing that out Nora. Yes, I did test with Kimball for the alpha (just incase) there was something there, and sure enough! I indicated the *05 to Enterolab in the voluntary survery.

I understand that the alleles DQA1 *0501/DQB1 *0301 (that I possess) make DQ7 (DQ7.5) So, this means the 0501 reported by Kimball as the 1/2 DQ2 completes this gene or(?) Kimball said *05 raised the risk about 3% (I've read 5% of celiacs in one study were solely 1/2 DQ2 *05). What does DQ7 mean in terms of risk--do you know? I couldn't find any numbers. I'm also curious now with these 3 alleles how this is expressed in DQ(?) DQ2/DQ7 (?) 0602 excluded?

Evie
  • 0

#6 nora_n

 
nora_n

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 1,489 posts
 

Posted 20 September 2009 - 02:54 AM

Hi, about 5% of celiacs have half a gene, maybe like you said 5% have half the DQ2, 05*.

In your case this does not make up anything else, since you do not have the DQ2,2.

Maybe you can call yourself DQ7,5, DQ6 and half a DQ2? What would you prefer?

I am still a bit upset that enterolab does not point that out, that DQ7 may be half DQ2, and thus have a celiac gene.

There are other genes that predispose towards celiac, like the Myo9b and another thing I forgot, DQ is just 40%. The greatest risk is still having a celiac relative.

nora
  • 0
gluten-free since may 06 after neg. biopsy symptoms went away and DH symptoms which I had since 03 got gradually better.
daughter officially diagnosed celiac and casein intolerant.
non-DQ2 or DQ8. Maybe DQ1? Updated: Yes, double DQ5
Hypothyroid since 2000, thyroxine first started to work well 06 on a low-carb and gluten-free diet
Lost 20 kg after going gluten-free and weighing 53 kg now. neg. biopsy for DH. Found out afterwards from this forum that it should have been taken during an outbreak but it was taken two weeks after. vitaminD was 57 nmol/l in may08)

#7 nora_n

 
nora_n

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 1,489 posts
 

Posted 20 September 2009 - 03:24 AM

By the way, I have been reading here for some years, and always wondered where all the half genes were.
Glad to have found you.
Just proves they did not est for them before, and that enterolab did not tell people that they might have half the gene (with DQ7) since most DQ7 are 7,5
  • 0
gluten-free since may 06 after neg. biopsy symptoms went away and DH symptoms which I had since 03 got gradually better.
daughter officially diagnosed celiac and casein intolerant.
non-DQ2 or DQ8. Maybe DQ1? Updated: Yes, double DQ5
Hypothyroid since 2000, thyroxine first started to work well 06 on a low-carb and gluten-free diet
Lost 20 kg after going gluten-free and weighing 53 kg now. neg. biopsy for DH. Found out afterwards from this forum that it should have been taken during an outbreak but it was taken two weeks after. vitaminD was 57 nmol/l in may08)

#8 Evie4

 
Evie4

    Community Member

  • Advanced Members
  • PipPipPip
  • 53 posts
 

Posted 20 September 2009 - 08:18 AM

There are other genes that predispose towards celiac, like the Myo9b and another thing I forgot, DQ is just 40%. The greatest risk is still having a celiac relative.

nora


It would be nice if my immediate family would be tested, there certainly are indicators...but for the most part there is silence to my news, so that part I'm not likely to find out unfortunately. Not unless any of my siblings (or their children) symptoms get progressively worse like mine did and they get desperate for an answer.

It does seem, with the reporting of "gluten sensitivity genes" that Enterolab would make that acknowledgement if/when they know the association with *05 and DQ7 and relay the risk associated. Another case of multiple info sources payoff! Thanks for the info. Thank heavens for the internet!
  • 0




0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users

Celiac.com Sponsors: