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Could My Bipolar Be Caused By Celiac?


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#1 fitbunni

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Posted 05 April 2010 - 01:36 PM

I have bipolar disorder and was wondering if maybe it could be because of celiac? anyone have any experience with this?
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#2 ravenwoodglass

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Posted 06 April 2010 - 04:15 AM

I had a seizure disorder whose symptoms closely resembled Bipolar. Long lasting 'highs' and horrible crushing lows. No issues with either since I have been gluten free but if glutened the depression hits hard, fast and is over within 24 hours. I was on a very strong antiseizure med for a long time but don't need it now. Celiac doesn't cause everything, I still have an anxiety disorder and PTSD but the bipolar aspect of my brain impact has resolved. Don't know if it will be the same for you. One thing that has to be mentioned is that if you are on meds and you think you may not need them any longer DO NOT stop them on your own suddenly. Talk to your doctor and get his help weaning off of them.
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Courage does not always roar, sometimes courage is the quiet voice at the end of the day saying
"I will try again tommorrow" (Mary Anne Radmacher)


celiac 49 years - Misdiagnosed for 45
Blood tested and repeatedly negative
Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002
Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis
All bold resoved or went into remission with proper diagnosis of Celiac November 2002
Some residual nerve damage remains as of 2006- this has continued to resolve after eliminating soy in 2007

Mother died of celiac related cancer at 56
Twin brother died as a result of autoimmune liver destruction at age 15

Children 2 with Ulcers, GERD, Depression, , 1 with DH, 1 with severe growth stunting (male adult 5 feet)both finally diagnosed Celiac through blood testing and 1 with endo 6 months after Mom


Positive to Soy and Casien also Aug 2007

Gluten Sensitivity Gene Test Aug 2007
HLA-DQB1 Molecular analysis, Allele 1 0303

HLA-DQB1 Molecular analysis, Allele 2 0303

Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)

#3 StacyA

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Posted 06 April 2010 - 05:04 PM

Most research points to bipolar being an inherited condition - not 'caused' by anything else including celiac's. (It's not terribly common, yet if one identical twin has bipolar there's a 70% chance the other twin has it. Even though a person is born with bipolar, it usually manifests in late teens or early adulthood.) However celiac disease can cause mood swings and some people may confuse the two on the surface.

Also, a person could have legitimate bipolar that could be worsened if they have celiac's and eat gluten.

Some ways to differentiate between the two: Do the mood swings totally go away on a gluten-free diet - then it may be just celiac. Do the mood swings even out with mood stabilizing medication, regardless of diet - then it may be bipolar. Are there other family members with bipolar - then it may be bipolar.

If you're unsure - get second or even third opinions from people who are familiar with both celiac's and bipolar. Bipolar disorder is often overdiagnosed and often underdiagnosed. If someone truly has bipolar then medication is necessary and very helpful - true bipolar is biochemically caused - not something you can control with willpower or a gluten-free diet.
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#4 ravenwoodglass

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Posted 07 April 2010 - 03:11 AM

Some ways to differentiate between the two: Do the mood swings totally go away on a gluten-free diet - then it may be just celiac. Do the mood swings even out with mood stabilizing medication, regardless of diet - then it may be bipolar.


For me the symptoms did thankfully totally resolve on the diet. And they resolved pretty quickly. I should note that any antidepressant meds or meds for bipolar made me much worse, because I wasn't really bipolar I was celiac.

I am very thankful that the diet took care of those issues. It does make me wonder how often some of us are diagnosed with a mental illness and medicated when a change in diet is what is really needed.

If the diet doesn't have any effect on your symptoms of bipolar then it is likely your bipolar. If you are don't feel defeated but do seek out help whether it is through talk therapy, medication or a combo of both.
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Courage does not always roar, sometimes courage is the quiet voice at the end of the day saying
"I will try again tommorrow" (Mary Anne Radmacher)


celiac 49 years - Misdiagnosed for 45
Blood tested and repeatedly negative
Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002
Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis
All bold resoved or went into remission with proper diagnosis of Celiac November 2002
Some residual nerve damage remains as of 2006- this has continued to resolve after eliminating soy in 2007

Mother died of celiac related cancer at 56
Twin brother died as a result of autoimmune liver destruction at age 15

Children 2 with Ulcers, GERD, Depression, , 1 with DH, 1 with severe growth stunting (male adult 5 feet)both finally diagnosed Celiac through blood testing and 1 with endo 6 months after Mom


Positive to Soy and Casien also Aug 2007

Gluten Sensitivity Gene Test Aug 2007
HLA-DQB1 Molecular analysis, Allele 1 0303

HLA-DQB1 Molecular analysis, Allele 2 0303

Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)

#5 ElitaSue

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Posted 07 April 2010 - 11:43 AM

I have bipolar disorder and was wondering if maybe it could be because of celiac? anyone have any experience with this?


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#6 ElitaSue

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Posted 07 April 2010 - 11:55 AM

I have bipolar disorder and was wondering if maybe it could be because of celiac? anyone have any experience with this?


Hi Fitbunni,

I was diagnosed Bipolar when I was 21 and went through years and years of a litany of medications, counseling and so on with no real relief. Fast forward to age 42 - I began to notice a real correlation between my wicked mood swings and those yummy chocolate donuts with the great icing I loved to eat with everybody at work. I bought a glucose meter an found out about 20 minutes after eating "yummy chocolate donut", nasty mood and panic attack would start - the glucose meter would read 40. I know now that is when I would experience a complex partial seizure. By that point in my "bipolar" illness my doc had thankfully put me on a anti-convulscent drug called Lomotrigine - which helped greatly. After discovering the weird deal with my blood sugar, my GP sent me to see a Endocrinologist who made my Celiac disease diagnosis.

No longer experience the mood swings, but still take Lomotrigine. My Endocrinologist put me on a completely grain-free, sugar free diet. I am so very grateful that I found out. Some of the meds for bipolar are actually worse than the disease. If there is any chance that a diet switch will help, I encourage you to try it out.

Guess many of we Celiacs have had our turn with psychological and neurological problems.

Best of luck!
ElitaSue
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#7 masterjen

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Posted 08 April 2010 - 06:49 AM

I think no one can answer for certain if your bipolar might be caused by (or related to) being gluten-intolerant or having celiac unless you actually try the diet (UNDER STRICT SUPERVISION BY YOUR PSYCHIATRIST AND FAMILY DOCTOR). However, recent research I've seen has found a higher percentage of celiac disease and gluten intolerance in several groups of people with mental and physical ailment compared to the general population: autistics, schizophrenics, people with rheumatoid arthritis, and those suffering from depression. "Google" some of this yourself so you get a good sense of whether you want to believe the research or if you feel it is all just coincidence - it is very interesting, but check into carefully for yourself and come to your own conclusions. Again, if you decide you want to modify your diet or your current treatment regime, make sure it is done with your doctors' supervision.
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Life throws us curve-balls sometimes, but if we didn't have challenges we would become too complacent and forget to respect the value of life itself.

#8 ravenwoodglass

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Posted 08 April 2010 - 03:53 PM

Again, if you decide you want to modify your diet or your current treatment regime, make sure it is done with your doctors' supervision.


I would agree that the doctor needs to be kept in the loop as far as the diet changes go but you really don't need a doctors supervision to try it and see if it helps. If it does help you may need to modify meds that you are on and that should be done in close contact with your doctor but IMHO you don't need a doctors permission to try the diet.
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Courage does not always roar, sometimes courage is the quiet voice at the end of the day saying
"I will try again tommorrow" (Mary Anne Radmacher)


celiac 49 years - Misdiagnosed for 45
Blood tested and repeatedly negative
Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002
Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis
All bold resoved or went into remission with proper diagnosis of Celiac November 2002
Some residual nerve damage remains as of 2006- this has continued to resolve after eliminating soy in 2007

Mother died of celiac related cancer at 56
Twin brother died as a result of autoimmune liver destruction at age 15

Children 2 with Ulcers, GERD, Depression, , 1 with DH, 1 with severe growth stunting (male adult 5 feet)both finally diagnosed Celiac through blood testing and 1 with endo 6 months after Mom


Positive to Soy and Casien also Aug 2007

Gluten Sensitivity Gene Test Aug 2007
HLA-DQB1 Molecular analysis, Allele 1 0303

HLA-DQB1 Molecular analysis, Allele 2 0303

Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)

#9 starrytrekchic

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Posted 11 April 2010 - 09:15 PM

I have bipolar disorder and was wondering if maybe it could be because of celiac? anyone have any experience with this?


They're completely separate illnesses, but because celiac can affect moods (and people with it can be lacking in certain vitamins/minerals necessary for proper brain functioning), celiac might exacerbate bipolar symptoms.

A gluten free diet might clear up some intermediate mood swings, some mild depression, and some other symptoms you may be associating with bipolar disorder, but it's not going to stop a full on manic or depressive episode.

Also, if I remember right, they're both illnesses that *can* be triggered by an environmental stimulus (emotional trauma, severe physical illness) in a genetically susceptible person...so they may have been triggered by the same thing. It doesn't mean they share any genes in common or one causes the other.
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#10 Guest_doradomiel_*

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Posted 14 April 2010 - 04:36 PM

YES
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#11 Guest_doradomiel_*

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Posted 14 April 2010 - 04:56 PM

I guess I should elaborate, but I didn't want to sound long winded.

Yes, it could cause you to "seem" Bipolar. If it is Celiac, you would have to stop the gluten and address the deficiency that has caused your brain chemistry to become unbalanced. The main one is usually a B-vitamin deficiency... Calcium and magnesium could be lacking as well.

Talk to a GOOD doctor who wants to get to the bottom of this and not somebody who just wants to keep you on medication for the sake of being able to write a prescription.
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#12 Skylark

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Posted 26 April 2010 - 10:21 AM

I had depression and anxiety caused by what I know now was gluten. I was treated with Prozac, which gave me manic episodes and ended up diagnosed as bipolar and on lithium and depakote.

Six months after going gluten-free the fatigue and depressive episodes stopped. With the help of my psychiatrist I tried going off the meds that were barely working anyway and onto EMPowerPlus and fish oil. I started feeling better after my body adjusted for a couple months and after six months of the regimen I was in the best mental health I had enjoyed in over a decade. My doctor declared me in remission over three years ago.

So in my case celiac -> depression -> SSRIs -> bipolar.

You may have totally different chemistry and physiology and untreated bipolar can wreck your life, so please take my story with a grain of salt.
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#13 AlysounRI

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Posted 26 April 2010 - 12:05 PM

I am very thankful that the diet took care of those issues. It does make me wonder how often some of us are diagnosed with a mental illness and medicated when a change in diet is what is really needed.


I have often wondered the same thing.
But in regards to historical mental illness or how it was labelled.

I once had a friend that suffered from very extreme type 1 diabetes and had very extreme highs and lows.
Her highs were so high that people called the psych ward at times because they thought she was very unstable. Once you knew her or were around her, you could tell when one of these was approaching and could suggest to her that she needed to check her sugar levels and correct them.

But it does make me wonder how many people in psych wards, even in the very near past, were put there because of extreme hyperglycemia or reactions to food allergies.

Food is a form of medication, it may be the best form of medication, once you know what your own body requires, that is!!

~Allison
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Long history of IBS, and stomach/intestinal problems. Low on iron for all of my life.
Low on energy, with aches and pains in my joints and in my whole body for as long as I can remember.
Mostly lactose intolerant for all of my life (except for yoghurt)
Diagnosed in 2003 by naturapath as wheat intolerant. Tried it then fell of the wagon. In Feb. 2010 tried going gluten-free.
Went back to the poison in March, 2010.
Tested negative for celiac in April, 2010 (based on negative biopsy and normal tTG test). IgA tested 30-40 percent higher than normal.
Not going to fight the diagnosis because I refuse to go back to the poison. Happily gluten-free for health reasons as of April 2010, and not looking back.


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