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Asacol Interfere With Gluten Test?

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Posted 12 June 2010 - 09:19 AM

OK, so here's the deal.

About 8 months ago I found an association between peripheral neuropathy, the bane of my existence, and gluten sensitivity. I cut out gluten for 4 months, then found Enterolabs. Did the test and, even though I'd been gluten-free for 4 months at the time, it came back positive for gluten sensitivity with a double DQ1. The tTG and malabsorbtion were negative. While I was off gluten my D mostly resolved, although the neuropathy didn't improve perceptively.

Fast forward 2 months. D returned big time. Felt horrible again. Threw up my hands in disgust and saw GI doctor. He ran battery of tests including colonoscopy with biopsy for microscopic colitis. Yep - it's positive. So he put me on Asacol. But here's the tricky part. He doesn't believe the positive lab from Enterolab and wants me to do a gluten challenge and take anti-gliadin IGG and IGA blood test. The challenge is ongoing with the Asacol now.

My question: will the Asacol mess up the gluten test? Has anyone had any experience with this? I don't want to be wasting my time on the challenge if it's going to be compromised by the drug.

The good news is the Asacol seems to be getting the D under control again. Yay!
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Judyin Philly

    Moved to SO CA in November 2010

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Posted 12 June 2010 - 11:28 AM


After almost 5 1/2 yrs gluten-free moved to CA and Dr looked at old tests for cleiac panel, said didn't have it
still 99% gluten-free but now microscopic colitis too
Am on Asacol 4 pills 3 times a day
then ulcer in stomach and positive for H-Pylori
the 2 weeks of a 3 drug therapy gave me C-Dif
on vancomycin for 10 days and hoping it gets rid of it

now.......about the drug and gluten challange.
Don't know about an interaction but I'd sure be leary of doing a challange
I f you feel better off gluten..........let your body tell you what to do

Since I've been off c.com for so long, not sure how to get up dates from the link
Good luck in getting better
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Judy in Southern CA

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