Jump to content

Follow Us:  Twitter Facebook RSS Feed            




   arrowShare this page:
   

   Get email alerts  Subscribe to FREE Celiac.com email alerts

 
Celiac.com Sponsor:                                    


Photo
- - - - -

Trying To Understand How To Read These Results


  • Please log in to reply

6 replies to this topic

#1 melikamaui

 
melikamaui

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 190 posts
 

Posted 10 July 2011 - 07:06 PM

Can anyone help me figure out this genetic panel? These are my son's results. I know he has a very high chance of having celiac disease, and his doctor believes that he does in fact have it, she diagnosed him already. I'd just like to know what each of these things stand for.

Thanks for any help.


002.5 (HLA OOA1*05:00B1"(201) and other non-risk alleles.

Category 4, DQ2 heterozygous, Increased Risk 10X, Relative Risk HIGH

Category 8, DQ2 Homozygous, Increased Risk 31X, Relative Risk EXTREMELY HIGH

Category 7, DQ2/other high risk gene, Increased Risk 16X, Relative Risk VERY HIGH

Category 6, DQ2/DQ8, Increased Risk 14X, Relative Risk VERY HIGH

Category 5, DQ8 Homozygous, Increased Risk 10X, Relative Risk HIGH

Category 4, DQ2 heterozygous, Increased Risk 10X, Relative Risk HIGH

Category 3, DQ8 heterozygous, Increased Risk 2X, Relative Risk MODERATE

Category 2, DQ2/other low risk gene, Increased Risk <1X, Relative Risk LOW

Category 1, DQx, DQ8, Increased Risk <o.1, Relative Risk EXTREMELY LOW
  • 0

Celiac.com Sponsor:

#2 melikamaui

 
melikamaui

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 190 posts
 

Posted 11 July 2011 - 10:50 AM

Anyone? Bueller?...
  • 0

#3 Mama Melissa

 
Mama Melissa

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 170 posts
 

Posted 11 July 2011 - 05:08 PM

What category does he fall in? I only see his other risk alleles
  • 0
Melissa
9/10 Diagnosed celiac via bloodwork/endo
9/10 Gluten free

#4 melikamaui

 
melikamaui

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 190 posts
 

Posted 11 July 2011 - 05:20 PM

What category does he fall in? I only see his other risk alleles


DQ2 heterozygous, Increased Risk 10X, Relative Risk HIGH

What do/does the other risk alleles mean? I don't understand that part at all.

Thanks for any help!
Melika
  • 0

#5 Skylark

 
Skylark

    Glutenologist

  • Advanced Members
  • PipPipPipPipPipPip
  • 5,490 posts
 

Posted 11 July 2011 - 09:18 PM

He has one risk allele, DQ2.5, and one non-risk allele which hasn't been specified. That gives him 10x risk for celiac with respect to the general US population.

I'm not sure what else you're asking. What do you mean by "each of these things"? Is this article helpful?

http://en.wikipedia.org/wiki/HLA-DQ
  • 0

#6 melikamaui

 
melikamaui

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 190 posts
 

Posted 12 July 2011 - 07:46 AM

That's very helpful, thanks!
  • 0

#7 nora_n

 
nora_n

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 1,490 posts
 

Posted 12 July 2011 - 01:34 PM

I do not understand the difference between category 1 and 3 in this list
  • 0
gluten-free since may 06 after neg. biopsy symptoms went away and DH symptoms which I had since 03 got gradually better.
daughter officially diagnosed celiac and casein intolerant.
non-DQ2 or DQ8. Maybe DQ1? Updated: Yes, double DQ5
Hypothyroid since 2000, thyroxine first started to work well 06 on a low-carb and gluten-free diet
Lost 20 kg after going gluten-free and weighing 53 kg now. neg. biopsy for DH. Found out afterwards from this forum that it should have been taken during an outbreak but it was taken two weeks after. vitaminD was 57 nmol/l in may08)




0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users

Celiac.com Sponsors: