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What Tests Make A Complete Celiac Blood Panel?
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What lab tests should be ordered for a complete celiac panel? My 18 month old son reacted violently to we suspect wheat when introduced to solids. Genetic tests show 2 copies of DQ8 for my son. I've had tons of weird symptoms for years and am scheduled for a biopsy next week. My husband recently mentioned he's had loose stools for years, and he also is physically short stature and so skinny (I'm jealous!). He's considering getting tested to see if he could have celiac. His mom also mentioned she goes between consipation and loose stools and suffers from heartburn/acid reflux and is scheduled to have surgery for that (she mentioned my son's possible celiac to her GI doctor and when they did a endoscopy it doesn't sound like they looked for signs of celiac). Could heartburn/acid reflux go with celiac? If so it would maybe be nice to get my husband blood tested before his mom's surgery so getting into a family doctor would be quicker than a GI doctor. But our family clinic didn't run a complete celiac panel on my son so I don't know what one would involve and if we could find out what lab work we should ask for that would be wonderful!

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The following is usually considered to be a complete celiac panel:

Anti-Gliadin (AGA) IgA

Anti-Gliadin (AGA) IgG

Anti-Endomysial (EMA) IgA

Anti-Tissue Transglutaminase (tTG) IgA

Deamidated Gliadin Peptide (DGP) IgA and IgG

Total Serum IgA

The last test is a control to make sure that normal amounts of IgA are produced, otherwise the IgG versions of the tests need to be run also.

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Which of these in the celiac panel determines your gluten level?

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There is no one test that tells you a level of gluten you are eating. The deamidated gliadin peptide (DGP) is thought to be the quickest to react to gluten ingestion or removal, but does not indicate that a certain amount of gluten has been consumed. It would be an awesome test to have access to.

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    • A new study confirms a link between intestinal viral infections and celiac disease. View the full article
    • Good luck with all the testing.  You are doing the right thing by telling your son to gluten up!  Buy him one of those gluteny cakes at a bakery...if that doesn't spike his numbers, nothing will. 
    • Thank you for this response! You are right, I'm sure. My sed rate was normal. My c reactive protein was 6, which is high. My platelets were a bit elevated and I was slightly anemic. I am going tomorrow for another endoscopy. I know that these things could be related to other things... but I'm thinking there is a change they are all still related to celiac (I'm hoping). What other autoimmune disease do you have, if you don't mind me asking?
    • HIV doesn't turn off the immune system, it destroys it to the point where most people die from complications that arise from having no immune system.  Some end up with pneumonia or cancer, which takes their life. It is pretty amazing the treatments they have developed for it, to slow it down and give people longer, quality time. I am perfectly content with the gluten free diet as my treatment and honestly, if they developed a pill that they claimed would make it possible for people to eat gluten again, I doubt I would. I could not bring myself to eat a food that I am genetically programmed to not be able to digest and that totally pisses off my immune system.  However, if they succeed with some of the meds they are working on now, one of which I posted about earlier this summer, I would take those.  They are working on things that modulate the immune system down so inflammation can be tamed down further.  Even with a strict gluten-free diet, there will always be more inflammation for us than for those who don't have AI diseases.  I do everything possible to tame it down myself but it isn't in the normal range.....yet. Long term inflammation can kill you so something along those lines would be welcome.  You would still have to eat gluten-free but the disease activity would be calmed down.  This is a drug that targets those with lupus and maybe Sjogren's....which I have.  There are possibilities for other AI diseases from that!
    • Hi Anns and welcome   Do you think that I am on the right course to see if I possibly have Celiac?   Yes, it was smart of you to consider the possibility and its good that you've had the tests. Both the aneamia and bloating are symptoms, although of course they may be unrelated. Best way to find out is to check as you are doing.   Can this develope later in life ( I'm 46)?   Yes, I think its most common discovered later rather than sooner.   I ate a meal last night that was gluten free and did not feel like nearly as bloated after eating, would I notice a change that quickly?  Thanksort for your input.   Yes, I noticed far less of a heavy feeling after eating very soon after diet changes. However you would be better off not trying gluten free just yet. I collected some links and other stuff here, it may be of use: Your best bet is to eat as normal and wait for the test results. If your doctors eliminate celiac there's nothing to stop you excluding gluten at that point to see if it helps. But before then you need to keep eating it to ensure an accurate diagnosis.  All the best  
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