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Exact Opposite Reaction To Meds?


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8 replies to this topic

#1 Duhlina

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Posted 05 October 2011 - 05:42 AM

All my life I seem to have the exact opposite reaction to medications. If I take Nyquil, it's like speed and I'm up all night, same with Benadryl - most people take these and are down for the count. I also seem to have a very high tolerance to pain meds. Basically nothing works. The last time I went to the ER I had an abscessed tooth. They ended up prescribing me Dilaudid (morphine derivative) because nothing else works....well, Darvocet worked but it's been taken off the market. Even the Dilaudid did squat for me! Nothing works! I end up taking one more than I should and then I get sick from it.

Is this something that the celiac causes? Am I the only person that has this symptom?
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#2 lovegrov

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Posted 05 October 2011 - 05:54 AM

I know folks without celiac who have the same thing with Nyqui and Benadryl. And some folks simply have a high resistance to pain meds. Pretty hard to pin it on celiac.

richard
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#3 Jestgar

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Posted 05 October 2011 - 06:12 AM

It can happen to anyone. It's related to body chemistry, not celiac disease.
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#4 love2travel

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Posted 05 October 2011 - 07:56 AM

I have always had this problem as well but do not see a link to my celiac. Benadryl, morphine, Demerol, Oxycontin - you name it, they have kept me wired and wide awake! :angry:

However, my chronic pain management doctor told me that those with fibromyalgia (myself) are extremely sensitive to meds and that side effects can be much worse than those who do not have FMS. And as FMS is an auto-immune disease as well, who knows whether there is a correlation? :huh:
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<p>Confirmed celiac disease February 2011 from biopsies. Strictly gluten free March 18 2011.Diagnosed with fibromyalgia April 13 2011.3 herniated discs, myofascial pain syndrome, IT band syndrome, 2 rotator cuff injuries - from an accident Dec. 07 - resulting in chronic pain ever since. Degenerative disc disease.Osteoarthritis in back and hips.Chronic insomnia mostly due to chronic pain.Aspartame free May 2011.

When our lives are squeezed by pressure and pain, what comes out is what is inside.

#5 Strawberry_Jam

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Posted 05 October 2011 - 10:25 AM

I have the same problem. There are some medicines like that which keep me up but if I take half the dose they put me down.

Caffeine makes me alert if I have one cup of tea, and sleepy if I have a cup of coffee's worth or more.

Pain medications don't work for my headaches, but do help with cramps so idk if I am immune to pain meds or if only my headaches are immune to pain meds.

My mother has the same problem but does not have celiac.
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25 yrs old
diagnosed Celiac through biopsy and blood test (WAY positive) as of 25 Feb 2011


#6 mushroom

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Posted 05 October 2011 - 11:06 AM

Yeah, Nyquil, Benadryl = speed; sleeping pills = insomnia, antidepressants (well, the only one I ever took) made me depressed), pain meds - the onlly thing that works is Demerol (all morphine derivatives make me vomit :huh: , Tylenol will take the edge off something mild :) I am a contrarian when it comes to most meds :blink: But I don't know of a connection to celiac.
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#7 T.H.

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Posted 05 October 2011 - 06:46 PM

Theoretically, it could contribute.

Celiacs don't just absorb nutrients properly, we can potentially not absorb meds properly as well, when we're undiagnosed. So some ingredients of the meds may be absorbing at different rates than they should, or in different amounts than they should, so they might be having different effects. The side effects might be more likely to occur if we're not absorbing the meds properly, possibly.

That said, my GI doc (he's the celiac go-to guy in my city) said that a much higher percentage of his patients with celiac disease seem to have more issues with medicine side effects. I know that myself, my daughter, and my grandmother (who we suspect had it) always get lots of bizarro side effects to medicines we've had to take.
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T.H.

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#8 mushroom

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Posted 05 October 2011 - 07:03 PM

Theoretically, it could contribute.

Celiacs don't just absorb nutrients properly, we can potentially not absorb meds properly as well, when we're undiagnosed. So some ingredients of the meds may be absorbing at different rates than they should, or in different amounts than they should, so they might be having different effects. The side effects might be more likely to occur if we're not absorbing the meds properly, possibly.

That said, my GI doc (he's the celiac go-to guy in my city) said that a much higher percentage of his patients with celiac disease seem to have more issues with medicine side effects. I know that myself, my daughter, and my grandmother (who we suspect had it) always get lots of bizarro side effects to medicines we've had to take.


Could be, although I would think (hope :o ) I am absorbing better now. Just had a "bizarro" summer where I was tried on lots of different meds and reacted to most of them in one way or another that meant I couldn't take them. I even reacted to meds (two antibiotics) I have tolerated fine before. The fewer meds I take the better :ph34r:
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Neroli


"Everything that can be counted does not necessarily count; everything that counts cannot necessarily be counted." - Albert Einstein

"Life is not weathering the storm; it is learning to dance in the rain"

"Whatever the question, the answer is always chocolate." Nigella Lawson

------------

Caffeine free 1973
Lactose free 1990
(Mis)diagnosed IBS, fibromyalgia '80's and '90's
Diagnosed psoriatic arthritis 2004
Self-diagnosed gluten intolerant, gluten-free Nov. 2007
Soy free March 2008
Nightshade free Feb 2009
Citric acid free June 2009
Potato starch free July 2009
(Totally) corn free Nov. 2009
Legume free March 2010
Now tolerant of lactose

Celiac.com - Celiac Disease Board Moderator

#9 pricklypear1971

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Posted 05 October 2011 - 07:38 PM

I'm one of those that overreacts. Recently to corticosteroids, antibiotics....,

Ironically I can drink coffee all night and go to sleep in a blink. But give me ONE EXCEDRIN....and I'm cleaning my room and reorganizing drawers with a 102+ fever.

I'm just weird.
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