Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Difference Between Ttg, Ema And Dgp?
0

6 posts in this topic

Does anyone here know the difference between TTG, EMA and DGP blood tests? I know they all assess the extent of tissue antibodies but don't assess the body's reaction to gluten.

0

Share this post


Link to post
Share on other sites


Does anyone here know the difference between TTG, EMA and DGP blood tests? I know they all assess the extent of tissue antibodies but don't assess the body's reaction to gluten.

I don't know off hand, but I would highly recommend getting a copy of Dr. Peter Green's book - Celiac Disease a Hidden Epedemic, he covers all of these tests in that book in a way that is easy for the reader to understand.

1

Share this post


Link to post
Share on other sites

I don't know off hand, but I would highly recommend getting a copy of Dr. Peter Green's book - Celiac Disease a Hidden Epedemic, he covers all of these tests in that book in a way that is easy for the reader to understand.

Some of us know just fine off hand. She doesn't need to go buy a book!

Does anyone here know the difference between TTG, EMA and DGP blood tests? I know they all assess the extent of tissue antibodies but don't assess the body's reaction to gluten.

TTG is an antibody against tissue transglutaminase, an enzyme involved in tissue repair. It is autoimmune and while the most common cause of anti-TTG is celiac, it can appear in rheumatoid arthritis, autoimmune liver disease, and inflammatory bowel disease as well. (There may be others; that list is off the top of my head.)

Anti-EMA is an autoantibody against endomysium, a type of connective tissue. Anti-EMA is HIGHLY specific for celiac disease.

DGP is an antibody against deamidated gliadin peptide (DGP), a fragment of gluten that has been processed in the intestine by TTG. It is not an autoantibody, but DGP is only produced in individuals with celiac so it's 100% specific for celiac disease.

0

Share this post


Link to post
Share on other sites
Some of us know just fine off hand. She doesn't need to go buy a book!

Actually, that book should be required reading by everyone with a gluten problem. It is full of excellent information that would benefit many.

Then we wouldn't have people being scared by those who think there is gluten in vegetables! Or that everything is contaminated with gluten! :blink:

1

Share this post


Link to post
Share on other sites

That's interesting that DGP is definitive for celiac. Can you reference that? The reason I ask is I had all the testing, and all the labs were normal except DGP, which was 4x the upper limit. I've had two separate biopsies and both were negative. I have mega-stomach issues with bloating and constipation. So, I've always wondered if I really am celiac due to that one test. Of course, the doctors tell me no because of the negative biopsies. I just began gluten-free yesterday.

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0