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Steroid Use (Even Topical) And Testing


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#1 domesticactivist

 
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Posted 19 December 2011 - 09:20 AM

We got follow up testing done for our son, since he's been gluten-free for over a year now, and the lab sent us back info I'd never seen before!

We actually got this on the sample submission guidelines for celiac testing from a different lab, to which we were submitting samples for something else (instructions in the same booklet). The instruction book had this info in it. The lab results from the celiac testing (at another lab, submitted by our doctor) did not say anything about this.

Did you know that steroid use, even topical use a month prior, can cause false negatives on celiac testing?

"Immunosuppressive drugs such as oral or intranasal corticosteroids (prednisone, beclomethasone, fluticasone, triamcinolone), and topical cortisone suspensions and creams, may affect test results for antibody assessment. The suggested time period to abstain from these is 4 weeks."
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Our family is transitioning off the GAPS Intro Diet and into the Full GAPS Diet.
Gluten-Free since November 2010
GAPS Diet since January/February 2011
me - not tested for celiac - currently doing a gluten challenge since 11/26/2011
partner - not tested for celiac
ds - age 11, hospitalized 9/2010, celiac dx by gluten reaction & genetics. No biopsy or blood as we were already gluten-free by the time it was an option.
dd - age 12.5, not celiac, has Tourette's syndome
both kids have now-resolved attention issues.

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#2 pricklypear1971

 
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Posted 19 December 2011 - 09:51 AM

I found out a bit ago....

Makes me not regret trying to test, because I was pumped full of them at the time I went gluten-free.

So that's another one that should be out on the list of why tests come out negative - steroid use.
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Apparently there is nothing that cannot happen today. ~ Mark Twain

Probable Endometriosis, in remission from childbirth since 2002.
Hashimoto's DX 2005.
Gluten-Free since 6/2011.
DH (and therefore Celiac) dx from ND
.
Responsive to iodine withdrawal for DH (see quote, above).

Genetic tests reveal half DQ2, half DQ8 - I'm a weird bird!

#3 domesticactivist

 
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Posted 19 December 2011 - 09:53 AM

Yeah, I was shocked to learn it since I hadn't seen it mentioned here and no doctor ever said anything about that. Last year I finally convinced a friend (with family history and clear symptoms) to get her daughter tested and it came back negative... she's been on steroids for ages for her skin!
  • 0
Our family is transitioning off the GAPS Intro Diet and into the Full GAPS Diet.
Gluten-Free since November 2010
GAPS Diet since January/February 2011
me - not tested for celiac - currently doing a gluten challenge since 11/26/2011
partner - not tested for celiac
ds - age 11, hospitalized 9/2010, celiac dx by gluten reaction & genetics. No biopsy or blood as we were already gluten-free by the time it was an option.
dd - age 12.5, not celiac, has Tourette's syndome
both kids have now-resolved attention issues.

#4 pricklypear1971

 
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Posted 19 December 2011 - 09:54 AM

Yeah, I was shocked to learn it since I hadn't seen it mentioned here and no doctor ever said anything about that. Last year I finally convinced a friend (with family history and clear symptoms) to get her daughter tested and it came back negative... she's been on steroids for ages for her skin!


Yep. I'd think "rashy" people are at particular risk of testing negative.
  • 0
Apparently there is nothing that cannot happen today. ~ Mark Twain

Probable Endometriosis, in remission from childbirth since 2002.
Hashimoto's DX 2005.
Gluten-Free since 6/2011.
DH (and therefore Celiac) dx from ND
.
Responsive to iodine withdrawal for DH (see quote, above).

Genetic tests reveal half DQ2, half DQ8 - I'm a weird bird!




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