Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Celiac Vs Intolerance + G6Pd
0

12 posts in this topic

Wasn't sure where to post this so sorry if it's the wrong board.

I've been trying to read more about Gluten Intolerance, and whether there's a difference between it and Celiac but couldn't find a good answer. Anyone know of a good web site explaining that or could try explaining here?

I also just found out I have G6PD, but not sure how much it's effecting me yet (might just be a carrier). Anyone else here who has G6PD symptoms and celiac? How do you cope without beans and soya?

0

Share this post


Link to post
Share on other sites


Ads by Google:

Yes, there is a difference. There's also wheat allergies.

Pretty much, non-celiac gluten intolerance doesn't cause the same damage to the small intestines that celiac disease does.

There hasn't been enough research on NCGI, although there has been a push for more research to be done on it.

Regardless, a gluten-free diet is the current answer (or a wheat-free in the case of wheat allergies.)

0

Share this post


Link to post
Share on other sites

Yes, there is a difference. There's also wheat allergies.

Pretty much, non-celiac gluten intolerance doesn't cause the same damage to the small intestines that celiac disease does.

There hasn't been enough research on NCGI, although there has been a push for more research to be done on it.

Regardless, a gluten-free diet is the current answer (or a wheat-free in the case of wheat allergies.)

So people with NCGI are able to absorb nutrients but just can't tolerate gluten?

0

Share this post


Link to post
Share on other sites

So people with NCGI are able to absorb nutrients but just can't tolerate gluten?

Not always. You also have to factor in celiacs who show up with a false negative on blood tests, they are usually labeled NCGI. I am a celiac who had years of false negative blood tests so some might consider me NCGI (my doctors consider me diagnosed as celiac) and you can see the damage that was done in my signature.

0

Share this post


Link to post
Share on other sites

So people with NCGI are able to absorb nutrients but just can't tolerate gluten?

Yes, typically.

There are plenty of undiagnosed people, of course. With both NCGI and Celiac.

0

Share this post


Link to post
Share on other sites




Morning.

I've been doing more reading of the research studies that are coming out in gluten sensitivity/NCGI. They point to that the antibodies that are created in response to gluten attack other parts of the body, like the brain, not (just) the intestine. It also seems to involve a different immune response: NCGI respond with the innate immunity and Celiacs respond with adaptive immunity which is more specific.

"In the new study, researchers compared blood samples and intestinal biopsies from 42 subjects with confirmed celiac disease, 26 with suspected gluten sensitivity and 39 healthy controls. Those with gluten sensitivity didn't have the flattened villi, or the "leaky" intestinal walls seen in the subjects with celiac disease.

Their immune reactions were different, too. In the gluten-sensitive group, the response came from innate immunity, a primitive system with which the body sets up barriers to repel invaders. The subjects with celiac disease rallied adaptive immunity, a more sophisticated system that develops specific cells to fight foreign bodies."

http://online.wsj.com/article/SB10001424052748704893604576200393522456636.html

..and I would agree with Ravenwoodglass. The medical profession (well, researchers anyway :P ) seem to just be beginning to stumble on evidence on the whole spectrum of how gluten affects the body and there isn't a rigid, one size fits all explanation.

0

Share this post


Link to post
Share on other sites

Thank you for posting that link. I remember years ago someone had said their grandfather seemed to fit Celiac diagnoses. When the grandfather died they did an autopsy, and found damage to the outside of the intestines. Doctors had to rethink the Celiac diagnoses.

You should never get the impression that gluten intolerance isn't as serious as Celiac. The body is being harmed by gluten.

1

Share this post


Link to post
Share on other sites

Thanks for the insight everyone. I tried reading about NCGI but couldn't find anything definitive so thought I'd ask here. Was the right thing to do :-)

Makes me wonder which category my family falls under. My dad has diabetes, thyroid problems, joint inflammation, chronic constipation, and rashes, but he's tall, overweight and has thick bones.

I'm not officially diagnosed myself but I'm positive all my issues are caused by gluten through trial and error. No doctor has taken me seriously so I'm not sure I can get an official diagnosis, specially since it would be too hard for me to go back to eating gluten.

0

Share this post


Link to post
Share on other sites

So people with NCGI are able to absorb nutrients but just can't tolerate gluten?

My understanding is that chronic intestinal inflammation is enough to cause some degree of malabsorption. It doesn't take total villous atrophy. People with Crohn's and ulcerative colitis typically have high fecal fat and can have vitamin deficiencies. My mom is NCGI, negative blood & biopsy, and has been B12 deficient for years. She also has borderline anemia, poor bone density, and did not digest fats well until she went off gluten. I don't think you typically see the profound malabsorption that leads to wasting in NCGI though.

As far as understanding celiac vs. NCGI, Fasano just wrote a brand-new review article and it's available for free.

http://www.ncbi.nlm.nih.gov/pubmed/22313950

0

Share this post


Link to post
Share on other sites

As far as understanding celiac vs. NCGI, Fasano just wrote a brand-new review article and it's available for free.

http://www.ncbi.nlm.nih.gov/pubmed/22313950

Skylark! You are a peach! That link/research article is fantastic. Thank you very much.

:)

0

Share this post


Link to post
Share on other sites

Glad it was helpful. I'm awfully happy to have someone as good as Fasano working on celiac and NCGI!

0

Share this post


Link to post
Share on other sites

I don't think you typically see the profound malabsorption that leads to wasting in NCGI though.

This is probably true, yet my daughter is NCGI (although they refused biopsy due to negative blood work and no genes) and she is off the growth charts (less than zero percentile). They don't think she has ulcerative colitis or Crohn's. I think it is the gluten but we will see. Her hair is starting to grow in and her skin tone went from gray to pink in 6 weeks.

Because of Dr. Fasano's work, I think NCGI will bust wide open within the next few years. I just hope it isn't the "disease du jour", like IBS was. It would be nice to have definitive testing for it. Probably a pipe dream.

To the OP, good luck on your journey to better health.

1

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,678
    • Total Posts
      921,703
  • Topics

  • Posts

    • At the moment it's microwave rice packets as it needs to be something easy for lunch at work. What do you choose for breakfast? At the moment I have gluten-free porridge oats with fruits but also seeing oats are a bit of a gamble in the early days. Trying to figure out how long a reaction takes to show up i.e. if I feel ropey later in the day is it really lunch as I'm blaming at present or actually is it something from the morning or even night before? The food is the toughest bit for me right now; wasn't that great with it before so will need plenty ideas from you good people... seems I'm in the right place though   
    • I know what you're going through - it's that grieving process and it's tough.  I was diagnosed in 2013, and aside from an occasional pity party, I don't look back. I have my restaurants where I feel safe, I have the food I know I can eat, and I get on with my life.  I'm lucky that I live in a big city with lots of options, but you can make this work, and you will feel better and once you do, you'll stop grieving.  The people on this site helped enormously. It is tough in the beginning to know if you've been 'glutened' vs. just going through withdrawal.  For that reason alone, it's best to avoid restaurants for a little while and be careful at home - just to be sure what's happening.  Eventually you'll be able to get back to your version of 'normal'.  Oh, I also have hypothyroid/hashimoto's.  No big deal, I take synthroid. Quinoa, eggs, nuts and beans for protein.  You don't have to go crazy on the cooking.  Just eat a lot of whole foods.  There are a lot of complicated recipes out there, but now may not be the time.  Rice noodles in veggie bouillon - easy and cheap.  gluten-free pasta with olive oil, parmesan and garlic - easy.  I eat a lot of rice and have never had a problem - you're not getting it out of one of those bulk bins, are you?  That could be contaminated.  Go with packaged.  Do you have access to the Macro Vegetarian brand of prepared rice dishes (in the refrigerated section).  They have several that are gluten free, they're delicious heated and with a little gluten-free soy sauce.  They're my go to on days I don't want to cook. Good luck!  
    • I also think that the HPV/Gardasil vaccine triggered something in my body. I had some Celiac symptoms many years before this vaccine but I felt ok. I was physically very active. However, after I received the third dose as well, I began having more problems including a more persistant pain, overall body weakness, lack of concentration, hair loss, etc.
    • OK so been to the doctor, they've sped up my referral and I should get the appointment booking form in the post shortly. They've said stay off the gluten until I have a date for the appointment then in the weeks leading up to it go back on - thoughts? Did my bit of sport last night which was a great relief to be free of any illness-related thoughts for an hour or two; didn't think I'd have the energy at the start but soon got going and was OK so that's a plus I seem to be getting some strange symptoms at the moment that have only happened since trying to remove gluten, do these sound familiar to anyone? dry forehead, just starting to go red \ itchy in places. Treating with E45-type cream tender scalp and sides of head, almost like a pulling feeling and a bit sensitive to touch. Scared this one matches the symptoms of GCA, a particularly nasty autoimmune disease that can lead to blindness 
      Edit: having said that just found this thread and funny enough did wash my hair this morning...
      http://www.celiac.com/gluten-free/topic/50920-sores-on-scalp/ one eye watering and associated fuzzy vision at times, trying to reassure myself it isn't blurred vision due to the point above sometimes bit of a lump in throat sensation, seems to come and go Been reading that some people can't handle rice - I was OK with it whilst eating gluten but have been having it for lunch each day and seem to get worse around 4-5pm so could that be a culprit? How long after coming off gluten would I be able to say I'm at a baseline to know if feeling ill is down to "glutening" vs. blaming it on the body adjusting to the change in (lack of) gluten in food?
    • First of all, welcome to the forum! it's good to have you here. Secondly, I can really relate to the fatigue portion.  it really hadn't affected me until everything hit the ceiling medically for me.  I was constantly tired all the time, and waking feeling rested in the morning. Prone to depression and anxiety, definitely.  It drove me nuts for those first few weeks.  That's when I decided to try going off the gluten to see what happened.  I still dealt with the depression, anxiety at crazy levels, and inability to focus/concentrate, but it had gotten progressively better.  The anxiety got so bad I would have panic attacks in public areas which only ramped up the anxiety because people saw what was happening.  I would encourage you and your doctor to do a full Celiac panel before you decide to try the gluten free diet.  I had my blood work done after I was off gluten for about two months or so.  Thankfully, my levels were still high to register at least a gluten sensitivity.  Since going off gluten for almost a year now, things have started to finally appear "normal".  Whatever normal means for me now.  As I am healing from the 30 years of glutenizing, I combined both natural methods with the medical methods.  If you are interested in the different avenues of natural methods, I would be willing to share with you.  I will be praying for you as you go through this journey. Let me assure you, you are not alone in this journey.  Depending on family dynamics, they can be a great source of support.  This forum is also a great place to bounce thoughts or concerns off of.  Good luck.
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,675
    • Most Online
      3,093

    Newest Member
    JVerg11
    Joined