I had a visit with my PCP today and she want's to run more blood work on me. I brought the L-Glutamine bottle with me and told her it had been connected with abnormal liver blood tests, but that I'd stopped taking it and wanted to wait a few months before re-testing. She told me in 15 years she'd never seen a connection and that I could have Hepatitis with those lab results. I stuck to my guns, rightly or wrongly, and wouldn't agree to the blood draw today. I don't have history of habits/behavior that would lead to Hepatitis or Liver Disease.
After I left my Dr's office visit, I googled L-Glutamine and Liver disease and came up with a 10 page report from England that you may find interesting:
1 TOX/2008/35 COMMITTEE ON TOXICITY OF CHEMICALS ...
I've had some wonky blood test results, but never had skewed results on a basic blood test. I can't say for certain it's from taking that supplement, but can say for certain I'm not taking it anymore.
Not to make you feel whatever--please note that the article you referred us to is about chondroitin and glucosamine sulfate. Not L-glutamine...
Nevertheless, whereas many thought there were no problems with it whatever, apparently that just ain't true. Too much of even a good thing, even if it just means taking it for too long, is still too much.
For me though, like it appears to be for you for your liver values, I was right to go off it. I do have a history of kidney problems and food allergies up the yin yang, especially to dyes, as well as hypoglycemia, which is a real no no for L-glutamine it appears.
Its too bad, since I did like how it made me feel, at least for a while. For most I think its OK though for a few days if one has just been glutened, or one has started a real work out program you aren't used to yet.
Meanwhile I am glad this discussion has helped you deepen an important clue for your health concerning the pros and cons of taking L-glutamine or not.
I want to point out though that many here with celiac do have damaged livers simply because of the toxic overload due to ourvilli being damaged and thus causing leaky gut. This in turn makes seemingly innocuous food substances like oil, proteins and carbohydrates etc. turn into foreign invaders that we react to. Downwind the liver has to clean upthemess and often gets clogged up and overloaded.
It might be wise to eat less animal fat for now for instance to take the stress off your liver. I find it is helping me after discovering my liver and gall bladder were stressed this last fall. It has helped to use a variety of detox herbs as well as eat more azuki and other beans and avoid butter and eggs and most meat except fish. I also now eat apples and pears most every day since theliver apparently loves them. The pectin in them helps detox the liver too.
After three months of that diet without meat except for fish, I now can eat chicken without the fat, and often cook a bit in with my beans and veggies. The azuki beans actually help dissolve the built up cholesterol in the liver and gall bladder. You can find t hem at most Asian stores.
By soaking the beans a good 24 to 48 hours, changing the water several times, and then bringing the new water to a boil and changing it another 3 times (boiling each time after and then straining the hot water out), before cooking the beans the final couple of hours, it helps get rid of the indigestible carbohydrate. I never thought I could eat beans before but find the azuki beans easy to digest. You might not need to go to such lengths, however I really seem to need to. If eaten with brown rice it increases the protein content of the beans according to many sources.
If you want documentation, please let me know. However you can Google a lot of this information yourself... Including the bit about the healing properties of azuki beans as well as the fact many celiacs have problems with their liver and gall bladder. The why of it is a little harder to trace, but out there if you do some sleuthing. I looked all this up with the help of my bf (who has more official medical training than I) due to my own condition and did not necessarily keep track of all the urls, though do have some.
Diagnosed celiac sprue as infant: failure to thrive & pneumonia-back on grains age 4. Began herbs 1971 combating chronic kidney disease/general ill health 1973. Avoid wheat family and "allergens" by 1980. Late 80's doc. diagnosed candida: cave-man diet. Diagnosed degraded myelin sheath 2006; need co-enzyme B vitamins. Discovered celiac fall 2007; finally told diagnosis as infant. Recently found I am salicylic acid intolerant. Ironically can't tolerate most herbs now. Can now eat brown rice & other gluten-free grains (except corn) & even maple syrup & now homeopathic medicine works! Am still exploring the shape of this elephant but I've made progress!