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Synthroid


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#1 Blueanj

 
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Posted 29 April 2012 - 09:54 AM

What's the deal with Synthroid? I'm on .025 mg and have just read it may contain gluten? Does it contain dairy? I don't tolerate dairy or gluten and am concerned. Are any thyroid meds gluten and dairy free?
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#2 a1956chill

 
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Posted 29 April 2012 - 10:19 AM

What's the deal with Synthroid? I'm on .025 mg and have just read it may contain gluten? Does it contain dairy? I don't tolerate dairy or gluten and am concerned. Are any thyroid meds gluten and dairy free?

Synthroid Description

Synthroid (levothyroxine sodium tablets, USP) contain synthetic crystalline L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland. Levothyroxine (T4) sodium has an empirical formula of C15H10I4N NaO4• H2O, molecular weight of 798.86 g/mol (anhydrous), and structural formula as shown:
Inactive Ingredients

Acacia, confectioner's sugar (contains corn starch), lactose monohydrate, magnesium stearate, povidone, and talc. The following are the color additives by tablet strength:
Strength (mcg) Color additive(s)
25 FD&C Yellow No. 6 Aluminum Lake*
50 None
75 FD&C Red No. 40 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake
88 FD&C Blue No. 1 Aluminum Lake, FD&C Yellow No. 6 Aluminum Lake*, D&C Yellow No. 10 Aluminum Lake
100 D&C Yellow No. 10 Aluminum Lake, FD&C Yellow No. 6 Aluminum Lake*
112 D&C Red No. 27 & 30 Aluminum Lake
125 FD&C Yellow No. 6 Aluminum Lake*, FD&C Red No. 40 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake
137 FD&C Blue No. 1 Aluminum Lake
150 FD&C Blue No. 2 Aluminum Lake
175 FD&C Blue No. 1 Aluminum Lake, D&C Red No. 27 & 30 Aluminum Lake
200 FD&C Red No. 40 Aluminum Lake
300 D&C Yellow No. 10 Aluminum Lake, FD&C Yellow No. 6 Aluminum Lake*, FD&C Blue No. 1 Aluminum Lake

*Note – FD&C Yellow No. 6 is orange in color.




My pharmacists will not state my synthroid is gluten free because of possible cross contamination issues.

I use name brand synthroid with no problems ,I can not use the generic alternative

, but I am not super sensitive to gluten. I am how ever super, SUPER sensitive to soy ( but that is another topic)
Another thing to consider are you having issues with corn??
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Gluten free Oct/09
Soy free Nov/10

numerous additional intolerances,, i.e. If it tries to kill me I do not eat it .
After 40+ years of misdiagnoses I was diagnosed with:
Dermatitis Herpetiformis : Positive DH biopsy...... Celiac :based on DH biopsy and diet response.

Osteoporosis before  age 50
Hashimoto's thyroiditis disease .

Diagnosed type 2 Diabetes 

Osteoarthritis

Gilbert's Syndrome , confirmed by gene testing


#3 Blueanj

 
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Posted 29 April 2012 - 10:37 AM

Synthroid Description

Synthroid (levothyroxine sodium tablets, USP) contain synthetic crystalline L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland. Levothyroxine (T4) sodium has an empirical formula of C15H10I4N NaO4 H2O, molecular weight of 798.86 g/mol (anhydrous), and structural formula as shown:
Inactive Ingredients

Acacia, confectioner's sugar (contains corn starch), lactose monohydrate, magnesium stearate, povidone, and talc. The following are the color additives by tablet strength:
Strength (mcg) Color additive(s)
25 FD&C Yellow No. 6 Aluminum Lake*
50 None
75 FD&C Red No. 40 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake
88 FD&C Blue No. 1 Aluminum Lake, FD&C Yellow No. 6 Aluminum Lake*, D&C Yellow No. 10 Aluminum Lake
100 D&C Yellow No. 10 Aluminum Lake, FD&C Yellow No. 6 Aluminum Lake*
112 D&C Red No. 27 & 30 Aluminum Lake
125 FD&C Yellow No. 6 Aluminum Lake*, FD&C Red No. 40 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake
137 FD&C Blue No. 1 Aluminum Lake
150 FD&C Blue No. 2 Aluminum Lake
175 FD&C Blue No. 1 Aluminum Lake, D&C Red No. 27 & 30 Aluminum Lake
200 FD&C Red No. 40 Aluminum Lake
300 D&C Yellow No. 10 Aluminum Lake, FD&C Yellow No. 6 Aluminum Lake*, FD&C Blue No. 1 Aluminum Lake

*Note FD&C Yellow No. 6 is orange in color.




My pharmacists will not state my synthroid is gluten free because of possible cross contamination issues.

I use name brand synthroid with no problems ,I can not use the generic alternative

, but I am not super sensitive to gluten. I am how ever super, SUPER sensitive to soy ( but that is another topic)
Another thing to consider are you having issues with corn??



I have just begun to suspect corn. I ate corn in two meals yesterday with black beans. At first I thought my distention, bloating, cramping and gas were due to beans...but then I got to thinking about the corn. I am also going to eliminate coffee, as I read it has a similar structure in protein to gluten. Without corn and coffee, I hope it all stops. I am tired of the daily onslaught of gas/bloating from 3:00 til bedtime. It's less without gluten, but still there. Now that I know what it feels like to feel good - I can't stand when I feel bad! I know synthroid has corn...do any of them not have corn, gluten or dairy? Can hashimoto's resolve if these intolerances are removed? My thyroid issue is very small compared to others' and I'm on a very low dosage. Thanks for your help. I really appreciate having a place to ask questions b/c doctors seem to know a little about a lot but not tons about everything.
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#4 a1956chill

 
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Posted 29 April 2012 - 11:23 AM

[quote name='Blueanj' timestamp='1335724651' post='791982'] Can hashimoto's resolve if these intolerances are removed? [quote]



There is a HUGE connection between cliacs and hashimotos. If I had not already been gluten free my endocrinologist would have put me on a gluten free diet when I was diagnosed with Hashimotos .



Personalty ,I do not know that being gluten free will resolve your hashimotos but it certainly can not hurt.
  • 0

Gluten free Oct/09
Soy free Nov/10

numerous additional intolerances,, i.e. If it tries to kill me I do not eat it .
After 40+ years of misdiagnoses I was diagnosed with:
Dermatitis Herpetiformis : Positive DH biopsy...... Celiac :based on DH biopsy and diet response.

Osteoporosis before  age 50
Hashimoto's thyroiditis disease .

Diagnosed type 2 Diabetes 

Osteoarthritis

Gilbert's Syndrome , confirmed by gene testing


#5 ravenwoodglass

 
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Posted 29 April 2012 - 12:35 PM

. I am also going to eliminate coffee, as I read it has a similar structure in protein to gluten.


Coffee will not gluten you. If you are newly diagnosed it may be too much for your stomach but that is not a gluten issue. Coffee is safe.
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Courage does not always roar, sometimes courage is the quiet voice at the end of the day saying
"I will try again tommorrow" (Mary Anne Radmacher)


celiac 49 years - Misdiagnosed for 45
Blood tested and repeatedly negative
Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002
Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis
All bold resoved or went into remission with proper diagnosis of Celiac November 2002
Some residual nerve damage remains as of 2006- this has continued to resolve after eliminating soy in 2007

Mother died of celiac related cancer at 56
Twin brother died as a result of autoimmune liver destruction at age 15

Children 2 with Ulcers, GERD, Depression, , 1 with DH, 1 with severe growth stunting (male adult 5 feet)both finally diagnosed Celiac through blood testing and 1 with endo 6 months after Mom


Positive to Soy and Casien also Aug 2007

Gluten Sensitivity Gene Test Aug 2007
HLA-DQB1 Molecular analysis, Allele 1 0303

HLA-DQB1 Molecular analysis, Allele 2 0303

Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)

#6 Skylark

 
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Posted 29 April 2012 - 01:46 PM

I know synthroid has corn...do any of them not have corn, gluten or dairy?

Tirosint

http://tirosintgelca...x.php?page=home
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#7 Blueanj

 
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Posted 07 May 2012 - 05:08 PM

Update on rash/synthroid:

I took out coffee, and most of the gas/bloating disappeared, but it reappeared heavily when I had Claritin D. Today, the rash on the back of my legs flared for the third time, with no suspicious foods/allergy meds present. I also got the same rash on my wrists, forearm and upper thighs in addition to the back of my knees. It burned so badly, I called the endocrinologist to see if it was a reaction to synthroid apart from gluten issues.

He said, "Oh, you're on synthroid? That has gluten in it. We always do Tirosint for our gluten patients." Abbott told me they don't test for gluten, but the people who make the ingredients say no gluten ingredients are used, but they can't say it's gluten-free.Anyway, back to the endo. You'd think they would have thought of this before. Anyway, they will give me Tirosint starting Weds. morning, so one more day of synthroid. But I'm heading to the dermatologist Weds. a.m. to have a biopsy done of the rash to see if I have a true celiac issue- DH.

I'm hoping this new med resolves the indigestion. I'm tired of it and working so hard to be gluten-free 100%!!!

Thanks to all who helped with this.
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#8 MaryJones2

 
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Posted 08 May 2012 - 02:58 PM

Synthorid is gluten free. You should consider it a myth that any thyroid medication contains gluten until proven otherwise. About 80% of my endo's patients are celiac or gluten sensitive and he's never once mentioned that Synthorid contains gluten and has prescribed it to me when Armour isn't available.

Many pharmacutial companies will not guarantee a medication is gluten free but Synthroid does not contain ANY gluten ingredients. There are many, many people on this board taking Synthoid and generic equivilents without issues. Many medications have additives (like blueanj mentioned here) and I am sensitive to dyes - that could be your issue or it could be the corn starch as you said.

If you continue to have issues you can try a natural version like Armour or have it made for you at a compounding pharmacy (I've used this one in the past when there was an Armour shortage - http://www.wellnesshealth.com/)

BTW - This site is invaluable when researching drugs. Bookmark it because it's hard to find: http://www.accessdat...atfda/index.cfm You can find the prescribing sheets and active and inactive ingredients for the name brand and generic equivilent (even by manufacturer) - click on theraputic equivilent on the page for the name brand to see a list of all of the manufacturers who make generics.

Good luck! Things will get better for you. It's always difficult in the beginning to figure out exactly what is causing things and as you heal things will bother you less. :)
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