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Test Results Help


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4 replies to this topic

#1 Caeryn23

 
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Posted 12 July 2012 - 07:44 AM

I wasn't sure where to post this. I have been off gluten for about 2 years. I still have GI issues. I was hospitalized in 1/12 and 6/12 for GI issues. Here are some recent tests.

My CT scan: "thickening of the distal tranverse colon...descending colon and rectum... consistent with colitis." It also shows a lot of stool burden. There was also thickening seen on a 2007 CT scan.

My colonoscopy: the descending colon mucosa is "erythematous, hemorrhagic, ulcerated, and to show loss of vascular markings suggestive of stercoral ulcers due to constipation." Four biopsies were taken. There also was inflammation seen on a 2007 colonoscopy.

My path report.
Descending colon, biopsy:
- Colonic mucosa with edema and hemorrhage
- No evidence of ischemic injury, inflammatory bowel disease or active inflammation.

I also have elevated SED Rate and Lactoferrin.

I don't think any of this is related to Celiac. But, what would these results indicate? The inpatient doctors said I had "end stage constipation." Has anyone heard of this? They said to take Miralax as a bowel regimen. Something must be causing my constipation/GI issues.

Thank you.
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#2 kmwondering

 
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Posted 14 July 2012 - 09:34 AM

I'm no doctor but a quick consult with Dr. G(oogle) indicates that these results might be associated with an inflammatory bowel disease...ulcerative colitis or crohns. Good luck with everything and I hope you get answers and relief.
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#3 beachbirdie

 
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Posted 14 July 2012 - 10:46 AM

I wasn't sure where to post this. I have been off gluten for about 2 years. I still have GI issues. I was hospitalized in 1/12 and 6/12 for GI issues. Here are some recent tests.

My CT scan: "thickening of the distal tranverse colon...descending colon and rectum... consistent with colitis." It also shows a lot of stool burden. There was also thickening seen on a 2007 CT scan.

My colonoscopy: the descending colon mucosa is "erythematous, hemorrhagic, ulcerated, and to show loss of vascular markings suggestive of stercoral ulcers due to constipation." Four biopsies were taken. There also was inflammation seen on a 2007 colonoscopy.

My path report.
Descending colon, biopsy:
- Colonic mucosa with edema and hemorrhage
- No evidence of ischemic injury, inflammatory bowel disease or active inflammation.

I also have elevated SED Rate and Lactoferrin.

I don't think any of this is related to Celiac. But, what would these results indicate? The inpatient doctors said I had "end stage constipation." Has anyone heard of this? They said to take Miralax as a bowel regimen. Something must be causing my constipation/GI issues.

Thank you.


I'm confused by the report. Elevated Lactoferrin does point to inflammation and inflammatory bowel disease, and the SED rate is also an idicator of inflammation. Have they tested you for bacterial overgrowth?

Stercoral ulcers (I had to Google that one!) ARE a result of chronic constipation. And they can be dangerous, so you need to take them seriously.

What is your diet like? Do you eat much in the way of fruits and vegetables?

Are you certain you are not getting gluten in your diet anywhere? Have they done any follow-up blood tests to see if you have any celiac antibodies?

Are you active, these ulcers seem to happen more in sedentary people.
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1999 - Hypothyroid
2003 - Hashimoto's Disease
2008 - Diverticulitis
2009 - Significant Vit D Deficiency
2011 - Diverticulitis again
2011 - HLA-DQ2.2
2012 - TtG IgG positive... I am now, finally, Gluten Free - 5/16/2012

#4 Caeryn23

 
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Posted 14 July 2012 - 01:39 PM

Than you for responding. I have not been tested for bacterial overgrowth. The doctors said the high lactoferrin and sed rate are "nonspecific." I don't know why they ordered them then.

They said the ulcers will heal on their own. The only thing the doctors said was to take Miralax. I wasn't given any other treatment.

I'm some what active and eat fruits and veggies. I have food allergies, so I stay away from those foods. I don't think I am getting glutened. I try to be careful.

I had a celic panel in 2011. The EMA was not ran. Here are the results:
Anti-Gliadin Antibodies
IgG 3 and IgA 1
ranges: 0-19 negative, 20-30 weak positive, >30 moderate to strong positive

Tissue Transglutaminase Antibody IgA <2
ranges: 1-3 negative, 4-10 weak positive, >10 positive

Tissue Transglutaminase Antibody IgG <2
ranges: 0-5 negative, 6-9 weak positive, >9 positive

I have HLA DQ2, DQ8, DR4, and DR7.
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#5 razzle51

 
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Posted 07 January 2013 - 08:05 AM

forget the Mirlax omg got deathly ill from it... alot of other things ... are you the one on ASAP board
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