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I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?

Test Result Flag Reference Range

Immunoglobulin A, Qn, Serum 78 L 91-414

t-Transglutaminase (tTG) IgA >100 H 0-3

Negative 0-3

Weak Positive 4-10

Positive >10

Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.

Deaminated Gliadin Abs, IgA 53 H 0-19

Negative 0-19

Weak Positive 20-30

Moderate to Strong Positive >30

Edited by NStock
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I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?

Test Result Flag Reference Range

Immunoglobulin A, Qn, Serum 78 L 91-414

t-Transglutaminase (tTG) IgA >100 H 0-3

Negative 0-3

Weak Positive 4-10

Positive >10

Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.

Deaminated Gliadin Abs, IgA 53 H 0-19

Negative 0-19

Weak Positive 20-30

Moderate to Strong Positive >30

Quite positive, i say!

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Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.

Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it. :):(

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Your total IgA is low (you got a 78 when the normal range starts at 91). You might be IgA deficient.

Your tTg IgA is positive (you got over 100 when a positive is anything over 3).

Your deamidated IgA is positive (you got 53 when a positive is anything over 19).

Very positive results here.

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:( Yeah... not many people get a positive tTG IgA if their IGA is low. Your blood tests are very positive. Your doctor may or may not order a biopsy to confirm; not all doctors do it now a days. If he wants to biopsy, you'll have to decide if you want it or need it for a firm diagnosis. It is usually recommended that you continue eating gluten until you are sure all testing is complete.

When you see your doctor, you might want to have your nutrient levels checked. Sometimes, because of the intestinal damage, celiacs suffer from malabsorption of some key nutrients. B12, D, ferritin, calcium, potasium can end up being low causing osteoarthritis, anemia, and some other health problems; I think there are other nutients affected but I can't remember which at this time.

Best wishes. Hope you feel well soon.

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Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.

Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it. :):(

Alrighty... well thanks for the feedback. I'm pretty familiar with a gluten free diet. My Mom got diagnosed with the celiac disease in the 90s, so I'm hoping it'll be a fairly smooth transition.

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Cool well thanks for the feedback everyone... it'll be fun switching my entire diet haha... hopefully I have the self control to follow through because I love my gluten ; ) I know what damage it can do to not stick to the gluten free diet.

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    • I figured I would update those who were wondering.  I have gotten the appt. so far moved up to August 30. I am waiting to have gene testing done via swab for all 3 of my kiddos tomorrow. My daughters celiac antibodies came up negative but her IgA is low which the ped said could cause false negative antibodies for celiac so she will need to see a GI dr. also. The pediatrician is going to call the GI to try to get them in sooner. I am keeping them all on a gluten diet until the GI dr. decides what to do. I am on the cancellation list already for my son, however I am not going to be persistent with my phone calls to them until I have the results of the gene test. I really want that result in my hand before going to the GI dr if I can. Maybe if he is positive, along with his bloodwork and my history they can forgo the endoscopy. But he will eat gluten till then.  My husband and I have been very honest and upfront with him as to what is going on and the possibility of the endoscopy and what that entails and although scared in general he seems ok after assuring him that since I have it he has me to help him every step of the way.  Going through his current diet with him I realized that he is truly on such a low gluten diet that I am actually surprised his bloodwork shows antibodies at all!  So I told him to make a list of allllll the gluten he could possibly think of eating and he needs to pound it until the GI visit or endoscopy. Funny thing is everything he keeps thinking of to want to eat...is already gluten free!  The other night we were at a friends and he asked if he could be done with his hotdog. I made him finish just the bread 😂 Thanks for your help and advise and I will keep y'all posted on both kids!  My oldest is a ok as far as all his antibodies. Just actually had a follow up for other immune issues and all his levels are now normal!
    • I like your plan Cara, I may have to include it in my sons.    Poor little guy is still very very sick. I think he is resisting and cheating, despite having the support of two other siblings and a 100% gluten-free home. 
    • Despite it being a nightmare, I did wait for my kids to get biopsies. At one point I had one severely ill child gluten-free and two more waiting having to eat it. It was worth the wait though and I think long term a biopsy may be worthwhile, especially for school. I have already had issues with schools and camps so having a firm diagnosis has been helpful. 
    • Knowing that the reaction to gluten in celiacs is an uncalled for immune system reaction, I was thinking of how a cure would be possible. Maybe a medicine that somehow turns off the immune system. The only thing that i've heard do that... HIV.  obviously that's way worse than celiac. Just some food for thought.
    • Well, you can probably get an apple or something.  You might be able to get someone to boil you some eggs.  But be careful of things like nuts that should be naturally gluten free.  They have almost always been soaked in a flavor solution that usually containes caramel coloring, "soy" (wheat) sauce and other aditives.  If I am really hungry and must eat in a Chinese restaurant, I order plain white rice and steamed vegetables.  But even so, you must monitor it carefully.  The rice sometimes has other substances added to give it a better texture, and very often the vegetables have in fact had "just a little bit" of soy sauce added.  To be fair, celiac disease is hardly ever found in East Asians, so understandably people are not tuned it to it.  Also, culturally, with the exception of fruits, it is generally thought that the flavor of foods needs to be enhanced, so it is had to find anything natural even in the "western" gorceries. Even in the western restaurants, be careful.  Fish and meat and often vegetables are usually pre-marinated. I will not even attempt to address the issue of cross-comtamination, since that is a whole higher order of things. I do know what I am talking about; I have celiac and have worked here for nearly 7 years.  
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