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I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?

Test Result Flag Reference Range

Immunoglobulin A, Qn, Serum 78 L 91-414

t-Transglutaminase (tTG) IgA >100 H 0-3

Negative 0-3

Weak Positive 4-10

Positive >10

Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.

Deaminated Gliadin Abs, IgA 53 H 0-19

Negative 0-19

Weak Positive 20-30

Moderate to Strong Positive >30

Edited by NStock
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I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?

Test Result Flag Reference Range

Immunoglobulin A, Qn, Serum 78 L 91-414

t-Transglutaminase (tTG) IgA >100 H 0-3

Negative 0-3

Weak Positive 4-10

Positive >10

Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.

Deaminated Gliadin Abs, IgA 53 H 0-19

Negative 0-19

Weak Positive 20-30

Moderate to Strong Positive >30

Quite positive, i say!

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Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.

Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it. :):(

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Your total IgA is low (you got a 78 when the normal range starts at 91). You might be IgA deficient.

Your tTg IgA is positive (you got over 100 when a positive is anything over 3).

Your deamidated IgA is positive (you got 53 when a positive is anything over 19).

Very positive results here.

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:( Yeah... not many people get a positive tTG IgA if their IGA is low. Your blood tests are very positive. Your doctor may or may not order a biopsy to confirm; not all doctors do it now a days. If he wants to biopsy, you'll have to decide if you want it or need it for a firm diagnosis. It is usually recommended that you continue eating gluten until you are sure all testing is complete.

When you see your doctor, you might want to have your nutrient levels checked. Sometimes, because of the intestinal damage, celiacs suffer from malabsorption of some key nutrients. B12, D, ferritin, calcium, potasium can end up being low causing osteoarthritis, anemia, and some other health problems; I think there are other nutients affected but I can't remember which at this time.

Best wishes. Hope you feel well soon.

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Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.

Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it. :):(

Alrighty... well thanks for the feedback. I'm pretty familiar with a gluten free diet. My Mom got diagnosed with the celiac disease in the 90s, so I'm hoping it'll be a fairly smooth transition.

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Cool well thanks for the feedback everyone... it'll be fun switching my entire diet haha... hopefully I have the self control to follow through because I love my gluten ; ) I know what damage it can do to not stick to the gluten free diet.

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    • Hi Laurabella, Yes, you could have celiac disease!  It is important to keep eating gluten until all testing is completed, including an endoscopy with biopsy samples if the doctor recommends it.  The doctors usually do want the endoscopy.  The biopsy samples of the small intestine lining (4 to 6 samples) are checked for microscopic damage that indicates celiac disease.  Gall bladder problems can happen with celiac disease.  Your pain could also be from intestinal damage in any part of the small intestine. Some things you could try while you are waiting for your tests to be completed are stopping all dairy, and taking peppermint tea for gas in the stomach.  Celiac disease damage makes it hard to digest dairy sugar (lactose) and that can cause bloating and pain.  Constipation and diahrea are also possible fun symptoms. Welcome to the forum!
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