I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?
TestResultFlagReference Range
Immunoglobulin A, Qn, Serum 78 L 91-414
t-Transglutaminase (tTG) IgA >100 H 0-3 Negative 0-3 Weak Positive 4-10 Positive >10
Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.
Deaminated Gliadin Abs, IgA 53 H 0-19 Negative 0-19 Weak Positive 20-30 Moderate to Strong Positive >30
I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?
TestResultFlagReference Range
Immunoglobulin A, Qn, Serum 78 L 91-414
t-Transglutaminase (tTG) IgA >100 H 0-3 Negative 0-3 Weak Positive 4-10 Positive >10
Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.
Deaminated Gliadin Abs, IgA 53 H 0-19 Negative 0-19 Weak Positive 20-30 Moderate to Strong Positive >30
Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.
Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it.
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Neroli
"Everything that can be counted does not necessarily count; everything that counts cannot necessarily be counted." - Albert Einstein
"Life is not weathering the storm; it is learning to dance in the rain"
"Whatever the question, the answer is always chocolate." Nigella Lawson
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Caffeine free 1973 Lactose free 1990 (Mis)diagnosed IBS, fibromyalgia '80's and '90's Diagnosed psoriatic arthritis 2004 Self-diagnosed gluten intolerant, gluten-free Nov. 2007 Soy free March 2008 Nightshade free Feb 2009 Citric acid free June 2009 Potato starch free July 2009 (Totally) corn free Nov. 2009 Legume free March 2010 Now tolerant of lactose
Your total IgA is low (you got a 78 when the normal range starts at 91). You might be IgA deficient.
Your tTg IgA is positive (you got over 100 when a positive is anything over 3).
Your deamidated IgA is positive (you got 53 when a positive is anything over 19).
Very positive results here.
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Tiffanyaka "Have I Mentioned Chocolate Lately?" Inconclusive Blood Tests, Positive Dietary Results, No Endoscopy G.F. - September 2003; C.F. - July 2004 Hiker, Yoga Teacher, Engineer, Painter, Be-er of Me Bellevue, WA
Yeah... not many people get a positive tTG IgA if their IGA is low. Your blood tests are very positive. Your doctor may or may not order a biopsy to confirm; not all doctors do it now a days. If he wants to biopsy, you'll have to decide if you want it or need it for a firm diagnosis. It is usually recommended that you continue eating gluten until you are sure all testing is complete.
When you see your doctor, you might want to have your nutrient levels checked. Sometimes, because of the intestinal damage, celiacs suffer from malabsorption of some key nutrients. B12, D, ferritin, calcium, potasium can end up being low causing osteoarthritis, anemia, and some other health problems; I think there are other nutients affected but I can't remember which at this time.
Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.
Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it.
Alrighty... well thanks for the feedback. I'm pretty familiar with a gluten free diet. My Mom got diagnosed with the celiac disease in the 90s, so I'm hoping it'll be a fairly smooth transition.
Cool well thanks for the feedback everyone... it'll be fun switching my entire diet haha... hopefully I have the self control to follow through because I love my gluten ; ) I know what damage it can do to not stick to the gluten free diet.
Also tagged with one or more of these keywords: test results, celiac disease panel, test results interpretation, IgA results, Transglutaminase, gluten free