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I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?

Test Result Flag Reference Range

Immunoglobulin A, Qn, Serum 78 L 91-414

t-Transglutaminase (tTG) IgA >100 H 0-3

Negative 0-3

Weak Positive 4-10

Positive >10

Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.

Deaminated Gliadin Abs, IgA 53 H 0-19

Negative 0-19

Weak Positive 20-30

Moderate to Strong Positive >30

Edited by NStock
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I don't know how to interpret these lab results and my doctor isn't available for a few days to call. Anybody know what this means?

Test Result Flag Reference Range

Immunoglobulin A, Qn, Serum 78 L 91-414

t-Transglutaminase (tTG) IgA >100 H 0-3

Negative 0-3

Weak Positive 4-10

Positive >10

Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy.

Deaminated Gliadin Abs, IgA 53 H 0-19

Negative 0-19

Weak Positive 20-30

Moderate to Strong Positive >30

Quite positive, i say!

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Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.

Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it. :):(

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Your total IgA is low (you got a 78 when the normal range starts at 91). You might be IgA deficient.

Your tTg IgA is positive (you got over 100 when a positive is anything over 3).

Your deamidated IgA is positive (you got 53 when a positive is anything over 19).

Very positive results here.

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:( Yeah... not many people get a positive tTG IgA if their IGA is low. Your blood tests are very positive. Your doctor may or may not order a biopsy to confirm; not all doctors do it now a days. If he wants to biopsy, you'll have to decide if you want it or need it for a firm diagnosis. It is usually recommended that you continue eating gluten until you are sure all testing is complete.

When you see your doctor, you might want to have your nutrient levels checked. Sometimes, because of the intestinal damage, celiacs suffer from malabsorption of some key nutrients. B12, D, ferritin, calcium, potasium can end up being low causing osteoarthritis, anemia, and some other health problems; I think there are other nutients affected but I can't remember which at this time.

Best wishes. Hope you feel well soon.

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Your results are strongly positive. It is possible that they may (or may not) want to do the endoscopy with biopsies just to check what your level of damage is, and for that you still need to be eating gluten. Your doctor will probably refer you to a gastroenterologist for further work-up.

Welcome to the board, and you may as well start reading as much as you can about celiac and how to avoid gluten, because I would say you have it, and you willl have to do it. :):(

Alrighty... well thanks for the feedback. I'm pretty familiar with a gluten free diet. My Mom got diagnosed with the celiac disease in the 90s, so I'm hoping it'll be a fairly smooth transition.

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Cool well thanks for the feedback everyone... it'll be fun switching my entire diet haha... hopefully I have the self control to follow through because I love my gluten ; ) I know what damage it can do to not stick to the gluten free diet.

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    • I think the gene tests are accurate.  Not sure if thier interpretation of them is.   If you actually think have Celiac, you need to know that.  You  need to know how careful you must be.  You need a diagnosis to get gluten-free food in hospitals or nursing homes (if you can find one that does gluten-free food).  Because thsese "stool tests" are not medically accepted, it is unlikely that a real medical facility will consider you to have Celiac.   http://www.cureceliacdisease.org/faq/why-dont-you-recognize-tests-stool-tests-or-otherwise-for-gluten-sensitivity-that-are-currently-available-through-companies-like-enterolab-or-cyrex/
    • Why would your doctor order an endoscopy and check for celiac disease, but not order a celiac panel?  Had you been gluten free already?  
    • Thanks cyclinglady ... just wondering, do most of the people on this forum believe the Enterolab stool / gene testing to be non-trustworthy? Or are you just recommending a diagnosis from my MD so that she is also treating me with full belief/knowledge of my condition? I've been gluten free now for 2 weeks - by the time I get in to my doctor, she orders the bloodwork and I get to a lab it could be another 2 weeks before the bloodwork is done. From what I understand, just a month of gluten free eating could skew the results of the blood test. Supposedly, the stool tests are much more accurate. I hate to go backwards and start eating gluten again just so I can have a blood test done that may or may not substantiate the results of the stool / gene testing. I'm so confused ...
    • Try to stick to a whole foods diet.  Things like unseasoned stew, soup, etc.  Things easy-to digest, preferably not processed by a anyone except you.  Too often new celiacs start using gluten-free foods (cookies, bread, crackers).  Your body is not used to these grains and they often contain lots of junk.  For example, I react to Xantham gum.  It does not bother my gluten-free hubby, but it gets me every single time!   Did you read our Newbie 101 thread under "Coping"?   It contains lots of valuable tips.  Make sure those meds are gluten free.  Supplements too.   I hope you feel better soon!    
    • Here are the actual tests.   http://www.cureceliacdisease.org/screening/ Insist on the complete panel.  Let them know (your doctor) that your father had celiac disease.   Document in writing!  If you have celiac disease, your life can be improved.  All the things I attributed to aging were actually related to celiac disease.  It is never too late to feel well!  I am in my 50's but my Aunt iis 81.  We celebrate a Gluten free Thanksgiving every year!   Oh, my kid does not have celiac disease, but she is tested every few years even though she is symptom free!  There are silent celiacs.  My symptom?  Anemia.  No tummy issues.   Please advocate for your health.  Keep all records.  Doctors can not ignore written facts and requests.    
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