Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Thyroid "totally Looks Like" Gluten?
0

6 posts in this topic

Nerdchick at work again...

I keep coming across references to an alleged structural similarity between gluten and thyroid cells (the proteins that constitute the thyroid, I assume), which would explain why Hashimoto patients do better on a gluten-free diet regardless of having Celiac or not.

The rationale would be that when gluten enters the body, the antithyroid antibodies take gluten for an extra thyroid, freak out, and scream "OMG! There's ANOTHER ONE! We need more squads!" and the body increases the production of antibodies, and therefore the attack to the thyroid.

Can anyone point me to the medical source/study for this diffused claim? I am seeing my endo soon for a new set of tests, and I want something to torture her with... ;)

0

Share this post


Link to post
Share on other sites


Ads by Google:

Hm...I don't know about it looking like gluten. I have seen this page, where a guy talks about why the antibodies involved in celiac also attack the thyroid:

"I knew that attack on the thyroid was common in celiacs, because the celiac autoantigen tTG (it has a basic triplet) is also present in the thyroid and the celiac autoantibodies to tTG also cause an attack on the thyroid. But the autoantigen for Hashimoto’s Thyroiditis is thyroid peroxidase (TPO)."

http://coolinginflammation.blogspot.jp/2009/07/celiac-causes-allergies-and-autoimmune.html

It's a bit greek to me, but it seems like you might be onto something with your idea.

0

Share this post


Link to post
Share on other sites

The only autoimmune disease we know the trigger for is celiac disease. All the others are not known at this point. We do know that people with celiac have a higher chance of getting other auto-immune diseases. My own personal "hunch" is that leaky gut plays a role in that. Protein fragments get in the blood stream and can cause an immune reaction in various parts of the body where they end up. But that's just a guess, there is no proof of that. I don't think the thyroid looks like gluten tho, that seems like a stretch. The leaky gut idea would mean gluten protein fragments end up in the thyroid, and then are attacked by the immune system. Then the body attacks the thyroid tissue where those gluten protein fragments are lodged. Same basic process as in the gut. In the process of attacking the gluten fragments in the thyroid, the immune system may learn to attack the thyroid also. This kind of process could cause rhuematoid arthritis to develop also. That's my 2 cent theory for today.

0

Share this post


Link to post
Share on other sites

Nerdchick at work again...

I keep coming across references to an alleged structural similarity between gluten and thyroid cells (the proteins that constitute the thyroid, I assume), which would explain why Hashimoto patients do better on a gluten-free diet regardless of having Celiac or not.

The rationale would be that when gluten enters the body, the antithyroid antibodies take gluten for an extra thyroid, freak out, and scream "OMG! There's ANOTHER ONE! We need more squads!" and the body increases the production of antibodies, and therefore the attack to the thyroid.

Can anyone point me to the medical source/study for this diffused claim? I am seeing my endo soon for a new set of tests, and I want something to torture her with... ;)

Most organs in the human body have the ability to produce tTg antibodies. The thyroid, heart and liver are some, along with the pancreas. When you have undiagnosed Celiac, your body is in a constant state of inflammation. If you go long enough, this inflammation will aggravate other organs and they start to produce tTg antibodies. This is why when some people go gluten-free and still have elevated tTg antibodies, you need to be tested for other AI conditions. Elevated thyroid antibodies can keep your tTg levels high, even on the gluten-free diet. It took me 6 years to get my thyroid antibodies into the normal range and they were ridiculously high when diagnosed. I think that the problem stems from too much inflammation and the gluten-free diet brings inflammation way down so everything else begins to heal.

I did have a good laugh about torturing your endocrinologist, though! :lol:

0

Share this post


Link to post
Share on other sites

The only autoimmune disease we know the trigger for is celiac disease. All the others are not known at this point... My own personal "hunch" is that leaky gut plays a role in that. Protein fragments get in the blood stream and can cause an immune reaction in various parts of the body where they end up.

I second that - I do think there are triggers for other disorders as well. How does one diagnose leaky gut? I have found some contrasting information...

Elevated thyroid antibodies can keep your tTg levels high, even on the gluten-free diet. It took me 6 years to get my thyroid antibodies into the normal range and they were ridiculously high when diagnosed. I think that the problem stems from too much inflammation and the gluten-free diet brings inflammation way down so everything else begins to heal.

I did have a good laugh about torturing your endocrinologist, though! :lol:

Oh, she had to get used to my paranoia :) I am wondering if the gluten-free diet also reduces inflammation/tTg in patients who have not been diagnosed with celiac disease, though... I don't know what my next thyroid panel going to find (to be true, I am scared of finding out) but, in short, if there is anything I can do to prevent/delay the distruction of a vital organ, well, I guess I would be willing to go to some lengths, and if that means eating gluten-free for life, so be it!

"I knew that attack on the thyroid was common in celiacs, because the celiac autoantigen tTG (it has a basic triplet) is also present in the thyroid and the celiac autoantibodies to tTG also cause an attack on the thyroid. But the autoantigen for Hashimoto’s Thyroiditis is thyroid peroxidase (TPO)."

http://coolinginflam...autoimmune.html

Thank you, I will show this to my doctor. And I will keep doing more research.

Does anyone else here feel like they are desperately trying to get better?

0

Share this post


Link to post
Share on other sites




"Does anyone else here feel like they are desperately trying to get better?"

Yes, please read as much as you can.

I have spent years learning the keys to my health. I do hope your answers are quicker, but know there have been MANY before you that havve struggled each day to obtain health and there will be many more that follow.

You are not alone - learn all you can.

1

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,113
    • Total Posts
      919,442
  • Topics

  • Posts

    • Hi Megan, Did the doctor test you for celiac disease?  You really shouldn't go gluten-free until all the testing for celiac disease is completed.  It is a little odd for a doctor to tell you to go gluten-free for no reason IMHO.  Did he/she explain the reason for it? Personally, I have learned over the years what I can eat safely and what I can't.  Occasionally I get hit but it is rare.  Simplifying your diet is a good first step.  Avoiding processed foods for a while and dairy also is good.  I suggest any change you make last for a month at least. Then try the food again. If you are eating 100 random ingredients/foods each day it is hard to figure these things out.  If you reduce it to a much smaller number of foods then things become simpler. Welcome to the forum!
    • hey! Wondering if I can get some good info/help from you guys! I just signed up for this website couple weeks ago. Whenever I would Google things this was always the first to pop up and I always found info on things I googled. I am pretty new to the gluten free thing. I had a hernia surgery back in Jan and after that I kept throwing up after eating, the DR. told me it was probably acid reflex caused from surgery but all the meds I tried nothing helped. I went back and was told to cut gluten out. I have been doing so since. When I first started I felt like I had it under control and didn't throw up for 3 weeks, now I find it happening more often. I do buy gluten-free things and read labels to the best I can. My frustration comes from not knowing what its from. How do you know if its from the day before or what you just ate? I hate not knowing. Especially when I haven't had gluten (or so I think) I have been keeping a journal but I just find it so hard. I get this feeling in my stomach and can feel it in my throat. Sometimes I puke once sometimes 5 times! Yesterday for lunch I made an omlet with chicken mushrooms and feta cheese. I threw up almost 20 min after. I have also tried the no dairy thing and it doesn't seem to make a difference so I don't think dairy is an issue as well.
    • I have been on a gluten-free diet for exactly one-year. During that time, I have had no stomach issues or problems when I inadvertently ingested gluten. The other day, I had GI discomfort (no vomiting or diarrhea) and my blood pressure spiked t0 200/98 (normally 119/75). As my GI discomfort subsided, my pressure crept back to normal. This took about 16-hours. I know that I ingested something with gluten, which I had thought was gluten-free.  It never bothered me before. Should I expect that the longer I'm gluten-free, the more susceptible I will be to having a pronounced reaction to inadvertent gluten exposure? Has anyone else had similar experiences with blood pressure spikes?
    • If this is helpful: My local public library had a copy of Breaking the Vicious Cycle by Elaine Gottschall.  There is a Facebook group, I believe it is easily found by searching SCD Diet, and it's a closed group.  If you go directly to the official website of Breaking the Vicious Cycle, there's lots of information for free available, including the basics about the intro diet and beyond.  I would go to the original source of this diet rather than go to other groups/books who have perhaps veered away from Elaine Gottschall's fundamentals. Best wishes to you!
    • AdrienJ, thank you so much! I dream of traveling more one day. I have spondylitis too. I'm so glad that a gluten free and casein free diet is helping you feel your best!
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,151
    • Most Online
      1,763

    Newest Member
    Ayryil
    Joined