Jump to content



   arrowShare this page:
   

   Get email alerts  Subscribe to FREE Celiac.com email alerts

 
Ads by Google:
Celiac.com Sponsor:                                    


Photo
- - - - -

Need Help With Tests Results Please


  • Please log in to reply
124 replies to this topic

#1 powerofpositivethinking

powerofpositivethinking

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 618 posts

Posted 21 January 2013 - 03:21 PM

I went to a GI last week, and he did order a celiac panel at my request but also wanted to try a sitz marker exam and liver/gallbladder ultrasound. I told him my main complaint was bloating and constipation...i won't list all the other symptoms right now. he was very nice, but he also said that people with celiac have D instead of C, which I know by now is just not true :( i will be getting the sitz and ultrasounds later this week, but the blood tests results came back today, and any input you can give would be much appreciated. I don't have a follow-up until almost the end of February.


Celiac Disease Comprehensive done by LabCorp

Deamidated Gliadin Abs, IgA 7 units which was negative
Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

Deamidated Gliadin Abs, IgG 43 units which was flagged as high
Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

t-Transglutaminase (tTG) IgA was < 2 which was in the negative range
Negative 0-3, Weak Positive 4-10, Positive >10

t-Transglutaminase (tTG) IgG was < 2 so it was also in the negative range
Negative 0-5, Weak Positive 6-9, Positive >9

Endomysial Antibody IgA Negative
Immunoglobulin A, Qn, Serum 243 mg/dL 91-414 is in their negative range of 91-414

so the only thing that wasn't negative was the IgG which was flagged as high

I've got my follow-up in a few weeks, but until then any insight is much appreciated! would my numbers be indicative of low IgA?

Thanks in advance!

Edited by powerofpositivethinking, 21 January 2013 - 08:27 PM.

  • 0

Diagnosed with celiac disease, fat malabsorption, severe pancreatic insufficiency (taking Creon) and vitamin K and D deficiency

Thankful for all the help I've received from members on this board!

Happy to have answers  :) 


Celiac.com Sponsor:

#2 frieze

frieze

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 1,073 posts

Posted 21 January 2013 - 10:51 PM

I went to a GI last week, and he did order a celiac panel at my request but also wanted to try a sitz marker exam and liver/gallbladder ultrasound. I told him my main complaint was bloating and constipation...i won't list all the other symptoms right now. he was very nice, but he also said that people with celiac have D instead of C, which I know by now is just not true :( i will be getting the sitz and ultrasounds later this week, but the blood tests results came back today, and any input you can give would be much appreciated. I don't have a follow-up until almost the end of February.


Celiac Disease Comprehensive done by LabCorp

Deamidated Gliadin Abs, IgA 7 units which was negative
Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

Deamidated Gliadin Abs, IgG 43 units which was flagged as high
Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

t-Transglutaminase (tTG) IgA was < 2 which was in the negative range
Negative 0-3, Weak Positive 4-10, Positive >10

t-Transglutaminase (tTG) IgG was < 2 so it was also in the negative range
Negative 0-5, Weak Positive 6-9, Positive >9

Endomysial Antibody IgA Negative
Immunoglobulin A, Qn, Serum 243 mg/dL 91-414 is in their negative range of 91-414

so the only thing that wasn't negative was the IgG which was flagged as high

I've got my follow-up in a few weeks, but until then any insight is much appreciated! would my numbers be indicative of low IgA?

Thanks in advance!

Maybe, they need to run an total IgA to know...
  • 0

#3 mushroom

mushroom

    Mushroom

  • Advanced Members
  • PipPipPipPipPipPip
  • 9,448 posts

Posted 22 January 2013 - 12:42 AM

Frieze is right; without running the total serum IgA there is no way of knowing if those are valid IgA results, especially when you consider that positive IgG score.
  • 0
Neroli


"Everything that can be counted does not necessarily count; everything that counts cannot necessarily be counted." - Albert Einstein

"Life is not weathering the storm; it is learning to dance in the rain"

"Whatever the question, the answer is always chocolate." Nigella Lawson

------------

Caffeine free 1973
Lactose free 1990
(Mis)diagnosed IBS, fibromyalgia '80's and '90's
Diagnosed psoriatic arthritis 2004
Self-diagnosed gluten intolerant, gluten-free Nov. 2007
Soy free March 2008
Nightshade free Feb 2009
Citric acid free June 2009
Potato starch free July 2009
(Totally) corn free Nov. 2009
Legume free March 2010
Now tolerant of lactose

Celiac.com - Celiac Disease Board Moderator

#4 powerofpositivethinking

powerofpositivethinking

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 618 posts

Posted 22 January 2013 - 07:51 AM

ok I've been trying to make sense of this total IgA with looking online, but I'm still confused.

Here's exactly how it is displayed on my report:

Endomysial Antibody IgA Negative Negative

Immunoglobulin A, Qn, Serum 243 mg/dL 91-414


is the immunoglobulin A test the same as testing for Total serum IgA?
  • 0

Diagnosed with celiac disease, fat malabsorption, severe pancreatic insufficiency (taking Creon) and vitamin K and D deficiency

Thankful for all the help I've received from members on this board!

Happy to have answers  :) 


#5 nvsmom

nvsmom

    Moderator

  • Moderators
  • PipPipPipPipPipPip
  • 3,068 posts

Posted 22 January 2013 - 09:26 AM

ok I've been trying to make sense of this total IgA with looking online, but I'm still confused.

Here's exactly how it is displayed on my report:

Endomysial Antibody IgA Negative Negative

Immunoglobulin A, Qn, Serum 243 mg/dL 91-414


is the immunoglobulin A test the same as testing for Total serum IgA?


I believe that is your total serum IgA, and it looks good to me.

I think you've tested positive... Bloating and constipation, along with stomach aches were my main symptoms ... I thought. A few other things resolved (like my migraines) after going gluten-free. If you start on the gluten-free diet, you might be pleasantly surprised by how your health improves.

Best wishes.
  • 0
Nicole Posted Image

"Acceptance is the key to happiness."

ITP - 1993
Celiac - June, 2012
Hypothyroid - August, 2012

CANADIAN

Celiac.com - Celiac Disease Board Moderator

#6 GottaSki

GottaSki

    "The past is the past...I've got places to be."

  • Advanced Members
  • PipPipPipPipPipPip
  • 4,839 posts

Posted 22 January 2013 - 10:29 AM

I agree with Nicole.

Your Total IgA is within normal range -- the positive DGP IgG is enough reason to remove ALL gluten (IMO). Is there anyway you can move the follow up - up? Is the follow up with Primary or GI?

If you are considering an endoscopy - try to get it done as soon as possible -- blood doesn't always show the whole picture.

Hang in there :)
  • 0

-Lisa

Undiagnosed Celiac Disease ~ 43 years

3/26/09 gluten-free - dignosed celiac - blood 3/3/09, biopsy 3/26/09, double DQ2 / single DQ8 positive

10/25/13 - MCAD

Health history since celiac diagnosis became too long -- moved to the "about me" section of my profile

My children and I all have multiple copies of the genes for Celiac Disease, along with large variety of symptoms/resolution gluten-free

Current tally from me, three kids and two grands: 4 diagnosed with Celiac Disease, 2 NCGS

Get PROPERLY tested BEFORE REMOVING GLUTEN.

ALWAYS independently research health related information found on internet forums/blogs.

"LTES" a Gem :)


#7 powerofpositivethinking

powerofpositivethinking

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 618 posts

Posted 22 January 2013 - 06:25 PM

thanks for all the feedback! Nicole and Mushroom, you both left me comments regarding my initial doctor's write-up which were extremely helpful!! I put things in bullets, and he did look over it, but when he asked what my biggest complaint was, I said bloating and constipation. At first, he wanted to prescribe a fiber supplement and enemas and send me on, but with that write-up and myself on the verge of tears after his suggestion, he agreed to the celiac panel that I requested, but in addition he also ordered a liver/gallbladder ultrasound and a sitz marker exam. Also, he wants me to work-up to 5 Citrucel, 3 times a day. I've had problems with other fiber supplements, but so far this one seems to be helping with some constipation, but I still feel bloated.

Lisa, unfortunately I don't think I can move the appointment because they told me to schedule my follow-up two weeks after completing the liver/gallbladder ultrasound and the sitz marker exam which puts me around 2/13, but the doctor is out of the office until 2/21, so that was my first available :( he said that if they didn't find anything from those other tests that a colonoscopy and endoscopy would be needed. my brother asked my GP about gluten at an appointment last week, in which he responded if you were intolerant, you would have a rash :angry: needless to say this is one of the few times I'm glad I pay more to have a PPO plan, so I didn't need approval from him to make the GI appointment.

based on what the GI said before that people with celiac have D instead of C, I need to gather some research from journals to persuade him to proceed with an endoscopy regardless of the sitz and ultrasound results since he's not quite in my camp haha if you've got any research or information from credible sources that says high DGP igG is reason enough to do an endoscopy regardless of the igA values, please send it my way. now it's time to start researching to build my case :D
  • 0

Diagnosed with celiac disease, fat malabsorption, severe pancreatic insufficiency (taking Creon) and vitamin K and D deficiency

Thankful for all the help I've received from members on this board!

Happy to have answers  :) 


#8 mushroom

mushroom

    Mushroom

  • Advanced Members
  • PipPipPipPipPipPip
  • 9,448 posts

Posted 22 January 2013 - 06:32 PM

Here's one to get you started:

http://www.nlm.nih.g...icle/000233.htm
  • 0
Neroli


"Everything that can be counted does not necessarily count; everything that counts cannot necessarily be counted." - Albert Einstein

"Life is not weathering the storm; it is learning to dance in the rain"

"Whatever the question, the answer is always chocolate." Nigella Lawson

------------

Caffeine free 1973
Lactose free 1990
(Mis)diagnosed IBS, fibromyalgia '80's and '90's
Diagnosed psoriatic arthritis 2004
Self-diagnosed gluten intolerant, gluten-free Nov. 2007
Soy free March 2008
Nightshade free Feb 2009
Citric acid free June 2009
Potato starch free July 2009
(Totally) corn free Nov. 2009
Legume free March 2010
Now tolerant of lactose

Celiac.com - Celiac Disease Board Moderator

#9 nvsmom

nvsmom

    Moderator

  • Moderators
  • PipPipPipPipPipPip
  • 3,068 posts

Posted 22 January 2013 - 09:29 PM

based on what the GI said before that people with celiac have D instead of C, I need to gather some research from journals to persuade him to proceed with an endoscopy regardless of the sitz and ultrasound results since he's not quite in my camp haha if you've got any research or information from credible sources that says high DGP igG is reason enough to do an endoscopy regardless of the igA values, please send it my way. now it's time to start researching to build my case :D

Shelley Case (Gluten-Free Diet) mentions the symptoms and tests here:
http://www.glutenfre...osed_Celiac.pdf

This article discusses "c" in the clinical presentations, as well as the various tests, but the author is largely pointing out that blood tests can make the endoscopy unnecessary.
http://ajcn.nutritio...t/69/3/354.full

This site discusses lab tests:
http://labtestsonlin.../celiac/start/2

Good luck!!
  • 0
Nicole Posted Image

"Acceptance is the key to happiness."

ITP - 1993
Celiac - June, 2012
Hypothyroid - August, 2012

CANADIAN

Celiac.com - Celiac Disease Board Moderator

#10 powerofpositivethinking

powerofpositivethinking

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 618 posts

Posted 25 January 2013 - 07:09 PM

these article links are definitely helpful and much appreciated! thanks :D
  • 0

Diagnosed with celiac disease, fat malabsorption, severe pancreatic insufficiency (taking Creon) and vitamin K and D deficiency

Thankful for all the help I've received from members on this board!

Happy to have answers  :) 


#11 powerofpositivethinking

powerofpositivethinking

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 618 posts

Posted 26 January 2013 - 04:13 AM

does anyone have any background info on the University of California San Diego Research Center for Celiac? www.celiaccenter.ucsd.edu the information on their site is going to be very helpful for me when I visit my GI, and they explain things in simple terms :)

helpful quotes: "Only a small portion of affected people manifest the typical symptoms of celiac disease."
and my personal favorite, "In adults screened for celiac disease, between 2.6 to 3.8% of patients with constipation, abdominal pain or diarrhea were found to have celiac disease, while only one third of patients with newly diagnosed celiac disease reported chronic diarrhea."

Edited by powerofpositivethinking, 26 January 2013 - 05:23 AM.

  • 0

Diagnosed with celiac disease, fat malabsorption, severe pancreatic insufficiency (taking Creon) and vitamin K and D deficiency

Thankful for all the help I've received from members on this board!

Happy to have answers  :) 


#12 Ann1231

Ann1231

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 160 posts

Posted 26 January 2013 - 01:39 PM

*sorry for the extra post. was posting from new phone, didn't realize it sent this one*
  • 0
hypothyroid
hypoglycemic (diagnosed 1997 but symptomatic since grade school)
fibromyalgia
rheumatoid arthritis (diagnosed January 2005)
peanut allergy

restarting gluten-free January 20, 2013

elevated liver enzymes + symptoms indicated celiac January 31, 2013. Dr. didn't want to run further tests due to other health complications

#13 Ann1231

Ann1231

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 160 posts

Posted 26 January 2013 - 01:42 PM

Thank you for this thread. I have the atypical symptoms and also have elevated liver enzymes. I have been thru ultrasound and it came back ok. I see dr again next Thursday and will ask about celiac
  • 0
hypothyroid
hypoglycemic (diagnosed 1997 but symptomatic since grade school)
fibromyalgia
rheumatoid arthritis (diagnosed January 2005)
peanut allergy

restarting gluten-free January 20, 2013

elevated liver enzymes + symptoms indicated celiac January 31, 2013. Dr. didn't want to run further tests due to other health complications

#14 GottaSki

GottaSki

    "The past is the past...I've got places to be."

  • Advanced Members
  • PipPipPipPipPipPip
  • 4,839 posts

Posted 26 January 2013 - 06:53 PM

does anyone have any background info on the University of California San Diego Research Center for Celiac? www.celiaccenter.ucsd.edu the information on their site is going to be very helpful for me when I visit my GI, and they explain things in simple terms :)

helpful quotes: "Only a small portion of affected people manifest the typical symptoms of celiac disease."
and my personal favorite, "In adults screened for celiac disease, between 2.6 to 3.8% of patients with constipation, abdominal pain or diarrhea were found to have celiac disease, while only one third of patients with newly diagnosed celiac disease reported chronic diarrhea."


I'm in San Diego -- Dr. Crowe is my Celiac Doctor -- along with Dr. Harmon at UCLA -- he was the former director at UCSD and was the doc that diagnosed me. Have you seen their youtube from a conference several years ago -- really helped me understand Celiac when first diagnosed.
  • 0

-Lisa

Undiagnosed Celiac Disease ~ 43 years

3/26/09 gluten-free - dignosed celiac - blood 3/3/09, biopsy 3/26/09, double DQ2 / single DQ8 positive

10/25/13 - MCAD

Health history since celiac diagnosis became too long -- moved to the "about me" section of my profile

My children and I all have multiple copies of the genes for Celiac Disease, along with large variety of symptoms/resolution gluten-free

Current tally from me, three kids and two grands: 4 diagnosed with Celiac Disease, 2 NCGS

Get PROPERLY tested BEFORE REMOVING GLUTEN.

ALWAYS independently research health related information found on internet forums/blogs.

"LTES" a Gem :)


#15 powerofpositivethinking

powerofpositivethinking

    Advanced Community Member

  • Advanced Members
  • PipPipPipPipPipPip
  • 618 posts

Posted 27 January 2013 - 05:21 AM

Lisa, great video!! i'm going to post the link in this thread I love how they explain things in easy to understand terms. very helpful!
  • 0

Diagnosed with celiac disease, fat malabsorption, severe pancreatic insufficiency (taking Creon) and vitamin K and D deficiency

Thankful for all the help I've received from members on this board!

Happy to have answers  :) 



0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users

Celiac.com Sponsors: