Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Need Help With Tests Results Please
3 3

131 posts in this topic

I went to a GI last week, and he did order a celiac panel at my request but also wanted to try a sitz marker exam and liver/gallbladder ultrasound. I told him my main complaint was bloating and constipation...i won't list all the other symptoms right now. he was very nice, but he also said that people with celiac have D instead of C, which I know by now is just not true :( i will be getting the sitz and ultrasounds later this week, but the blood tests results came back today, and any input you can give would be much appreciated. I don't have a follow-up until almost the end of February.

Celiac Disease Comprehensive done by LabCorp

Deamidated Gliadin Abs, IgA 7 units which was negative

Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

Deamidated Gliadin Abs, IgG 43 units which was flagged as high

Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

t-Transglutaminase (tTG) IgA was < 2 which was in the negative range

Negative 0-3, Weak Positive 4-10, Positive >10

t-Transglutaminase (tTG) IgG was < 2 so it was also in the negative range

Negative 0-5, Weak Positive 6-9, Positive >9

Endomysial Antibody IgA Negative

Immunoglobulin A, Qn, Serum 243 mg/dL 91-414 is in their negative range of 91-414

so the only thing that wasn't negative was the IgG which was flagged as high

I've got my follow-up in a few weeks, but until then any insight is much appreciated! would my numbers be indicative of low IgA?

Thanks in advance!

Edited by powerofpositivethinking
0

Share this post


Link to post
Share on other sites


Ads by Google:

I went to a GI last week, and he did order a celiac panel at my request but also wanted to try a sitz marker exam and liver/gallbladder ultrasound. I told him my main complaint was bloating and constipation...i won't list all the other symptoms right now. he was very nice, but he also said that people with celiac have D instead of C, which I know by now is just not true :( i will be getting the sitz and ultrasounds later this week, but the blood tests results came back today, and any input you can give would be much appreciated. I don't have a follow-up until almost the end of February.

Celiac Disease Comprehensive done by LabCorp

Deamidated Gliadin Abs, IgA 7 units which was negative

Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

Deamidated Gliadin Abs, IgG 43 units which was flagged as high

Negative 0-19, Weak Positive 20-30, Moderate to Strong Positive >30

t-Transglutaminase (tTG) IgA was < 2 which was in the negative range

Negative 0-3, Weak Positive 4-10, Positive >10

t-Transglutaminase (tTG) IgG was < 2 so it was also in the negative range

Negative 0-5, Weak Positive 6-9, Positive >9

Endomysial Antibody IgA Negative

Immunoglobulin A, Qn, Serum 243 mg/dL 91-414 is in their negative range of 91-414

so the only thing that wasn't negative was the IgG which was flagged as high

I've got my follow-up in a few weeks, but until then any insight is much appreciated! would my numbers be indicative of low IgA?

Thanks in advance!

Maybe, they need to run an total IgA to know...
0

Share this post


Link to post
Share on other sites

Frieze is right; without running the total serum IgA there is no way of knowing if those are valid IgA results, especially when you consider that positive IgG score.

0

Share this post


Link to post
Share on other sites

ok I've been trying to make sense of this total IgA with looking online, but I'm still confused.

Here's exactly how it is displayed on my report:

Endomysial Antibody IgA Negative Negative

Immunoglobulin A, Qn, Serum 243 mg/dL 91-414

is the immunoglobulin A test the same as testing for Total serum IgA?

0

Share this post


Link to post
Share on other sites

ok I've been trying to make sense of this total IgA with looking online, but I'm still confused.

Here's exactly how it is displayed on my report:

Endomysial Antibody IgA Negative Negative

Immunoglobulin A, Qn, Serum 243 mg/dL 91-414

is the immunoglobulin A test the same as testing for Total serum IgA?

I believe that is your total serum IgA, and it looks good to me.

I think you've tested positive... Bloating and constipation, along with stomach aches were my main symptoms ... I thought. A few other things resolved (like my migraines) after going gluten-free. If you start on the gluten-free diet, you might be pleasantly surprised by how your health improves.

Best wishes.

0

Share this post


Link to post
Share on other sites




I agree with Nicole.

Your Total IgA is within normal range -- the positive DGP IgG is enough reason to remove ALL gluten (IMO). Is there anyway you can move the follow up - up? Is the follow up with Primary or GI?

If you are considering an endoscopy - try to get it done as soon as possible -- blood doesn't always show the whole picture.

Hang in there :)

0

Share this post


Link to post
Share on other sites

thanks for all the feedback! Nicole and Mushroom, you both left me comments regarding my initial doctor's write-up which were extremely helpful!! I put things in bullets, and he did look over it, but when he asked what my biggest complaint was, I said bloating and constipation. At first, he wanted to prescribe a fiber supplement and enemas and send me on, but with that write-up and myself on the verge of tears after his suggestion, he agreed to the celiac panel that I requested, but in addition he also ordered a liver/gallbladder ultrasound and a sitz marker exam. Also, he wants me to work-up to 5 Citrucel, 3 times a day. I've had problems with other fiber supplements, but so far this one seems to be helping with some constipation, but I still feel bloated.

Lisa, unfortunately I don't think I can move the appointment because they told me to schedule my follow-up two weeks after completing the liver/gallbladder ultrasound and the sitz marker exam which puts me around 2/13, but the doctor is out of the office until 2/21, so that was my first available :( he said that if they didn't find anything from those other tests that a colonoscopy and endoscopy would be needed. my brother asked my GP about gluten at an appointment last week, in which he responded if you were intolerant, you would have a rash :angry: needless to say this is one of the few times I'm glad I pay more to have a PPO plan, so I didn't need approval from him to make the GI appointment.

based on what the GI said before that people with celiac have D instead of C, I need to gather some research from journals to persuade him to proceed with an endoscopy regardless of the sitz and ultrasound results since he's not quite in my camp haha if you've got any research or information from credible sources that says high DGP igG is reason enough to do an endoscopy regardless of the igA values, please send it my way. now it's time to start researching to build my case :D

0

Share this post


Link to post
Share on other sites

based on what the GI said before that people with celiac have D instead of C, I need to gather some research from journals to persuade him to proceed with an endoscopy regardless of the sitz and ultrasound results since he's not quite in my camp haha if you've got any research or information from credible sources that says high DGP igG is reason enough to do an endoscopy regardless of the igA values, please send it my way. now it's time to start researching to build my case :D

Shelley Case (Gluten-Free Diet) mentions the symptoms and tests here:

http://www.glutenfreediet.ca/img/Undiagnosed_Celiac.pdf

This article discusses "c" in the clinical presentations, as well as the various tests, but the author is largely pointing out that blood tests can make the endoscopy unnecessary.

http://ajcn.nutrition.org/content/69/3/354.full

This site discusses lab tests:

http://labtestsonline.org/understanding/conditions/celiac/start/2

Good luck!!

0

Share this post


Link to post
Share on other sites

these article links are definitely helpful and much appreciated! thanks :D

0

Share this post


Link to post
Share on other sites

does anyone have any background info on the University of California San Diego Research Center for Celiac? www.celiaccenter.ucsd.edu the information on their site is going to be very helpful for me when I visit my GI, and they explain things in simple terms :)

helpful quotes: "Only a small portion of affected people manifest the typical symptoms of celiac disease."

and my personal favorite, "In adults screened for celiac disease, between 2.6 to 3.8% of patients with constipation, abdominal pain or diarrhea were found to have celiac disease, while only one third of patients with newly diagnosed celiac disease reported chronic diarrhea."

Edited by powerofpositivethinking
0

Share this post


Link to post
Share on other sites

*sorry for the extra post. was posting from new phone, didn't realize it sent this one*

0

Share this post


Link to post
Share on other sites

Thank you for this thread. I have the atypical symptoms and also have elevated liver enzymes. I have been thru ultrasound and it came back ok. I see dr again next Thursday and will ask about celiac

0

Share this post


Link to post
Share on other sites

does anyone have any background info on the University of California San Diego Research Center for Celiac? www.celiaccenter.ucsd.edu the information on their site is going to be very helpful for me when I visit my GI, and they explain things in simple terms :)

helpful quotes: "Only a small portion of affected people manifest the typical symptoms of celiac disease."

and my personal favorite, "In adults screened for celiac disease, between 2.6 to 3.8% of patients with constipation, abdominal pain or diarrhea were found to have celiac disease, while only one third of patients with newly diagnosed celiac disease reported chronic diarrhea."

I'm in San Diego -- Dr. Crowe is my Celiac Doctor -- along with Dr. Harmon at UCLA -- he was the former director at UCSD and was the doc that diagnosed me. Have you seen their youtube from a conference several years ago -- really helped me understand Celiac when first diagnosed.

0

Share this post


Link to post
Share on other sites

Lisa, great video!! i'm going to post the link in this thread http://www.youtube.com/watch?v=QR2LvQmoF1Y I love how they explain things in easy to understand terms. very helpful!

Yes, this video was very helpful to me -- Dr. Harmon gave me a DVD of it when diagnosed -- then I found on youtube when I wanted to show others on the forum.

Note for anyone reading along -- the video is over an hour long -- Drs K and H are worth listening to...the dietician -- not so much ;)

0

Share this post


Link to post
Share on other sites

i've also been browsing this report from the World Gastroenterology Organisation. IMO, my GI doc should see this report as a very credible source since it's published by his peers! http://www.worldgastroenterology.org/assets/export/userfiles/2012_Celiac%20Disease_long_FINAL.pdf

at the top of p. 7 it discusses Nonclassic symptoms, which have bloating and constipation listed, so I will definitely be highlighting that

on the top of p. 8 it has a great diagram I will be sharing with my doctor at the follow-up which says that since I tested high for DGP igG he should perform a small bowel biopsy

more info to add to my file :)

0

Share this post


Link to post
Share on other sites

so i've completed all my tests for my follow-up GI apt on February 21st, and so far I don't know the results of my gallbladder/liver ultrasound, but I've gotten outcomes on the other two. I've posted already, but for the full celiac panel, I scored high on the DGP igG test only, and I ate gluten at almost every meal in the week leading up to it, but I was eating gluten light before that week, so I bet my score would have been higher. I've been consuming a lot of gluten for my follow-up. I was supposed to be x-rayed three times for my sitz marker exam, but on the second x-ray/4th day, the radiologist said everything had come out so I wouldn't have to come back for the third x-ray :)

so i may be passing things in a timely fashion according to the medical world, but i've decided I'm continuously bloated, and as I saw in another thread, "always feel a little bit pregnant." this feeling used to only happen before my time of the month, but now it sticks with me constantly :mellow:

0

Share this post


Link to post
Share on other sites

so i've completed all my tests for my follow-up GI apt on February 21st, and so far I don't know the results of my gallbladder/liver ultrasound, but I've gotten outcomes on the other two. I've posted already, but for the full celiac panel, I scored high on the DGP igG test only, and I ate gluten at almost every meal in the week leading up to it, but I was eating gluten light before that week, so I bet my score would have been higher. I've been consuming a lot of gluten for my follow-up. I was supposed to be x-rayed three times for my sitz marker exam, but on the second x-ray/4th day, the radiologist said everything had come out so I wouldn't have to come back for the third x-ray :)

so i may be passing things in a timely fashion according to the medical world, but i've decided I'm continuously bloated, and as I saw in another thread, "always feel a little bit pregnant." this feeling used to only happen before my time of the month, but now it sticks with me constantly :mellow:

Congratulations on passing the sitz marker exam ;)

I failed miserably -- trust me -- you don't want to get to the stage that nearly all markers were present and accounted for at day five -- xray tech did a double take, asked me if I had waited the full five days and said she never saw that many markers remain.

In my case, the severe bloat was not just my abdomen -- it was more prominent there - I looked between 6-9 months preg each evening the year or two before I was finally dx'd -- but now that my inflammation is finally leaving my body it is obvious that every part of my body had inflammation -- although I failed every blood test for inflammation over the past 30 years.

I'm curious -- What was your Total Serum IgA?

Any nutritional defieciences - have they all been checked -- Vit Bs, D, K, Iron, Ferritin, Copper and Zinc -- Along with a CMP (Complete Metaboloic Panel)?

0

Share this post


Link to post
Share on other sites

Congratulations on passing the sitz marker exam ;)

I failed miserably -- trust me -- you don't want to get to the stage that nearly all markers were present and accounted for at day five -- xray tech did a double take, asked me if I had waited the full five days and said she never saw that many markers remain.

In my case, the severe bloat was not just my abdomen -- it was more prominent there - I looked between 6-9 months preg each evening the year or two before I was finally dx'd -- but now that my inflammation is finally leaving my body it is obvious that every part of my body had inflammation -- although I failed every blood test for inflammation over the past 30 years.

I'm curious -- What was your Total Serum IgA?

Any nutritional defieciences - have they all been checked -- Vit Bs, D, K, Iron, Ferritin, Copper and Zinc -- Along with a CMP (Complete Metaboloic Panel)?

Lisa, I'm glad you were diagnosed and are on your way to recovery!! The abdominal bloating frustrates me the most. I do ab exercises, but when you can never pull your stomach in the whole way, it gets frustrating because it never feels like I am doing it the best I can :P I can also tell when my face bloats because my eyelids get droopy, and I get a lot of water retention above my knees.

My Immunoglobulin A, Qn, Serum was 243 mg/dL which was in their normal range of 91-414. In my first post I have it incorrectly labeled since I realized the negative was referring to the EMA result. I haven't had any nutritional testing done. The only thing I know is my hemoglobin level was 13.0 last year, which meant I was alright to give blood, but that was last March. It was the first time I gave blood and almost fainted. It was not a plesant expierence...

I haven't come across anything about a Complete Metabolic Panel. What does that consist of?

0

Share this post


Link to post
Share on other sites

Lisa, I'm glad you were diagnosed and are on your way to recovery!! The abdominal bloating frustrates me the most. I do ab exercises, but when you can never pull your stomach in the whole way, it gets frustrating because it never feels like I am doing it the best I can :P I can also tell when my face bloats because my eyelids get droopy, and I get a lot of water retention above my knees.

My Immunoglobulin A, Qn, Serum was 243 mg/dL which was in their normal range of 91-414. In my first post I have it incorrectly labeled since I realized the negative was referring to the EMA result. I haven't had any nutritional testing done. The only thing I know is my hemoglobin level was 13.0 last year, which meant I was alright to give blood, but that was last March. It was the first time I gave blood and almost fainted. It was not a plesant expierence...

I haven't come across anything about a Complete Metabolic Panel. What does that consist of?

CMP is a simple blood test -- usually one of the first docs run for any health concern. If you have not had a recent CBC, CMP or nutrient testing -- I highly recommend doing so ASAP. These will give a good snapshot of where you stand with regard to absorbing nutrients -- celiac disease prevents proper absorbtion.

0

Share this post


Link to post
Share on other sites

CMP is a simple blood test -- usually one of the first docs run for any health concern. If you have not had a recent CBC, CMP or nutrient testing -- I highly recommend doing so ASAP. These will give a good snapshot of where you stand with regard to absorbing nutrients -- celiac disease prevents proper absorbtion.

I will certainly ask for one at my follow-up. Thanks!

0

Share this post


Link to post
Share on other sites

CMP is a simple blood test -- usually one of the first docs run for any health concern. If you have not had a recent CBC, CMP or nutrient testing -- I highly recommend doing so ASAP. These will give a good snapshot of where you stand with regard to absorbing nutrients -- celiac disease prevents proper .

i have my lovely ob/gyn appointment :lol: this week and thought I would ask that doctor if she would be willing to order the CMP for me. I have to use LabCorp for my insurance, and this is what their CMP covers: Alanine aminotransferase (ALT/SGPT); albumin:globulin (A:G) ratio; albumin, serum; alkaline phosphatase, serum; aspartate aminotransferase (AST/SGOT); bilirubin, total; BUN; BUN:creatinine ratio; calcium, serum; carbon dioxide, total; chloride, serum; creatinine, serum; globulin, total; glucose, serum; potassium, serum; protein, total, serum; sodium, serum

Based on other posts, I also wanted to request Vitamin A, B, D, E, K, iron/ferritin, magnesium, zinc, thyroid with TSH, T3 and T4.

Anything else I should ask for??

Mine as well ask for everything, and see what I get :)

0

Share this post


Link to post
Share on other sites

Good List -- Make sure you request Free T3 and Free T4 -- that "free" is important.

CBC - Complete Blood Count

For Vitamin B -- I suggest you request B1,B2, B6 and B12.

I think you have had all your celiac antibodies -- just double check:

Total Serum IgA

tTG - BOTH IgA and IgG

DGP - BOTH IgA and IgG

EMA

AGA - if you have both DGP's that is usually enough, but if you haven't had AGA - BOTH IgA and IgG - it can't hurt.

Oh - Inflammation markers CRP, SED and RF

Good Luck!

PS...I forgot to add Copper to the list ;)

0

Share this post


Link to post
Share on other sites

Good List -- Make sure you request Free T3 and Free T4 -- that "free" is important.

CBC - Complete Blood Count

For Vitamin B -- I suggest you request B1,B2, B6 and B12.

I think you have had all your celiac antibodies -- just double check:

Total Serum IgA

tTG - BOTH IgA and IgG

DGP - BOTH IgA and IgG

EMA

AGA - if you have both DGP's that is usually enough, but if you haven't had AGA - BOTH IgA and IgG - it can't hurt.

Oh - Inflammation markers CRP, SED and RF

Good Luck!

PS...I forgot to add Copper to the list ;)

Lisa, thanks for the info! I had my ob/gyn apt today and asked the doctor to order the following:

Complete Metabolic Profile

Complete Blood Count

Vitamins A, B (B1, B2, B6, B12), D, E, K

Ferritin/iron

Magnesium

Folate

Potassium

Calcium

Zinc

Copper (I couldn't get this one, because they didn't have the proper storage equipment required to send it off to the lab, but I thought if they were able to do all the rest, it wasn't so bad :) )

Thyroid (TSH, Free T3 and Free T4)

Inflammation Markers CRP, SED and RF

I was happy that the doctor had no problem ordering all of these for me, and I will report back with the results when I find out!

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
3 3

  • Forum Statistics

    • Total Topics
      104,642
    • Total Posts
      921,566
  • Topics

  • Posts

    • Hello I'm happy to join, any help is greatly appreciated as it can be difficult by times for sure. Unfortunately, I have been told my doctor has definitely not been doing anything correctly and very backwards about Alot of things. I live in canada, and there are celiac support groups I have found but I am about 2 hours away from any. I live in a pretty rural area. Although,  I have still received some help from them , they prefer a diagnosis before helping out to much. My doctor has me on a waiting list to see a gastrointestinal specialist but whenever I called her office to inquire about an appointment time I was told there was a very long wait and that I was considered to be a non emergency. So I am waiting to get an appointment. I have seen a dermatoligist for some of my rashes and she said it was dermatitis and gave me different creams for them.  It is frustrating because I don't know how to go about getting a actual diagnosis besides this biopsy. I was told to request a different specialist, but supposedly there is a waiting period for most in our area. 
    • Thanks for all of the replies. I've just found out I'm not getting to see a dietician because of not having a definite diagnosis which is another blow. I've had loads of bloods done but they just say they're all normal. I did have low vitamin D and high parathyroid but it's sorted itself out after a course of high dose vitamin D and they're not checking it again for a year. No chance of getting referred to endocrinology, gastro won't do it and neither will my gp. I've tried giving up coffee and all fizzy juice and it hasn't made a difference. I'm exhausted and scared and still have no clue what to do next. My gp has zero experience dealing with this type of thing - last time I was there she said it could be because I've restricted my diet too much and I should eat more gluten-free replacement products - everything I've read online says this is the worst thing to do! I'm asking for a copy of the last blood results this week so I can go through them myself but other than that I'm pretty stuck. 
    • I really am iffy on talking about this side of my gluten issues, I think I am about to ruin my reputation on this forum coming about as some extreme crazy guy saying this but I wanted to get this off my chest and perhaps see if anyone else might share a similar trauma. I get emotional recalling it, this side of my reactions, as it is most ingrained and very traumatizing experience, and I am not proud of it as the mentality I have now disgust me but I am going to come out about it. One of the scariest things in this world is when your own mind turns against you, when you can not think about what you want to think about, when you can not do what you know you should be able to do. When I got glutened really bad these where things I felt with my own mind would start looping, and thoughts would not come together. I would loose comprehension, feel like I know I should be able to think about something but my mind was not working. The same thing looped over and over and over like a broken record, This led to anger, anxiety, depression, panic, top it off with loss of feeling in my hands and feet, and the pains in the gut......it was a nightmare. I would go as far as beating my head against walls and punching them out of frustration as to why my own body and mind where not working, I just wanted it to end the pain to stop. I still have scars on my fist from punching into a nail in a stud once and kept going.....I scared everyone and myself distanced my self from loved ones. And started running a bucket list accepting that I was going to die soon. Hell to this day parts of the brain damage seem to be permanent as I can no longer do computer programing or some forms of math, they just no longer make any sense or connect. Then we learned what was causing it, and once the symptoms started to fade, I would get very angry if someone in the shared house did something stupid and got me sick again. The fear of going back to that caused violent and drastic actions to get away from what was making me sick. The sheer fear of my own mind turning on me led me to drastic actions to prevent it, throwing everything away I thought could make me sick, making sure no one else used that kitchen, used freezer paper and gloves when fixing my foods and working in there. I really destroyed and burned all bridges I had then and alienated myself from others. In the end it motivated me to learn how to cook, to get and renovate my own apartment in a building downtown, and start a business to pay for my new diet, by selling safe food to others with this issues locally at farmer markets. But it changed me on a very deep level, that traumatic experience to this day I have a issue looking at others and dealing with other humans who eat that stuff.......the stuff that breaks my mind and body so horrifically. If I have to compare it to something its like watching aliens drinking antifreeze and eating poison.....it causes a subconscious level of disgust and slight envy. I really can not even look at the stuff without recall what it does and feeling a twitch. I know I am the alien here, but it feels vise versa, and I look down on the normal people as odd creatures.  I go to the store and find myself overly avoiding contamination, keeping stuff in my own bags, asking the cashier to scan and bag it as I pass it not letting it touch that flour I see on the belt. I am hyper sensitive to the stuff I know and that fear semi dominates my mind as crazy as it sounds.  I am recovering and am forcing myself to try to mingle with other humans overlooking that one thing, but that deep rooted trauma still flares up as a protective measure especially around foods.  I could talk on and on about the other side effects but this one is the hardest to talk about it, and I feel others might be able to relate to it.    
    • Time.  You need time to heal.  Yeah, I am like a broken record!  😄 So...Lycra is your best friend for now (that and old baggy sweats!).  Hang in there!  Hugs!     
    • So far dairy seems to be OK, as are eggs. I like canned chickpeas so will carry on with those. Beans I had ruled out at one point with the doctor's recommendation to go with the low FODMAPs diet but will reintroduce those now I know it probably wasn't that causing the problems.
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,647
    • Most Online
      3,093

    Newest Member
    iFitCeliac
    Joined