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Weak Positive Ttg...

chickpea77

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chickpea77 Rookie
chickpea77
Posted

tTG 25 HI (20 - 30 units: weak positive)

GLIADIN AS IgA: 4 (<20 negative)

GLIADIN AB IgG: 11 (<20 negative

I am aware that there are reasons other than Celiac Disease for a positive tTG, I guess I'm just wondering if anyone has a child that was conclusively diagnosed when the only positive in the blood work was a weak positive tTG?

Sorry about the boring thread..... stresses out mum here *blush*

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Jamie1450 Apprentice
Jamie1450
Posted

My 2 year old (1 1/2 at the time) had tTG level 5 and anything over 4 was positive. His doctor diagnosed him with Celiac after seeing his large amounts of weight gain & reaction to gluten since going on a gluten free diet.

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mushroom Proficient
mushroom
Posted

chickpea, is your doctor planning to do any follow-up on this result? Like at least run the EMA and DGP. Or do an endoscopy with biopsy? In my book, any weak positive should not be dismissed out of hand. Oh, and did he run a total serum IgA?

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chickpea77 Rookie
chickpea77
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Posted

yes, we've done repeat bloodwork, just waiting on the results (ttg iga, dgp iga and igg, ema, total iga). we are book in to see a pediatric gi for feb.19..... getting very nervous about receiving a negative biopsy result (that is if the gi even orders the scope).

i do have a question though, would the ttg iga be weak positive if he was iga deficient? and would his iga be 4? this is all so confusing.... the family dr seems to think it is celiac, even with the low results, since he lost 4 pounds in the two weeks we packed in as much gluten as possible... i feel like a crazy mother, obsessed over getting a definitive answer but knowing i probably won't :(

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mushroom Proficient
mushroom
Posted

If his IgA were low and the tTG were weak positive it would be amazing, but that is one reason why it is checked. The weight loss is a telltale of celiac. You are not crazy at all -- you are doing what is right for your son. :)

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GottaSki Mentor
GottaSki
Posted

If his IgA were low and the tTG were weak positive it would be amazing, but that is one reason why it is checked. The weight loss is a telltale of celiac. You are not crazy at all -- you are doing what is right for your son. :)

Ditto.

Weak positive should not be dismissed. My entire family -- me, kids, grands all have weak positive or negative -- yet are clearly Celiac based on endos from me, daughter and grandson.

Symptoms plus weak positive is very telling.

Hang in there :)

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chickpea77 Rookie
chickpea77
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Posted

Thanks for your words of support.... did i mention that i love it here?!

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