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Autoimmune Disease Comorbidities

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I am brand new to the forum and have been learning a lot about Celiac and gluten (from this forum and other places as well).

My question is: do most with Celiac disease have other autoimmune diseases as well? I experienced Toxic exposure while in the military and have a bunch autoimmune diseases that my family (even my twin brother) do not have:

- MS

- Fibromyalgia

- Allergies & Asthma

- Hashimoto's Thyroiditis (Autoimmune Hypothyroidism - had to have a complete thyroidectomy)

- Endometriosis (had a complete hysterectomy)

I have a ton of GI symptoms and have had them for the past 10-15 years. They seem to have gotten worse over the years. I don't deal with weight loss and am over the top of my weight range: 5'9" & 190 lbs. I was experimenting with Gluten Free foods but have added various Gluten (I had pizza yesterday and a leftover slice this evening). Both times have left me bloated, gassy, growly stomach and sometimes diarrhea. MS can effect bowels too (I have a completely neurogenic bladder). I am due for a colonoscopy and am going to have them do an endoscopy while they are at it.

It seems my autoimmune system is going after something and seems to turn on itself. Wondering if there are a lot of folks here with dual autoimmune diseases. I'm pretty sick of the GI stuff and would like to get to the bottom of it.




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Yes absolutely celiac runs with autoimmune diseases, but the fact is that once you have one autoimmune disease you are at risk for many others. Celiac in particular has a strong association with hashimotos and type 1 diabetes, I believe possibly lupus as well.


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Yes absolutely celiac runs with autoimmune diseases, but the fact is that once you have one autoimmune disease you are at risk for many others. Celiac in particular has a strong association with hashimotos and type 1 diabetes, I believe possibly lupus as well.

Yep. I have hypothyroidism, type 2 diabetes, diverticular disease (new dx), kidney failure (early, I hope) and allergies/asthma ( adult onset only). Stinks doesn't it? I think I posted elsewhere it is like our own immune systems are attacking one organ after another....:(. I already did heart and lung disease some years ago. Hope some things soon resolve for you to some extent, GKYgirl....


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It seems to be especially common amoungst those of us celiacs who lived undiagnosed, and therefore untreated, for many years (this is just a personal observation though). I know that the inflammation from gluten can exasperate other autoimmune disorders, I'm not sure if or how it actually triggers them to start.

As far as I can tell, I've had celiac my entire life. I developed Hashimoto's and ITP as a young adult. I think I might have a connective tissue problem (like Lupus) too.

I wanted to add, if you are getting tested for celiac (through endoscopy, blood work or both) you should continue to eat gluten until your tests are complete, otherwise you could end up with a false negative test.


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    • They didn't. The labs were run two and a half weeks ago and before I got confirmation on here that it should be done despite my drs saying otherwise. I was glutened the week prior anyway so it would've been high regardless.  It's all very frustrating. So I guess I'll wait five or six months and go back and demand it vs asking about it. 
    • Did they run a DGP IGA?  While your DGP can take over a year to come down, I still think you should be getting tested every six months until you see a downward trend.  I am not making that up.  Google it.   My DGP was off the charts when I was glutened last summer.  My symtoms were severe, yet at diagnosis, I just had anemia.  It took six months for all symptoms to completely resolve (rashes and hives took the longest and three month to regain dairy).  What I am saying is that symptoms for celiac disease can change.    
    • Long pause because I wanted my latest lab results and they took forever.  Cortisol, ACTH, estadiol, vitamin a and whatever else were all fine. They are retesting my thyroid in four weeks. I definitely bought the wrong product and glutened myself a few weeks back so I guess that has to wait which really irritates me. My gliadin iga ab was greater than 100 almost two yrs ago at diagnosis so I guess sometime next yr I'll redo that and hope it's down :-/. Trying to do all the right things and get bad information from doctors.  Thanks for all the info you've shared and helped me with. I've had lab work every month since May and will next month for the thyroid again. Sigh. 
    • Hi Carle, Congrats on your symptoms going away.  I did seem to have reactions to rice for a while after going gluten-free.  But after some years on the gluten-free diet I can eat it again.  So reactions can change over time. I was searching for an article on gluten in common store products, but didn't find it.  There was a group that did testing on some common grocery products like beans, rice, corn etc that we would normally consider to be gluten-free naturally.  But they found some level of gluten in some of them.  So it's not impossible to pick up something off the shelf that ought to be naturally gluten-free and find it is contaminated.  That may have happened with the rice you ate.  A quick rinse of water before using the rice might help.
    • Hi Doit, The reference ranges to the right of the test result show the values the result ought to be in for normal readings (no celiac disease).  Your results appear to show no higher than normal results that I can see. However, you aren't following the recommended process for celiac disease blood testing.  The blood test is supposed to preceded by 12 weeks of daily gluten eating.  That is generally enough time to cause a sufficient quantity of antibodies to build up in the blood stream to be detectable by the tests. Not having antibodies in the blood stream doesn't mean you aren't being damaged.  People with DH (dermatitis herpetiformis) sometimes test negative on the standard blood tests.  My theory is possibly because the antibodies are concentrated in the skin instead of the blood.  In gut damage, it is possible the antibodies are concentrated in the gut, instead of the blood.  After some time they show up in the blood also.  The thinking is the antibodies go where the work is.  Anyway, theories aside, it takes very little gluten to kick off an immune response.  Those antibodies are not aimless soldiers.  They start doing their work and destroying gluten and gut tissue even if you don't feel symptoms.  Did you know there are some people who have no GI symptoms of celiac disease but still have it?  They call that silent celiac.  So going by symptoms is not a good way to judge actual damage in the gut. You are wise to go in for followup testing, but the followup testing is hopefully to show compliance with the gluten-free diet, and lower antibody test results.  Have your close family members been tested for celiac disease?  It sounds like they should be.   There is a 5% higher chance of them having celiac than the general population. Welcome to the forum!
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