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bobbyj

Member Since 22 Dec 2008
Offline Last Active Apr 27 2009 04:38 PM
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Posts I've Made

In Topic: New To Forum - B12 Deficiency And Gluten Intolerance?

22 April 2009 - 03:26 AM

Hello all. It's been a while, but I have now had some blood tests done and am looking for some help to interpret the results:

Anti-endomysial IgA - negative
Gliadin Peptides IgA - 2 RU/ml (normal range: 0-25 RU/ml)
Gliadin Peptides IgG - 109 (normal range: 0-25 RU/ml)

I was also tested for Intrinsic Factor antibodies and Parietal Cell antibodies (to test for pernicious anaemia, a cause of B12 deficiency) but was negative for both.

My doctor told me that, based on the tests, I can rule out celiac disease. He couldn't offer any explanation for why my Gliadin Peptides IgG result was so high - more than four times the upper normal range.

I don't know how normal or otherwise it is to have a very elevated Gliadin IgG result with a normal Gliadin IgA result, but I'd welcome any information on what this may mean?

Thanks.

In Topic: New To Forum - B12 Deficiency And Gluten Intolerance?

23 December 2008 - 08:02 PM

Have you ever had your TSH checked? Autoimmune hypothyroidism is much more common in celiacs than the general population... that could be another cause of your fatigue.


Yes, I've had my TSH and Free T3 and Free T4 checked. They were all within range, according to my doctor.

In Topic: New To Forum - B12 Deficiency And Gluten Intolerance?

22 December 2008 - 11:39 PM

Thanks to all for your replies.

I've been taking B12 injections and also sub-lingual lozenges. Strangly, my symptoms - primarily fatigue - have not improved much, though.

I don't know if I have pernicious anemia - the relevants tests (Intrinsic Factor antibody, Schilling test, etc) are not available where I live.

Similarly, I can't do the celiac disease antibody tests here.

I'm curious about people with confirmed celiac disease who have had an endoscopy or colonscopy. Are their results generally similar to mine (in terms of slightly flattened villi) or are there also other indicators of celiac disease in their biopsy results? According to another doctor I saw today, a biopsy should conclusively reveal whether or not there is celiac disease.

The doctor who did the colonscopy did not tell me that the B12 deficiency was caused by the flattened mucosa. She basically said that intestinal malabsorption could be ruled out as a cause of my deficiency, because I did not have symptoms such as chronic diarrhea and I did not have other deficiencies, particularly iron deficiency. She gave the same reasons for why she didn't think I had celiac disease (when I raised the issue, not her). She said that in even mild cases of celiac disease there would be an iron deficiency.

As I am not convinced of my doctor's knowledge on this subject, I'd appreciate any further thoughts from forum members. In addition, any suggestions of knowledgeable doctors (anywhere in the world) who I might try to consult with by email to get a second opinion on my test results would be much appreciated.

Thanks.