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stri8ed

Member Since 16 Jun 2011
Offline Last Active Sep 24 2014 11:57 AM
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Posts I've Made

In Topic: Desensitizing The "other Food Intolerances"

07 April 2014 - 07:56 PM

I decided to eat most of those foods only once every 8 days.  I've actually developed new delayed food allergies to some foods that I was eating once every 4 days.  That happened with allergenic foods - seeds and nuts mostly. 

 

I had the same issue. I was doing a 4 day rotation diet to avoid developing further sensitivities, and In spite of this, I had developed new sensitivities (primarily to high protein foods). I found what worked for me, is limiting the protein content to 15 - 20 grams, of a given food, on a 4 day rotation. This makes sense when you consider the theory behind "leaky gut". As we know, allergies are developed against proteins, so naturally, the more protein antigens that pass through a hyper-permeable GI tract, the more likely an immune response will develop. It seems there is a certain threshold of antigens which the immune system will tolerate before sensitization occurs. So the idea behind a rotation diet, would be to keep the antigen concentrations for a given food below that threshold. Here is an image I copied out of an immunology book, which seems to relate nicely:

 

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Also, Its been shown that following an allergic reaction in the GI tract, the intestines become more permeable (leaky). I can say for certain in my experience, I am more prone to developing further sensitivities soon after I have a big reaction (by eating a big portion of a food I am sensitive to). So that's something to keep in mind.


In Topic: Desensitizing The "other Food Intolerances"

07 April 2014 - 07:30 PM

More and more, I am becoming convinced that these "food sensitivities" are indeed a local IGE sensitization in the GI tract. Consider the case of the nasal mucosa: Its estimated that over 40% of people thought to have "nonallergic rhinitis", actually have local allergic rhinitis (IGE mediated). Why should we assume the GI mucosa is that different? Its already been proven that IGE can be produced locally in the GI tract, so its more a question of just how prevalent it is. Now considering the vast array of "non-allergic" (yet food/antigen-triggered) inflammatory conditions of the GI tract, I would suspect the rate to be at least 40% if not higher.

 

I have brought this up with a few doctors (one of them a leading gastroenterologist), and they are all in agreement that local allergy of the GI is a real thing. The problem is, unlike rhinitis where you can easily and objectively test for allergic sensitization, there is no easy way of doing so in the GI tract. Additionally, with all the quackery surrounding the topic of "food sensitivities/intolerance", doctors & researchers are less keen on touching this stuff.


In Topic: 4 Year Old Bloating

03 February 2014 - 03:29 PM

If you suspect it may be a food sensitivity, there is a very simple way to find out. Try an elimination diet for a few weeks, and see how your son responds. If the symptoms subside, then its clearly a food triggering them.


In Topic: Do Any Usa Doctors Prescribe Oral Ketotifen?

26 January 2014 - 06:24 PM

He guys, if any of you are still going down the mast cell stabiliser path?. I've been on the Pemirolast potassium for about 3 weeks now, from the very little information I could find about it, it seems to be the either the best mast cell stabiliser going or at least equally good to cromolyn . As far as I can tell it works like a boss. Zero side effects that I'm able to feel/tell. And I haven't had any discomfort in the gut at all while not been especailly careful with my food. Not sure what's going to happen long term as I'm using it for other problems aside from a dodgy gut. We will see. I plan to take it for several months and if my blood work is improving I'll take it for a year and see what happens. I had a blood test one week into the Pemirolast and it was the best result I've had in a few years but lets not count the chickens just yet. As far as food problems go, this seems good stuff.

 

I forgot something, I'm currently the heaviest I've ever been in my life (66kg clothed), this time last year I was 55kg. Very happy about that.

 

I have never heard of that before. Where did you purchase it from? Thus far, Ketotifen has failed me, and cromolyn is a bit of mixed bag. It does seem to partially relieve all my symptoms (which indicates my reactions stem from the GI tract), however I seem to react to it slightly, which gives me additional symptoms, and probably inhibits its full absorption and effectiveness. I am very interested in FAHF-2. The more I read about it, the more promising it seems. I may consider seeing Dr Li in her private practice in NY, and trying to get her to provide me with the formula, as it it may well take years until its on the market.

 

As I mentioned earlier, even after eliminating all my dozens of sensitivities/allergens from my diet, I still experience symptoms after eating. Hence, I really need something to work, simply so I can function properly on a day to day basis.


In Topic: Do Any Usa Doctors Prescribe Oral Ketotifen?

28 December 2013 - 08:07 AM

Yes, there are. My doctor (in Chicago) prescribed it for me, though I had to explicitly ask him to, as he was not very familiar with it. Given that Ketotifen has a proven efficacy in the treatment of food allergies, I see no reason why a doctor would not be willing prescribe it.

 

Unfortunately for me, I did not tolerate Ketotifen well, so I dropped it after a few weeks. I still have tons left over. Right now im experimenting with different doses of Cromolyn, to try and get a working situation.

 

I seem to have a similar situation like yourself, where I have dozens of food allergies (almost immediate onset), which don't show up in prick-tests. I have been able to prevent new allergies by following a low-protein rotation diet, however I have become so sensitive to even traces of any of my existing allergens, that I pretty much have reactions (albeit milder) after eating any meals. I have an appointment soon with an expert immunologist, and I am hoping he can bring some new ideas to the table.

 

Something I have been reading up on recently is xolair (Omalizumab). Its essentially an injectable antibody that binds to the IGE antibodies in human serum, thus preventing those antibodies from binding to mast cells, which in turn leads to diminished allergic reactions. It has some pretty impressive results in clinical studies, though it has most been mostly used for asthmatics. Interestingly, it has been proven to be effective in cases where the immune problems where not IGE mediated. The downside is, the treatment is crazy expensive, and relatively new, and not much studies have been done with food allergies.