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Member Since 05 Feb 2013
Offline Last Active Private

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In Topic: Newbie- Seeing Gi About Celiac Disease

05 February 2013 - 06:51 PM

This is the test (all of them) for Celiac Disease:

Anti-Gliadin (AGA) IgA
Anti-Gliadin (AGA) IgG
Anti-Endomysial (EMA) IgA
Anti-Tissue Transglutaminase (tTG) IgA
Deamidated Gliadin Peptide (DGP) IgA and IgG
Total Serum IgA

Thank you!! I will make sure to take this list with me to the appointment.

Your post made me think of a couple of things that might help you. Regarding family history, have your grandparents, aunts, uncles, cousins been diganosed with other autoimmune diseases? (Cancer, diabetes, M.S., Leukemia...or irritable bowel syndrome... there are more than 200 symptoms and sometimes family doesn't always mention the bad things.) Some people have no symptoms whatsoever but a crackjack dr. pulls a random blood draw and it turns out after biopsy that they have celiac disease.

As far as I know of, none of my family has been diganosed with other autoimmune dieseses.

Some thoughts about inflammation. Celiac disease is an autoimmune inflammatory disease. One of the first physical objective findings is inflammation in the duodenum/small intestine. It can also cause inflammation and pain in the joints which will often lead to a correct or incorrect diagnosis of rheumatoid arthritis. From your description of your joint pain I do not suspect full-blown arthritis is the case with you, but you should pursue with a rheumatologist just in case.

In my case I had very high inflammatory markers on sed. rate and CRP, but I tested negative for Rheumatoid Factor (RF). Nevertheless, I was progressively diagnosed (because my x-rays showed joint involvement) with polymyalgia rheumatica, then non-RF rheumatoid arthritis, and eventually psoriatic arthritis when the psoriasis "bloomed". PsA is often RF-negative. So I was never completely sure how much of my inflammation came from my arthritis and how much came from my presumed celiac, and I say presumed since I was never tested, having gone gluten free in an attempt to manage my arthritis inflammation - the disappearance of my GI symptoms was really just an added bonus at that point, my arthritis having become that bad. Many doctors (although not mine) recommend a gluten free diet for rheumatoid-type conditions. I have also eliminated the nightshade family (potatoes, tomatoes, eggplant, bell peppers mainly) from my diet since they are pro-inflammatory. I had low B12, low folate, low D; I also have hypothyroidism, but it is 'subclinical', i.e., just within the (now old) guidelines but the symptoms respond to treatment.

When your doctor tested your thyroid did he do the TPO ab test? Have you had any ANA testing?

I didn't realize that Celiac disease was an inflammartory autoimmune disease...very interesting!

Both my sed. rate and CRP tests came back high and same as you, my RF tested negative. My TPO ab test was 17.3 with the standard range being <35 (according the my lab results) and the ANA was negative.

Thanks for all the information and thoughts! I am anxious and ready for my appointment to be here :)

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