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elissam5

Member Since 24 Apr 2013
Offline Last Active Aug 31 2014 10:17 AM
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Topics I've Started

Confused About Test Results

17 June 2013 - 04:49 PM

I've been experiencing some Celiac-like symptoms for a while now and could use some help making sense of these test results.

 

Some history:

 

I had a partial thyroidectomy 13 years ago (benign Follicular Adenoma).  I take Synthroid 112 mcg daily.  About 3 years ago, I starting experiencing hair loss, which my doctor attributed this to my throid and increased my synthroid.  Then, I starting having numbness in my feet.  My endo was concerned and ran what seemed like a million tests to discover that I was Vitamin B12 deficient.  She told me to take OTC megadoses and then retested me to find I was still deficient.  She prescribed B12 injections.  The B12 seems to have stabilized, but still isn't ideal.  Then, she tested my Vitamin D and found I was severally deficient there.  OTC prescribed with no improvement.  Prescription Vitamin D (50,000 Iu) every 7 days and then retested.  I was still deficient and now my calcium was dangerously low, probably due to low D.  Continued with the Vitamin D megadoses and then retested-both D and Calcium dangerously low and now my TSH is out of whack.  The endo had me increase the D to 50,000 Iu every 5 days and add 600 mg of Calcium every night.  She said she won't increase my Synthroid because she doesn't think I'm absorbing it and then referred me to a GI.

 

I meet with the Gi who asks me about other symptoms.  I report heartburn, flipping between consitpation and diarrhea, gas and bloating...He orders the blood test below and schedules an EGD.

 

Immunoglobulin A, Qn, Serum
87 mg/dL (70-400)

 

Deamidated Gliadin Abs, IgA
2 units (0-19)
Negative 0 - 19
Weak Positive 20 - 30
Moderate to Strong Positive >30

 

Deamidated Gliadin Abs, IgG
3 units (0-19)
Negative 0 - 19
Weak Positive 20 - 30
Moderate to Strong Positive >30

 

t-Transglutaminase (tTG) IgA
<2 U/mL (0-3)
Negative 0 - 3
Weak Positive 4 - 10
Positive >10

t-Transglutaminase (tTG) IgG
<2 U/mL (0-5)
Negative 0 - 5
Weak Positive 6 - 9
Positive >9

 

Endomysial IgA  Negative

 

After the EGD, the GI tells me that I have esophagitis and a gastric ulcer.  They pulled tissue samples for a biopsy.  He started me on a PPI to heal the ulcer.  I heard from the nurse practitioner today, my biopsy results show lympohcytes indicative of early Celiac Disease but I have negative blood tests.  I return to the doctor this Wednesday.

 

Does anyone have any idea what this means?