In terms of genetic testing, my thoughts on that may differ from what other members would recommend. Since my daughter's celiac panel and biopsy were positive, she had a firm diagnosis so we did not consider the genetic test for her. However, I was also like a walking textbook case of celiac (except that I was always a tall kid too), with symptoms going back to early childhood. When my daughter was diagnosed, everyone - including all my doctors - thought for sure I'd test positive too. Right before my biopsy, though, I had the genetic test and it showed that I only had one allele of the common DQ2 celiac gene. The genetics is complicated, but with the other allele the upshot is that I have the DQ7.5 gene (which is recognized among some celiac experts as another celiac gene but isn't generally considered one in the U.S.), but only half of a more commonly-recognized celiac gene. As a result, my doctors stopped taking the possiblity of celiac as seriously. Despite assuring me repeatedly before my biopsy that she's take "plenty" of samples, my GI only took four, with none from the duodenal bulb and no lymphocyte counts, because the genetic tests essentially led her to look elsewhere (even though there are documented causes of celiac with just one allele, and with DQ7). I suppose the genetic tests may be helpful if everything else is negative, but I'd push for a biopsy first.