Suzanne - Rachelle is right! It is worth looking at family history for autoimmune clues, particularly if like me and people posting here you have no obvious celiac symptoms. My brother died of lymphoma due to celiac which was diagnosed after 14 years of symptoms - anemia + abdominal. Our mother suffered from rickets as a child and thyrotoxicosis. She always had cold hands and feet sometimes progressing to chilblains, and several years of dementia. Her mother died aged 52 of diabetes and her maternal grandmother had two sibs who died in childhood. If it is unexplained it may well be autoimmune, and if it is autoimmune it may be related to celiac!