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Member Since 12 Apr 2014
Offline Last Active May 12 2014 11:41 AM

Topics I've Started

Blood Results Not Celiac, Could It Be Gluten Sensitivity?

12 May 2014 - 11:36 AM

My blood work is finally back and I am not positive for celiac disease, however I'm wondering if there's any indication of possible sensitivity.

tTG IgA <2 (reference 0-3)
Gliadin Peptide IgA 16 (reference 0-19)
Gliadin Peptide IgG 2 (reference 0-19)

Obviously none of my tests are positive and they didn't my total IgA levels like I had requested. I'm not sure whether or not the elevated IgA levels mean anything or if I'm just plain old good to go.

Thank you!

2 Year Old, No Visible Intestinal Damage, Waiting On Pathology

26 April 2014 - 11:27 AM

My 2 year old underwent an endoscopy and sigmoidoscopy on Wednesday. The doctor said everything looked good, nothing to be concerned about, and we'll have to see what the pathology report says in 2 weeks. I'm curious how likely it is that she could have celiac disease with there being no visible concerns to the doctor. I'm assuming that because of her age there's a strong likelihood that the damage wouldn't be extensive enough to be visible to the naked eye? Her blood tests were all negative (I wasn't given exact numbers, just says "negative"), but we were told that is common in young children. Between the blood results and the doctors visual assessment of her intestines I'm beginning to think it's very unlikely that she has celiac disease. If she doesn't then I don't know where else to turn to explain her "failure to thrive", distended abdomen, pain, excessive gas, constipation, diarrhea, irritability, etc :-(

Negative Ttg Iga Without Total Iga Count?

26 April 2014 - 10:58 AM

My primary care doctor ordered a tTG IgA and a DGP IgG upon my request. I specifically requested a total IgA (technically I requested a FULL panel and specified a total IgA) , but it appears it wasn't ordered. After 2 weeks I have finally received the tTG IgA results and am still waiting on the DGP IgG results. The tTG IgA says this:

Tissue Transglutaminase Ab. IgA, Serum Quantitative
Result <2 U/mL
Reference Range 0-3

Obviously the result is negative, but without the total IgA count how much weight should I give to this result? I know there is some possibility that I could be IgA deficient, but what's the likelihood that this is a false negative without knowing my total IgA status? The doctor seemed very dismissive of my request for a celiac panel. I'm concerned that if my DGP is positive that she'll dismiss it due to the negative tTG IgA (I'm having this problem with my 5 year old who tested negative DGP IgA and weak positive DGP IgG). Thoughts?

Thank you!

Help Understanding Blood Results

12 April 2014 - 04:28 PM

I'm completely overwhelmed trying to understand all of these tests/results and what the doctors are telling me. I really appreciate any help you can offer!

Two of my daughters are currently undergoing testing for celiacs.

My 2 year old is "failure to thrive". She's below the 3rd percentile in weight (she was 8lbs 12oz at birth), greasy and mucousy stools, alternating constipation and diarrhea, extremely distended abdomen with the skinniest little arms and legs, speech delay, extreme irritability, etc. Her celiac blood panel came back negative (actual numbers aren't listed on the lab work), her vitamin levels are all the lowest possible levels within the normal range (in other words, none are in the low range but they're JUST within normal), her alkaline phosphatase and white blood count were high (not extremely). She tested negative for cystic fibrosis. She is scheduled for an endoscopy and sigmoidoscopy in 2 weeks. Her GI said that the blood work is very unreliable in a child who has just recently turned 2 years old.

My 5 year old has been struggling with chronic constipation and UTIs. Over the last 2 years she has developed a rash that comes and goes (circles of what the doctor has diagnosed as eczema on the trunk of her body, arms, and knees). Over the last month she has begun complaining of severe abdominal pain. She will randomly begin to scream and clench her belly. The doctor said she was constipated and put her on miralax. After a month on miralax and her stools coming soft and regularly she is still complaining of abdominal pain. Now that she is no longer constipated we have noticed that her stools are a pale sort of yellow orange and they float. Her primary care doctor drew her blood last week and her DGP IgA was 4 (0-19 normal), her DGP IgG was 20 (0-19 normal), the endomysium titer was negative <1:10. I am still waiting (over a week) for the doctor to call me and explain the results, but the nurse said everything looks normal.

Everything I can find makes me think that the 5 year old's DGP IgG being high should warrant further investigation. I want to be prepared when the doctor calls in case he also tells me everything is normal. Is it likely that either of my children could have celiacs based on the results we've gotten thus far or does it seem unlikely?

I appreciate your thoughts and advice!