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      Frequently Asked Questions About Celiac Disease   04/07/2018

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes
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    LARGE NUMBER OF IRRITABLE BOWEL SYNDROME PATIENTS SENSITIVE TO GLUTEN


    Jefferson Adams

    Celiac.com 07/29/2015 - Numerous studies have shown that a high percentage of patients with irritable bowel syndrome (IBS) are also sensitive to gluten. 


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    Photo: CC--Nana B. AgyeiA team of researchers recently set out to evaluate the effect of a gluten-free diet on gastrointestinal symptoms in patients with IBS. The research team included B. Shahbazkhani, A. Sadeghi, R. Malekzadeh, F. Khatavi, M. Etemadi, E. Kalantri, M. Rostami-Nejad, and K. Rostami.

    They are variously affiliated with the Gastroenterology Unit of Imam Khomeini Hospital at the Tehran University of Medical Sciences, Tehran, Iran, the Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran, the Sasan Alborz Biomedical Research Center, Masoud Gastroenterology and Hepatology Clinic, Tehran, Iran, the Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran, the Gholhak Medical Laboratory, Tehran, Iran, the Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, and with the Department of Gastroenterology, Alexandra Hospital, Worcestershire, UK.

    For their double-blind randomized, placebo-controlled trial, the team enrolled 148 IBS patients who fulfilled Rome III criteria between 2011 and 2013.

    Unfortunately, only 72 out of the 148 remained on a gluten-free diet for the six weeks needed to complete the study.

    The team recorded clinical symptoms biweekly using a standard visual analogue scale (VAS).

    In the second stage after six weeks, patients whose symptoms improved to an acceptable level were randomly divided into two groups; The first group of 35 patients received packages containing powdered gluten, while 37 patients received a gluten-free placebo powder.

    Nearly 84% of the gluten-free placebo group showed a significant improvement in symptoms compared to just under 26% for the gluten consuming group (p < 0.001).

    This study confirms that a large number of patients diagnosed with irritable bowel syndrome are sensitive to gluten.

    The team suggests that the term of IBS might be misleading and may change or delay an "effective and well-targeted treatment strategy in gluten sensitive patients."

    Source:


    Image Caption: Photo: CC--Nana B. Agyei
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    Guest Glinda

    Posted

    Really? This is news? IBS is doctor's code for I Be Stumped, and I won't be digging any deeper to try to help you figure out the cause. Now take this hyoscyamine and deal.

    I'm an RN with celiac disease and have a son with celiac disease...any time I have a patient who has GI symptoms and autoimmune disease, I always insist on testing for celiac disease. And the funniest thing is that when I start to ask about family history, it almost always pops up that one family member has celiac or gluten intolerance but none of the extended family was ever tested. Still a huge lack of understanding and awareness in the medical community.

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    Guest Debbie

    Posted

    Really? This is news? IBS is doctor's code for I Be Stumped, and I won't be digging any deeper to try to help you figure out the cause. Now take this hyoscyamine and deal.

    I'm an RN with celiac disease and have a son with celiac disease...any time I have a patient who has GI symptoms and autoimmune disease, I always insist on testing for celiac disease. And the funniest thing is that when I start to ask about family history, it almost always pops up that one family member has celiac or gluten intolerance but none of the extended family was ever tested. Still a huge lack of understanding and awareness in the medical community.

    I went gluten free after figuring it out for myself. I'm an RN as well. Refused to go back on gluten to have a test tell me what I already found out! Husband has had IBS his whole life. Got amazingly better on the gluten-free diet and suffered horribly when visiting relatives and ate what he wanted! Proof Positive... no further testing needed!!

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    Thanks for article! I also have IBS-C for five years and it is very hard to deal with this condition.

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    Diana Gitig Ph.D.
    Celiac.com 05/18/2011 - Irritable Bowel Syndrome (IBS) is based on a clinical description only; there are no pathophysiological pathways definitively associated with it. It is characterized as gastrointestinal symptoms with no discernable cause. A diagnosis of IBS depends on recurrent abdominal pain or discomfort for at least three days per month in the last three months, with the onset of the discomfort either associated with a change in frequency or appearance of stool or alleviated by defecation. A number of different mechanisms have been suggested as potential causes of IBS. These range from psychological origins, to increased visceral hyperalgesia (sensitivity to pain), to the low grade gut inflammation and altered gastrointestinal permeability and motility observed in IBS patients. Complicating matters is that most patients exhibit only a subset of symptoms. Since gluten has been demonstrated to negatively affect even people without celiac disease by an unknown mechanism (see Study Shows Gluten Intolerance Without Celiac Disease), and the underlying causes of IBS remain unclear, Dr. Elena Verdu wondered if gluten might contribute to IBS.
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    Am J Gastroenterol 2011; 106:516–518

    Jefferson Adams
    Celiac.com 02/25/2013 - Patients with celiac disease often report symptoms compatible with irritable bowel syndrome (IBS). However, there haven't been any systematic studies regarding how adherence to a gluten-free diet might affect rates of irritable bowel syndrome-type symptoms in patients with celiac disease.
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    Source:
    Clin Gastroenterol Hepatol. 2012 Dec 13. pii: S1542-3565(12)01491-7. doi: 10.1016/j.cgh.2012.11.033.

    Jefferson Adams
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    Jefferson Adams
    Celiac.com 06/04/2015 - Some researchers feel that people who self report non-celiac gluten sensitivity (SR-NCGS) and also follow a gluten-free diet might actually fall within the spectrum of irritable bowel (IBS). Interestingly, recent reports suggest that large numbers of people with inflammatory bowel disease (IBD) also follow a gluten-free diet.
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    Source:
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    Jefferson Adams
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    Connie Sarros
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    Jefferson Adams
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    cnbc.com