Further: Sarcoidosis was once considered a rare disease. It is now known to be a common chronic illness that appears all over the world. It is the most common of the fibrotic lung disorders, and occurs often enough in the United States for Congress to have declared a national Sarcoidosis Awareness Day in 1990. Sarcoidosis is currently (1993) thought to be associated with an abnormal immune response. Whether a foreign substance; a chemical, drug, virus, or some other substance is the trigger and how the immune disturbance is caused are not known. No one can predict how sarcoidosis will progress. In general, sarcoidosis appears briefly and heals naturally. However, 20 to 30% of sarcoidosis patients are left with some permanent lung damage. In 10 to 15% of the patients, sarcoidosis can become severe and chronic. When either the granulomas or fibrosis seriously affect the function of a vital organ; the lungs, heart, nervous system, liver, or kidneys, for example, sarcoidosis can be fatal.
From Ron Hoggan:
Sarcoidosis has repeatedly been associated with celiac disease. Some researchers seem to view it as a condition which results from untreated celiac disease, while others see it as coincident with celiac disease. Here are a couple of references you might want to look at:
- Douglas, et. al. Sarcoidosis and Celiac Disease: An Association? Lancet, 1984; July 7:13-15
- Karlish Celiac Disease and Diffuse Lung Disease Lancet, 1971; May 22: 1077
A Medline search might reveal more information to you, and I would suggest that you satisfy yourself of the connection. In #1, it says, in part: These cases suggest there may be an association between celiac disease and sarcoidosis, but formal studies of small bowel function in sarcoidosis are needed to confirm this. It is important to recognize that these two conditions can occur together and that unexplained weight loss in a patient with sarcoidosis may be caused by celiac disease. You might consider suggesting that your friend get a full panel of blood tests for celiac disease, as it is usually a very treatable condition. And I have been pleasantly surprised by the resolution of other, apparently unrelated health problems, that have cleared up on the diet since I was diagnosed. I hope she is similarly surprised.
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- Bianconcini G, et al. [see Related Articles] [Celiac disease (familial) associated with sarcoidosis. Clinical case and review of the literature]. Minerva Med. 1994 Oct; 85(10): 541-553. Review. Italian. PMID: 7800197; UI: 95098301.
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- [No authors listed] [see Related Articles] Sarcoidosis and celiac disease. Lancet. 1984 Aug 18; 2(8399): 408. No abstract available. PMID: 6147488; UI: 84294274.
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- Karlish AJ, et al. [see Related Articles] The Kveim test in Crohns disease, ulcerative colitis, and celiac disease. Lancet. 1972 Feb 19; 1(7747): 438-439. No abstract available. PMID: 4110670; UI: 72118038.
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