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      Frequently Asked Questions About Celiac Disease   04/24/2018

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What is Celiac Disease and the Gluten-Free Diet? What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes
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    GLUTEN TIED TO SCHIZOPHRENIA


    Jefferson Adams

    Celiac.com 04/29/2009 - A team of researchers based at UK's prospective University of Highlands and Islands (UHI) have found a link between gluten and schizophrenia. According to their latest findings, proteins found in the gluten of wheat, rye and barley might play a role in triggering schizophrenia in people with a genetic risk for the condition, or in worsening symptoms in people who have the disease.


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    The research team has been looking into the role played by gluten in schizophrenia and diabetes, as well as hunting for connections between the two disorders. Their research showed that the bodies of certain schizophrenia sufferers could not properly processes gluten, which led to tissue damage.

    As a result of these and other findings, researchers now consider genetic risk factors, together with environmental triggers, to be central to development of both schizophrenia and diabetes. Gluten is one such example.

    According to senior researcher and reader in genetics, Dr. Jun Wei, more than one-third of all people with schizophrenia show "high levels of antibodies against wheat gluten," and may experience some improvement in symptoms with a gluten-free diet.

    Though the studies are still in their early stages, the hypothesis is encouraging, because, as noted by head of UHI department of diabetes and cardiovascular science, Prof Ian Megson, if it is correct, "a simple change in diet might prevent these diseases...in some individuals."

    The research is part of two comprehensive studies at UHI into the connections between schizophrenia and diabetes, and the role played by gluten, and is supported by a £300,000 grant from the Schizophrenia Association of Great Britain (SAGB).

    It would be interesting to see more research done on the connection between celiac disease and schizophrenia, as other studies have indicated that there is a link.


    Source: BBC News


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    Guest Carol Lynde

    Posted

    I have believed this all along. I have seen what gluten does to a very dear relative of mine.

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    Guest Terrie Martin

    Posted

    I found an article years ago, with information on vitamin therapy and schizophrenia, it was fantastic, this should be looked at as a real cure, or a type care management. The medical community is so very slow to get the necessary resources out. What a shame for the people with this terrible problem.

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    Guest Rebecca Paul

    Posted

    I was amazed to read this article! My mother and two of her sisters are celiacs and have schizophrenia. I am also a celiac and fortunately have had no symptoms of schizophrenia, but suffer from depression and anxiety, another possible connection to celiac disease. I hope the doctors are paying attention to this issue.

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    Guest Dee

    Posted

    Interesting concept. I have type 1 diabetes (32 yrs.) and 2 yrs. ago was diagnosed with celiac disease however, not schizophrenia, thankfully. I suppose when hypoglycemia occurs, it may appear that way until the sugars are up! There is a link between diabetes and celiac disease due to the gastro track/digestive common areas however, I never heard of the schizophrenia link. I work in a field of mental health and autism (biochemical disorders) where step one to our patients is removing gluten and, often times, casein, the protein in milk products. I'll be very interested to follow this story when the ongoing research described is completed.

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    Guest Mark Carlson

    Posted

    Wouldn't it be nice if our health care system was actually 'health driven' rather than 'profit driven'? Scientific research has already shown that nutrition and mental illness often go hand in hand. For instance, the little known illness called Pyroluria, which is a simple nutritional deficiency, contributes to mental illness (and may be related to celiac disease). Just think - if we could just adjust a few nutritional deficiencies, many of these people could be cured or at least helped.

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    Guest Auroch

    Posted

    Two days without gluten or milk and I've stopped hallucinating and I actually feel like being nice to people. If you try to tell a doctor that you don't want their Risperdal and that their pills can't fix the problem they automatically say your psychotic for disagree with someone who has a MD. Anyone with schizophrenia who is tired of living in hell should try this, a 1/3 success rate is better than most meds. Why did science discover a hundred different anti-psychotics before this?

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    Guest Teresa

    Posted

    I have celiac and dermatitis herpetiformis and was able to convince my niece to be tested. Her test came back positive, however no one else in my family is interested in getting tested. My dad has terrible mood swings, alcoholism (there is a link to that as well), trouble relating to people and lactose intolerance. My sister has rhuematoid arthritis, anxiety, panic attacks, etc. and had a doctor tell her that she was crazy and needed to check herself into a mental hospital. Another sister has eczema and short stature, another sister has psoriasis, my younger brother has ADD and my older brother has schizophrenia and alcoholism and has been living homeless for years. He is now incarcerated. My life has changed dramatically since going gluten-free 2.5 years ago. I am convinced that this disease is running rampant through my family as well as many other families, and it is ruining lives. Just in the last 7 months I found my older brother, I hadn't seen him in 18 years, he just disappeared. His life is a mess and I can't help but believe that gluten is just eating his body and his mind. This is a sad epidemic. Having just found my brother I just found out about his schizophrenia. Something needs to be done, I am going to do everything I can to see that changes are made. I'm at the beginning of my journey but I am determined!

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    Guest Susanne

    Posted

    I have celiac and dermatitis herpetiformis and was able to convince my niece to be tested. Her test came back positive, however no one else in my family is interested in getting tested. My dad has terrible mood swings, alcoholism (there is a link to that as well), trouble relating to people and lactose intolerance. My sister has rhuematoid arthritis, anxiety, panic attacks, etc. and had a doctor tell her that she was crazy and needed to check herself into a mental hospital. Another sister has eczema and short stature, another sister has psoriasis, my younger brother has ADD and my older brother has schizophrenia and alcoholism and has been living homeless for years. He is now incarcerated. My life has changed dramatically since going gluten-free 2.5 years ago. I am convinced that this disease is running rampant through my family as well as many other families, and it is ruining lives. Just in the last 7 months I found my older brother, I hadn't seen him in 18 years, he just disappeared. His life is a mess and I can't help but believe that gluten is just eating his body and his mind. This is a sad epidemic. Having just found my brother I just found out about his schizophrenia. Something needs to be done, I am going to do everything I can to see that changes are made. I'm at the beginning of my journey but I am determined!

    Teresa,

     

    My son (22) is diagnosed with schizoaffective psychotic disorder. I am very curious about getting him allergy tested and talking him into trying gluten-free. He is in denial, yet he knows he's unhappy. I am wondering how far you have gotten with your research. My older brother and dad showed signs as well when I was growing up. Today, my older brother is mega-obese and hyper when we talk on the phone. I have dealt with depression especially bad as a child. I seem to have a grip on it now. B-12 Methylcobalimin 2000-5000 mcg. a day.

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    Guest Albert

    Posted

    I have celiac and dermatitis herpetiformis and was able to convince my niece to be tested. Her test came back positive, however no one else in my family is interested in getting tested. My dad has terrible mood swings, alcoholism (there is a link to that as well), trouble relating to people and lactose intolerance. My sister has rhuematoid arthritis, anxiety, panic attacks, etc. and had a doctor tell her that she was crazy and needed to check herself into a mental hospital. Another sister has eczema and short stature, another sister has psoriasis, my younger brother has ADD and my older brother has schizophrenia and alcoholism and has been living homeless for years. He is now incarcerated. My life has changed dramatically since going gluten-free 2.5 years ago. I am convinced that this disease is running rampant through my family as well as many other families, and it is ruining lives. Just in the last 7 months I found my older brother, I hadn't seen him in 18 years, he just disappeared. His life is a mess and I can't help but believe that gluten is just eating his body and his mind. This is a sad epidemic. Having just found my brother I just found out about his schizophrenia. Something needs to be done, I am going to do everything I can to see that changes are made. I'm at the beginning of my journey but I am determined!

    Gluten is a big business; therefore it is untouchable. The problem is that even sciences are dragged in it. There is no reliable test for gluten sensitivity. I am gluten free 22 years; without doctor's blessing. Years ego Dr Fasano published that human digesting system is not able process it. They can not develop test for gluten sensitivity. And I would bet whole quarter that it will be never developed; for simple reason. We are all sensitive to that stuff; some more; some less. Find a test is witch hunt, which leading to nowhere. In my long life I seen too much suffering and premature deaths. I am sloughing when I reading results of survey. They compare people diagnosed with celiac disease with "healthy" people. I am just wandering haw they declare anybody to be "healthy" when they can not prove with test. I asked this question few of specialists in celiac disease. I never have got reply. It must be well guarded secret. Anyway: it is cruel world out there.

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    BMJ 2004;328:438-439 (21 February) Celiac.com 02/27/2004 – The following report is interesting, but I believe that serological studies done on those with schizophrenia would be a far better way to conduct such a study. Also, the use of such a small control group cannot accurately predict the actual incidence of schizophrenia in those with celiac disease. –Scott Adams
    According to a Danish study published in the British Medical Journal, people with celiac disease may have an increased risk of developing schizophrenia. Previous studies have also suggested an association between these two disorders. The study identified 7,997 people over age 15 who were admitted to a Danish psychiatric unit for the first time between 1981 and 1998 and were diagnosed with schizophrenia. The researchers selected 25 random controls and matched their year of birth and sex, and identified any history of celiac disease, ulcerative colitis or Crohns disease in both groups, and in their parents. A "moderately strong risk relation between coeliac disease and schizophrenia" was discovered in the data, and the researchers stress that these findings only reflect a small proportion of cases, as both disorders are rare. The prevalence of celiac disease among schizophrenics was 1.5 cases per 1,000 compared to 0.5 cases per 1,000 in the larger control group, which means that there is a three times greater risk of schizophrenia in those with celiac disease. Interestingly Crohns disease and ulcerative colitis were not associated with an increased risk of schizophrenia.
    According to Dr. Eaton: More research is needed to understand the link between celiac disease and schizophrenia. The most important question is whether treatment for celiac disease, in the form of a gluten-free diet, would benefit the small proportion of individuals with schizophrenia who are genetically prone to celiac disease but have not been diagnosed with it."

    Jefferson Adams
    Celiac.com 07/13/2009 - Doctors are recommending that kids with mental and behavioral disorders, and with low cholesterol be tested for celiac disease.
    This, after findings from a recent study suggest that low plasma cholesterol levels might have a role in the development and pathogenesis of certain behavioral disorders such as schizophrenia, depression, and obsessional neurosis in people with celiac disease.
    It is well documented that children with celiac disease face higher rates of certain behavioral disorders such as schizophrenia, depression, and obsessional neurosis. Still, not much is known about the development and pathogenesis of celiac-related mental and behavioral disorders.
    A team of researchers made up of Italians Luca Mascitelli, M.D., Francesca Pezzetta, M.D., and American Mark R. Goldstein, M.D. set out to investigate the matter.
    A large scale study of patients aged 6–16 years showed that most people with celiac disease harbored illness of low-grade intensity that was often associated with "decreased psychophysical well-being."
    Furthermore, a recent study found that adolescents with celiac disease face higher rates of depressive and disruptive behavioral disorders, especially before adopting a gluten-free diet. 2 For some, psychiatric symptoms appear to improve after the patients started a gluten-free diet.
    Interestingly, children with malabsorption and steatorrhea due to celiac disease often have lower concentrations of blood cholesterol. Moreover, people with celiac disease, but who show no signs of overt cholesterol malabsorption, often show low levels of blood cholesterol, while normal to high cholesterol levels have been shown effective in ruling out celiac disease.
    Add to that the fact that low cholesterol has been tied to other mental disorders. In particular, a national sample of non-institutionalized, non-African American children of school-age found a statistically significant association between low cholesterol and aggressive behavior.
    Low cholesterol has also been tied to the onset of conduct disorder during childhood among male criminals. Therefore, they recommend that screening for celiac disease be considered in children and adolescents with mental disorders and low cholesterol.
    Psychosomatics 50:300-301, May-June


    Jefferson Adams
    Celiac.com 02/13/2013 - A team of researchers wanted to determine whether levels of immunoglobulin G (IgG) were associated with a later diagnosis of a non-affective psychotic disorder.
    The researchers included H. Karlsson, Å. Blomström, S. Wicks, S. Yang, R.H. Yolken, and C. Dalman. They are affiliated with the Department of Neuroscience at the Karolinska Institute in Stockholm, Sweden.
    To accomplish their goal, the team analyzed archival dried blood spots taken from newborns in Sweden between 1975 and 1985 with verified register-based diagnoses of non-affective psychoses made between 1987 and 2003 and comparison subjects matched on sex, date of birth, birth hospital, and municipality.
    The team reviewed samples from a total of 211 case subjects and 553 comparison subjects who agreed to take part in the study. They pulled data for factors associated with maternal status, pregnancy, and delivery from the Swedish Medical Birth Register.
    They used enzyme-linked immunosorbent assay to analyze the results for levels of IgG directed at gliadin (a component of gluten) and casein (a milk protein) in eluates from dried blood spots. They then calculated odds ratios for levels of IgG directed at gliadin or casein for non-affective psychosis.
    Comparison subjects associated with non-affective psychosis showed levels of anti-gliadin IgG (but not anti-casein IgG) above the 90th percentile of levels observed (odds ratio=1.7, 95% CI=1.1-2.8).
    This connections was not affected by differences in maternal age, immigrant status, or mode of delivery. They also found that gestational age at birth, ponderal index, and birth weight were not associated with maternal levels of anti-gliadin IgG.
    From their study, they concluded that high levels of anti-gliadin IgG in the maternal circulation are associated with an elevated risk for the development of a non-affective psychosis in offspring.
    They point out that more research is needed to identify the mechanisms underlying this association in order to develop preventive strategies.
    Source:
    Am J Psychiatry. 2012 Jun;169(6):625-32. doi: 10.1176/appi.ajp.2012.11081197.

    Jefferson Adams
    Celiac.com 05/29/2014 - Many people with celiac disease report symptoms of depression, which usually subside upon treatment with a gluten-free diet. But a new study out of Australia suggests that gluten can cause depression in people with non-celiac gluten-sensitivity.
    Current evidence shows that many patients with self-reported non-celiac gluten sensitivity (NCGS) continue to have gastrointestinal symptoms on a gluten-free diet, but say that avoiding gluten makes them feel ‘better'. So, why do people with non-celiac gluten sensitivity seem to feel better on a gluten-free diet, even if they still have gastrointestinal symptoms? A team of researchers wanted to know if this might be due to gluten’s effects on the mental state of those with NCGS, and not necessarily because of gastrointestinal symptoms.
    The research team included S. L. Peters, J. R. Biesiekierski, G. W. Yelland, J. G. Muir, and P. R. Gibson. They are affiliated with the Department of Gastroenterology, Central Clinical School of Monash University at The Alfred Hospital in Melbourne, the Department of Gastroenterology at the Eastern Health Clinical School of Monash University in Box Hill, and the School of Health Sciences at RMIT University in Bundoora, Victoria, Australia.
    For their double-blind cross-over study, they looked at 17 women and five men, aged 24–62 years. All participants suffered from irritable bowel syndrome, but not from celiac disease, and their symptoms were controlled on a gluten-free diet. The team gave the participants one of three random dietary challenges over 3 days, followed by a minimum 3-day washout before moving to the next diet. All participants got all three diets over the course of the study.
    For each phase, the team supplemented the challenge gluten-free food with gluten, (16 g/day), whey (16 g/day) or nothing at all (placebo). The team assessed mental state as determined by the Spielberger State Trait Personality Inventory (STPI), cortisol secretion and gastrointestinal symptoms.
    They found that gluten ingestion was associated with higher overall STPI state depression scores compared to placebo [M = 2.03, 95% CI (0.55–3.51), P = 0.010], but not whey [M = 1.48, 95% CI (−0.14 to 3.10), P = 0.07]. They found no differences for other STPI state indices or for any STPI trait measures, and they saw no difference in cortisol secretion between challenges. Gastrointestinal symptoms were similar for each dietary challenge.
    Short-term exposure to gluten specifically induced current feelings of depression with no effect on other indices or on emotional disposition. Moreover, the team saw no gluten-specific trigger of gastrointestinal symptoms. Such findings might explain why patients with non-coeliac gluten sensitivity feel better on a gluten-free diet despite the continuation of gastrointestinal symptoms.
    Source:
    Aliment Pharmacol Ther. 2014;39(10):1104-1112.

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    Jefferson Adams
    Celiac.com 04/25/2018 - A team of Yale University researchers discovered that bacteria in the small intestine can travel to other organs and trigger an autoimmune response. In this case, they looked at Enterococcus gallinarum, which can travel beyond the gut to the spleen, lymph nodes, and liver. The research could be helpful for treating type 1 diabetes, lupus, and celiac disease.
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    Celiac.com 04/24/2018 - Did you know in 2017 alone, the United States had OVER TENS OF THOUSANDS of people evacuate their homes due to natural disasters such as fires, floods, hurricanes, tornadoes and tsunamis? Most evacuation sites are not equipped to feed your family the safe gluten free foods that are required to stay healthy.  Are you prepared in case of an emergency? Do you have your Gluten Free Emergency Food Bag ready to grab and go?  
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    In 2017 alone, FEMA (Federal Emergency Management Agency) had 137 natural disasters declared within the United States. According to FEMA, around 50% of the United States population isn’t prepared for a natural disaster. These disasters can happen anywhere, anytime and some without notice. It’s hard enough being a parent, let alone being a parent of a gluten free family member. Now, add a natural disaster on top of that. Are you prepared?
    You can find my Gluten Free Emergency Food Bags and other useful products at www.allergynavigator.com.  

    Jefferson Adams
    Celiac.com 04/23/2018 - A team of researchers recently set out to learn whether celiac disease patients commonly suffer cognitive impairment at the time they are diagnosed, and to compare their cognitive performance with non-celiac subjects with similar chronic symptoms and to a group of healthy control subjects.
    The research team included G Longarini, P Richly, MP Temprano, AF Costa, H Vázquez, ML Moreno, S Niveloni, P López, E Smecuol, R Mazure, A González, E Mauriño, and JC Bai. They are variously associated with the Small Bowel Section, Department of Medicine, Dr. C. Bonorino Udaondo Gastroenterology Hospital; Neurocience Cognitive and Traslational Institute (INECO), Favaloro Fundation, CONICET, Buenos Aires; the Brain Health Center (CESAL), Quilmes, Argentina; the Research Council, MSAL, CABA; and with the Research Institute, School of Medicine, Universidad del Salvador.
    The team enrolled fifty adults with symptoms and indications of celiac disease in a prospective cohort without regard to the final diagnosis.  At baseline, all individuals underwent cognitive functional and psychological evaluation. The team then compared celiac disease patients with subjects without celiac disease, and with healthy controls matched by sex, age, and education.
    Celiac disease patients had similar cognitive performance and anxiety, but no significant differences in depression scores compared with disease controls.
    A total of thirty-three subjects were diagnosed with celiac disease. Compared with the 26 healthy control subjects, the 17 celiac disease subjects, and the 17 disease control subjects, who mostly had irritable bowel syndrome, showed impaired cognitive performance (P=0.02 and P=0.04, respectively), functional impairment (P<0.01), and higher depression (P<0.01). 
    From their data, the team noted that any abnormal cognitive functions they saw in adults with newly diagnosed celiac disease did not seem not to be a result of the disease itself. 
    Their results indicate that cognitive dysfunction in celiac patients could be related to long-term symptoms from chronic disease, in general.
    Source:
    J Clin Gastroenterol. 2018 Mar 1. doi: 10.1097/MCG.0000000000001018.

    Connie Sarros
    Celiac.com 04/21/2018 - Dear Friends and Readers,
    I have been writing articles for Scott Adams since the 2002 Summer Issue of the Scott-Free Press. The Scott-Free Press evolved into the Journal of Gluten Sensitivity. I felt honored when Scott asked me ten years ago to contribute to his quarterly journal and it's been a privilege to write articles for his publication ever since.
    Due to personal health reasons and restrictions, I find that I need to retire. My husband and I can no longer travel the country speaking at conferences and to support groups (which we dearly loved to do) nor can I commit to writing more books, articles, or menus. Consequently, I will no longer be contributing articles to the Journal of Gluten Sensitivity. 
    My following books will still be available at Amazon.com:
    Gluten-free Cooking for Dummies Student's Vegetarian Cookbook for Dummies Wheat-free Gluten-free Dessert Cookbook Wheat-free Gluten-free Reduced Calorie Cookbook Wheat-free Gluten-free Cookbook for Kids and Busy Adults (revised version) My first book was published in 1996. My journey since then has been incredible. I have met so many in the celiac community and I feel blessed to be able to call you friends. Many of you have told me that I helped to change your life – let me assure you that your kind words, your phone calls, your thoughtful notes, and your feedback throughout the years have had a vital impact on my life, too. Thank you for all of your support through these years.

    Jefferson Adams
    Celiac.com 04/20/2018 - A digital media company and a label data company are teaming up to help major manufacturers target, reach and convert their desired shoppers based on dietary needs, such as gluten-free diet. The deal could bring synergy in emerging markets such as the gluten-free and allergen-free markets, which represent major growth sectors in the global food industry. 
    Under the deal, personalized digital media company Catalina will be joining forces with Label Insight. Catalina uses consumer purchases data to target shoppers on a personal base, while Label Insight works with major companies like Kellogg, Betty Crocker, and Pepsi to provide insight on food label data to government, retailers, manufacturers and app developers.
    "Brands with very specific product benefits, gluten-free for example, require precise targeting to efficiently reach and convert their desired shoppers,” says Todd Morris, President of Catalina's Go-to-Market organization, adding that “Catalina offers the only purchase-based targeting solution with this capability.” 
    Label Insight’s clients include food and beverage giants such as Unilever, Ben & Jerry's, Lipton and Hellman’s. Label Insight technology has helped the Food and Drug Administration (FDA) build the sector’s very first scientifically accurate database of food ingredients, health attributes and claims.
    Morris says the joint partnership will allow Catalina to “enhance our dataset and further increase our ability to target shoppers who are currently buying - or have shown intent to buy - in these emerging categories,” including gluten-free, allergen-free, and other free-from foods.
    The deal will likely make for easier, more precise targeting of goods to consumers, and thus provide benefits for manufacturers and retailers looking to better serve their retail food customers, especially in specialty areas like gluten-free and allergen-free foods.
    Source:
    fdfworld.com