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      Frequently Asked Questions About Celiac Disease   04/07/2018

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes
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    CONNECTION FOUND BETWEEN CELIAC DISEASE AND HASHIMOTO'S THYROIDITIS


    Jefferson Adams

    Celiac.com 04/23/2007 - The results of a recent Dutch study published in the World Journal of Gastroenterology have confirmed a connection between Hashimotos Thyroiditis and celiac disease.


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    In the study, 104 individuals with Hashimotos Thyroiditis were tested for immunoglobulin A anti-transglutaminase (tTG) antibodies, IgA anti-endomysial antibodies (EMA) and HLA-DQ typing. Those who tested positive for any of the serological tests were given an intestinal biopsy.

    Sixteen patients (15%) showed positive celiac serology and five patients clear villous atrophy were diagnosed with celiac disease (4.8%; 95% CI 0.7-8.9). All five patients diagnosed with celiac disease, and 53 patients with Hashimotos thyroiditis (50%; 95% CI 43-62), showed the presence of HLA-DQ2 (and/or -DQ8).

    In a separate test within the study, 184 Individuals with known celiac disease were given a serological test for thyroglobulin and thyroid peroxidase Antibodies, after first being given thyroid biochemical, a thyroxine-free thyroid stimulating hormone.

    39 patients (21%) showed positive thyroid serology. According to thyroid biochemistry results, ten patients showed euthyroidism (5%; 95% CI 2-9), seven showed sub-clinical hypothyroidism (3.8%; 95% CI 1.8-7.6), and 22 patients showed overt hypothyroidism, Hashimotos thyroiditis (12%; 95% CI 8-16). Furthermore, four patients with celiac disease had Graves disease (2%; 95% CI 0.8-5) and one patient had post-partum thyroiditis.

    The study concludes that there is a clear association between Hashimotos thyroiditis and celiac disease. Accordingly, it is recommended that patients with Hashimotos thyroiditis be screened for celiac disease and that patients with known celiac be screened for Hashimotos thyroiditis.

    World Journal of Gastroenterology 2007; 13(10).

    health writer who lives in San Francisco and is a frequent author of articles for Celiac.com.


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    Guest colleen pike

    Posted

    For years I have suffered with Hashimoto's and could not understand why I could not loose weight on the oroxine medication even though I exercise and am active. Do you think a Gluten free diet could help me as I am 59 years old?

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    I have antibodies in my thyroid so I did an IgG food allergy test which showed I was allergic to many things such as meats, lettuce, peaches and gluten in wheat. The doctor told me to not worry about the gluten for now but to try to get off the other foods that I a allergic to. I did that for 2 months and my antibody count went from 500's to 300's. I think normal is 0-14. Then I asked him if I should go off gluten. He said yes. I feel better without gluten. I have been off it for about a week.

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    Guest Elinor F. Skeate

    Posted

    Interesting...since I had Hashimoto's about the same time I started getting celiac problems, though it has taken me 20 years to get a diagnosis of celiac.

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    Guest angela

    Posted

    I have Hashimoto's and in my research have learned that anyone with this disease is gluten intolerant - as with many autoimmune diseases.

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    Excellent info. I want to add that if your thryoid tests are within normal range, and you then go off gluten, you will most likely lose weight. At this point, your medication dosage may be too high for your reduced body mass. It's very important to be re-checking your thyroid hormones if you lose weight or change your diet as you could veer into hyperthyroidism, which is what happened to me along with all the messy symptoms. Stay on top of this, please.

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    Guest Genece Warren

    Posted

    I was finally diagnosed with celiac eight years ago, after suffering for 15 years before being diagnosed. I am also lactose intolerant. I have just been diagnosed with Hashimoto's disease and am so grateful to confirm that there is a correlation between celiac and Hashimoto's. Thank you so much for validating my suspicion.

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    Guest HDugas

    Posted

    I was diagnosed with celiac three years ago and just recently my new doctor diagnosed me with hypothyroidism. She didn't specify Hashimoto's but it would make sense. I start on Synthroid today, so hopefully I'll start to feel better.

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    I was diagnosed with Hashimoto's and Celiac's disease at the same time. I was 33 when I got my diagnosis. I just figured I was weird and had both issues, I am so glad (not really but you know what I mean) to see there are others out there like me!

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    I was diagnosed with Hashimoto's and within three months of being on Levothyroxine, I began to experience celiac symptoms. My TSH shot back up while on Levothyroxine which made me suspicious about my diet. I read somewhere that thyroid medication is absorbed in your lower intestines, and that is also where you find damage from gluten if gluten is a problem for you. So, if gluten is damaging your lower intestines, then your body cannot fully absorb the optimal thyroid dosage from the medication. I cut gluten and all my hypo symptoms went away and my TSH has begun to go down again. However, if I do slip on the gluten-free diet (because it's really hard to stay on if you don't have an immediate reaction) I notice that within days of eating a cluster of gluten, I start to feel really hypo.

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    Interesting...since I had Hashimoto's about the same time I started getting celiac problems, though it has taken me 20 years to get a diagnosis of celiac.

    I'm right there with you .....I have been going through this for 20 years also getting the run around and playing ring around the rosey. Finally a Dr. who diagnoses me in about 5 min and tell me I'm not crazy!!!

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    For years I have suffered with Hashimoto's and could not understand why I could not loose weight on the oroxine medication even though I exercise and am active. Do you think a Gluten free diet could help me as I am 59 years old?

    @Colleen

    Yes, going gluten-free can help you lose weight if you don't go for the gluten free cookies and such. With the diet, you will cut out fattening foods like pastries, pies, cakes, and most cheap Asian food as Soy Sauce has gluten and Asian restaurants tend to throw all products (gluten and non-gluten) on the same grill so that everything gets contaminated. The resulting diet is very healthy if you eat naturally gluten free (i.e. mostly lean meat, vegetables, and rice and potatoes for the starch). Most imitation and fake foods have gluten (like imitation crab meat), so the diet will force you away from that unhealthy food as well. If you have a gluten intolerance, any repairs this diet allows your body to make to your system will help you body return to a state where it can regulate its weight better.

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    My mother has had Hashimoto's for years. She is 85 and a few years ago started to have all sorts of gastro-intestinal problems. I convinced her to get rid of the gluten and she has been a great deal better.

    I also have had Hasimoto's for the last 16 years. I really cut down on the bread a few years ago and I have been much better. The day will come when I have to give it up entirely I fear but until then I eat stuff made with wheat flour very sparingly.

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    Guest Dianna

    Posted

    I'm reading a book called "Why do I have Thyroid symptoms if my thyroid tests are normal". It is saying most doctors treat Hashimoto's as a thyroid disease by replacing the hormones the autoimmune keeps depleting plus most don't bother testing for adrenal wipe out. It is explaining why they should be treating the autoimmune disease and not be treating it like a thyroid disease. Many times thyroid meds only are a temporary relief. I've also ordered "Stop the thyroid madness" book.

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    Guest Candace

    Posted

    Excellent info. I want to add that if your thryoid tests are within normal range, and you then go off gluten, you will most likely lose weight. At this point, your medication dosage may be too high for your reduced body mass. It's very important to be re-checking your thyroid hormones if you lose weight or change your diet as you could veer into hyperthyroidism, which is what happened to me along with all the messy symptoms. Stay on top of this, please.

    Great tip because I too went off gluten and dropped 10 pounds right away and suddenly started suffering symptoms of hyperthyroidism and it took me a while to realize what was going on. I just moved and need to find a new doctor, but currently I have stopped taking any thyroid medication and am functioning really well....any other time in my life I was not on medication for hypothyroidism, I would turn into a zombie with lots of aches, pains, and feeling depressed. I was on 120 mcg of synthroid before, now I'm on nothing and doing better than ever. I am going to be scheduling an appointment with a new doc soon though just to keep on top of things.

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    Although the evidence toward gluten and Hashimoto's is strong so is the evidence from excessive Bromine intake relative to iodine intake. What is interesting is Bromine is added to bread in many areas. People who go gluten free are probably also removing a key source of Bromine from their diets. Needless to say, but there is a lot to figure out.

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    This web-site is excellent! I have learned so much ! Cutting back and eliminating all gluten has really helped. I feel less brain-fog, wake-up rested and ready to go, and my abdomen feels great not at all burning and painful.

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    Rogue antibodies cause damage in both organs, a really helpful article!

    I also would like to know if anyone has developed a condition with symptoms such as angeoedema (sp). hives, rashes, swollen lymph nodes under arms. and inflammation under the skin. Even though I have gone off gluten these symptoms still occur.

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    Guest Danielle

    Posted

    I also would like to know if anyone has developed a condition with symptoms such as angeoedema (sp). hives, rashes, swollen lymph nodes under arms. and inflammation under the skin. Even though I have gone off gluten these symptoms still occur.

    tlee,

    Yes, I have also experienced red rashes, hives, swelling all along my jaw line, neck, chest/breast area, even my arms, under arms, and shoulders. I have been trying very hard to stay gluten free but, I am also having these reactions with certain foods that claim to be gluten free. I also experience at times, extreme intolerance to cold, and become extremely tired (as if I had been drugged) I can't stay awake no matter how hard I try to fight it (this happens usually a few days before "that time of the month"). I too have had a great deal of difficulty trying to lose weight. I am very very active, I go to the gym. I do cardio, fat burning and weight /strength training every other day for 2.5-3 hrs. I also walk the opposite days that I am not at the gym for 2.5-3 hrs. I do feel like a freak at times!! Some people don't understand how it feels or what a struggle it is to deal with this on a daily basis.

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    Joyce... as a child they called "nervous stomach"... at 30, "colitis"... at 50 "IRS"... at 70, now, I've discovered it is gluten intolerance. I cannot begin to tell how much pain and emotional hard ache this condition has caused. If you suspect you may have celiac disease, get help and understanding. It will cause much damage if untreated.

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    I'm 35, and I have had problems all my life with my stomach, cystic acne, small blisters on my hands and feet, migraines (last one made me faint), depression, memory loss, sleeping problems and pain all over!!! Goodness, the list goes on and on. I have been hospitalized for my stomach and no doctor could ever tell me what was wrong. All these years and 4 kids later, I find people like you who leave comments on pages like this... what a great help!!! In reading your posts, I think now I can go into a doctor's office and tell them what test I need, not ask them... thanks!

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    Hi, I have Hashimoto's and when I stopped eating gluten in all forms, the swelling in my thyroid went away. And if I eat any gluten, my thyroid swells.

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    Delta was the first to strike. As reported by the New York Times on January 19: “Effective March 1, Delta, the second largest US airline by passenger traffic, said it will require passengers seeking to fly with pets to present additional documents outlining the passenger’s need for the animal and proof of its training and vaccinations, 48 hours prior to the flight.… This comes in response to what the carrier said was a 150 percent increase in service and support animals — pets, often dogs, that accompany people with disabilities — carried onboard since 2015.… Delta said that it flies some 700 service animals a day. Among them, customers have attempted to fly with comfort turkeys, gliding possums, snakes, spiders, and other unusual pets.”
    Fresh from an unsavory incident with an “emotional support” peacock incident, United Airlines has followed Delta’s lead and set stricter rules for emotional support animals. United’s rules also took effect March 1, 2018.
    So, to the relief of many bewildered passengers and crew, no more comfort turkeys, geese, possums or other questionable pets will be flying on Delta or United without meeting the airlines' strict new requirements for service and emotional support animals.
    Source:
    cnbc.com

    admin
    WHAT IS CELIAC DISEASE?
    Celiac disease is an autoimmune condition that affects around 1% of the population. People with celiac disease suffer an autoimmune reaction when they consume wheat, rye or barley. The immune reaction is triggered by certain proteins in the wheat, rye, or barley, and, left untreated, causes damage to the small, finger-like structures, called villi, that line the gut. The damage occurs as shortening and villous flattening in the lamina propria and crypt regions of the intestines. The damage to these villi then leads to numerous other issues that commonly plague people with untreated celiac disease, including poor nutritional uptake, fatigue, and myriad other problems.
    Celiac disease mostly affects people of Northern European descent, but recent studies show that it also affects large numbers of people in Italy, China, Iran, India, and numerous other places thought to have few or no cases.
    Celiac disease is most often uncovered because people experience symptoms that lead them to get tests for antibodies to gluten. If these tests are positive, then the people usually get biopsy confirmation of their celiac disease. Once they adopt a gluten-free diet, they usually see gut healing, and major improvements in their symptoms. 
    CLASSIC CELIAC DISEASE SYMPTOMS
    Symptoms of celiac disease can range from the classic features, such as diarrhea, upset stomach, bloating, gas, weight loss, and malnutrition, among others.
    LESS OBVIOUS SYMPTOMS
    Celiac disease can often less obvious symptoms, such fatigue, vitamin and nutrient deficiencies, anemia, to name a few. Often, these symptoms are regarded as less obvious because they are not gastrointestinal in nature. You got that right, it is not uncommon for people with celiac disease to have few or no gastrointestinal symptoms. That makes spotting and connecting these seemingly unrelated and unclear celiac symptoms so important.
    NO SYMPTOMS
    Currently, most people diagnosed with celiac disease do not show symptoms, but are diagnosed on the basis of referral for elevated risk factors. 

    CELIAC DISEASE VS. GLUTEN INTOLERANCE
    Gluten intolerance is a generic term for people who have some sort of sensitivity to gluten. These people may or may not have celiac disease. Researchers generally agree that there is a condition called non-celiac gluten sensitivity. That term has largely replaced the term gluten-intolerance. What’s the difference between celiac disease and non-celiac gluten-sensitivity? 
    CELIAC DISEASE VS. NON-CELIAC GLUTEN SENSITIVITY (NCGS)
    Gluten triggers symptoms and immune reactions in people with celiac disease. Gluten can also trigger symptoms in some people with NCGS, but the similarities largely end there.

    There are four main differences between celiac disease and non-celiac gluten sensitivity:
    No Hereditary Link in NCGS
    Researchers know for certain that genetic heredity plays a major role in celiac disease. If a first-degree relative has celiac disease, then you have a statistically higher risk of carrying genetic markers DQ2 and/or DQ8, and of developing celiac disease yourself. NCGS is not known to be hereditary. Some research has shown certain genetic associations, such as some NCGS patients, but there is no proof that NCGS is hereditary. No Connection with Celiac-related Disorders
    Unlike celiac disease, NCGS is so far not associated with malabsorption, nutritional deficiencies, or a higher risk of autoimmune disorders or intestinal malignancies. No Immunological or Serological Markers
    People with celiac disease nearly always test positive for antibodies to gluten proteins. Researchers have, as yet, identified no such antobodies or serologic markers for NCGS. That means that, unlike with celiac disease, there are no telltale screening tests that can point to NCGS. Absence of Celiac Disease or Wheat Allergy
    Doctors diagnose NCGS only by excluding both celiac disease, an IgE-mediated allergy to wheat, and by the noting ongoing adverse symptoms associated with gluten consumption. WHAT ABOUT IRRITABLE BOWEL SYNDROME (IBS) AND IRRITABLE BOWEL DISEASE (IBD)?
    IBS and IBD are usually diagnosed in part by ruling out celiac disease. Many patients with irritable bowel syndrome are sensitive to gluten. Many experience celiac disease-like symptoms in reaction to wheat. However, patients with IBS generally show no gut damage, and do not test positive for antibodies to gliadin and other proteins as do people with celiac disease. Some IBS patients also suffer from NCGS.

    To add more confusion, many cases of IBS are, in fact, celiac disease in disguise.

    That said, people with IBS generally react to more than just wheat. People with NCGS generally react to wheat and not to other things, but that’s not always the case. Doctors generally try to rule out celiac disease before making a diagnosis of IBS or NCGS. 
    Crohn’s Disease and celiac disease share many common symptoms, though causes are different.  In Crohn’s disease, the immune system can cause disruption anywhere along the gastrointestinal tract, and a diagnosis of Crohn’s disease typically requires more diagnostic testing than does a celiac diagnosis.  
    Crohn’s treatment consists of changes to diet and possible surgery.  Up to 10% of Crohn's patients can have both of conditions, which suggests a genetic connection, and researchers continue to examine that connection.
    Is There a Connection Between Celiac Disease, Non-Celiac Gluten Sensitivity and Irritable Bowel Syndrome? Large Number of Irritable Bowel Syndrome Patients Sensitive To Gluten Some IBD Patients also Suffer from Non-Celiac Gluten Sensitivity Many Cases of IBS and Fibromyalgia Actually Celiac Disease in Disguise CELIAC DISEASE DIAGNOSIS
    Diagnosis of celiac disease can be difficult. 

    Perhaps because celiac disease presents clinically in such a variety of ways, proper diagnosis often takes years. A positive serological test for antibodies against tissue transglutaminase is considered a very strong diagnostic indicator, and a duodenal biopsy revealing villous atrophy is still considered by many to be the diagnostic gold standard. 
    But this idea is being questioned; some think the biopsy is unnecessary in the face of clear serological tests and obvious symptoms. Also, researchers are developing accurate and reliable ways to test for celiac disease even when patients are already avoiding wheat. In the past, patients needed to be consuming wheat to get an accurate test result. 
    Celiac disease can have numerous vague, or confusing symptoms that can make diagnosis difficult.  Celiac disease is commonly misdiagnosed by doctors. Read a Personal Story About Celiac Disease Diagnosis from the Founder of Celiac.com Currently, testing and biopsy still form the cornerstone of celiac diagnosis.
    TESTING
    There are several serologic (blood) tests available that screen for celiac disease antibodies, but the most commonly used is called a tTG-IgA test. If blood test results suggest celiac disease, your physician will recommend a biopsy of your small intestine to confirm the diagnosis.
    Testing is fairly simple and involves screening the patients blood for antigliadin (AGA) and endomysium antibodies (EmA), and/or doing a biopsy on the areas of the intestines mentioned above, which is still the standard for a formal diagnosis. Also, it is now possible to test people for celiac disease without making them concume wheat products.

    BIOPSY
    Until recently, biopsy confirmation of a positive gluten antibody test was the gold standard for celiac diagnosis. It still is, but things are changing fairly quickly. Children can now be accurately diagnosed for celiac disease without biopsy. Diagnosis based on level of TGA-IgA 10-fold or more the ULN, a positive result from the EMA tests in a second blood sample, and the presence of at least 1 symptom could avoid risks and costs of endoscopy for more than half the children with celiac disease worldwide.

    WHY A GLUTEN-FREE DIET?
    Currently the only effective, medically approved treatment for celiac disease is a strict gluten-free diet. Following a gluten-free diet relieves symptoms, promotes gut healing, and prevents nearly all celiac-related complications. 
    A gluten-free diet means avoiding all products that contain wheat, rye and barley, or any of their derivatives. This is a difficult task as there are many hidden sources of gluten found in the ingredients of many processed foods. Still, with effort, most people with celiac disease manage to make the transition. The vast majority of celiac disease patients who follow a gluten-free diet see symptom relief and experience gut healing within two years.
    For these reasons, a gluten-free diet remains the only effective, medically proven treatment for celiac disease.
    WHAT ABOUT ENZYMES, VACCINES, ETC.?
    There is currently no enzyme or vaccine that can replace a gluten-free diet for people with celiac disease.
    There are enzyme supplements currently available, such as AN-PEP, Latiglutetenase, GluteGuard, and KumaMax, which may help to mitigate accidental gluten ingestion by celiacs. KumaMax, has been shown to survive the stomach, and to break down gluten in the small intestine. Latiglutenase, formerly known as ALV003, is an enzyme therapy designed to be taken with meals. GluteGuard has been shown to significantly protect celiac patients from the serious symptoms they would normally experience after gluten ingestion. There are other enzymes, including those based on papaya enzymes.

    Additionally, there are many celiac disease drugs, enzymes, and therapies in various stages of development by pharmaceutical companies, including at least one vaccine that has received financial backing. At some point in the not too distant future there will likely be new treatments available for those who seek an alternative to a lifelong gluten-free diet. 

    For now though, there are no products on the market that can take the place of a gluten-free diet. Any enzyme or other treatment for celiac disease is intended to be used in conjunction with a gluten-free diet, not as a replacement.

    ASSOCIATED DISEASES
    The most common disorders associated with celiac disease are thyroid disease and Type 1 Diabetes, however, celiac disease is associated with many other conditions, including but not limited to the following autoimmune conditions:
    Type 1 Diabetes Mellitus: 2.4-16.4% Multiple Sclerosis (MS): 11% Hashimoto’s thyroiditis: 4-6% Autoimmune hepatitis: 6-15% Addison disease: 6% Arthritis: 1.5-7.5% Sjögren’s syndrome: 2-15% Idiopathic dilated cardiomyopathy: 5.7% IgA Nephropathy (Berger’s Disease): 3.6% Other celiac co-morditities include:
    Crohn’s Disease; Inflammatory Bowel Disease Chronic Pancreatitis Down Syndrome Irritable Bowel Syndrome (IBS) Lupus Multiple Sclerosis Primary Biliary Cirrhosis Primary Sclerosing Cholangitis Psoriasis Rheumatoid Arthritis Scleroderma Turner Syndrome Ulcerative Colitis; Inflammatory Bowel Disease Williams Syndrome Cancers:
    Non-Hodgkin lymphoma (intestinal and extra-intestinal, T- and B-cell types) Small intestinal adenocarcinoma Esophageal carcinoma Papillary thyroid cancer Melanoma CELIAC DISEASE REFERENCES:
    Celiac Disease Center, Columbia University
    Gluten Intolerance Group
    National Institutes of Health
    U.S. National Library of Medicine
    Mayo Clinic
    University of Chicago Celiac Disease Center

    Jefferson Adams
    Celiac.com 04/17/2018 - Could the holy grail of gluten-free food lie in special strains of wheat that lack “bad glutens” that trigger the celiac disease, but include the “good glutens” that make bread and other products chewy, spongey and delicious? Such products would include all of the good things about wheat, but none of the bad things that might trigger celiac disease.
    A team of researchers in Spain is creating strains of wheat that lack the “bad glutens” that trigger the autoimmune disorder celiac disease. The team, based at the Institute for Sustainable Agriculture in Cordoba, Spain, is making use of the new and highly effective CRISPR gene editing to eliminate the majority of the gliadins in wheat.
    Gliadins are the gluten proteins that trigger the majority of symptoms for people with celiac disease.
    As part of their efforts, the team has conducted a small study on 20 people with “gluten sensitivity.” That study showed that test subjects can tolerate bread made with this special wheat, says team member Francisco Barro. However, the team has yet to publish the results.
    Clearly, more comprehensive testing would be needed to determine if such a product is safely tolerated by people with celiac disease. Still, with these efforts, along with efforts to develop vaccines, enzymes, and other treatments making steady progress, we are living in exciting times for people with celiac disease.
    It is entirely conceivable that in the not-so-distant future we will see safe, viable treatments for celiac disease that do not require a strict gluten-free diet.
    Read more at Digitaltrends.com , and at Newscientist.com