Jump to content
  • Sign Up
  • Join Our Community!

    Get help in our celiac / gluten-free forum.

  • Jefferson Adams
    Jefferson Adams

    Celiac Disease Problems You Want to Avoid

    Reviewed and edited by a celiac disease expert.

    Celiac.com 06/05/2015 - For anyone with celiac disease, following a lifelong gluten-free diet has been shown to relieve symptoms, and in celiac patients it has been shown to normalize serologic markers of celiac disease, and to restore damaged intestinal villi.

    Photo: CC--MeridicanNot following a gluten-free diet, on the other hand, can result in serious complications associated with malabsorption.

    When celiac disease goes untreated, when people who have celiac disease refuse to follow a gluten-free diet, chronic gluten-related inflammation and damage impairs absorption of nutrients, and likely causes malabsorption of oral medications.

    Malabsorption resulting from damaged mucosa can lead to:

    1. Nutritional deficiencies of the fat-soluble vitamins A, D, E, and K, as well as the B vitamins, thereby diminishing the absorption of iron, calcium, and folic acid. Nutritional deficiencies can lead to:
    2. Iron-deficiency anemia refractory to oral iron supplementation, and potentially osteoporosis and osteopenia due to bone loss due to decreased calcium and vitamin D absorption. A combination of nutritional deficiencies and the damaging effects of systemwide chronic inflammation can cause:
    3. Reproductive abnormalities, such as delayed puberty, secondary amenorrhea, infertility, or decreased fertility. Adverse immune responses to gluten ingestion can trigger other common manifestations, such as:
    4. Dermatitis herpetiformis, a papulovesicular rash. Beyond that, problems can include:
    5. Fractures secondary to low bone mineral density. In some cases, untreated celiac disease can lead to intestinal malignancies such as:
    6. Intestinal T-cell lymphomas.
    7. Small-bowel adenocarcinoma.
    8. Esophageal cancer.
    9. B- and T-cell non-Hodgkin lymphomas.

    Rapid, proper diagnosis and effective treatment of celiac disease are crucial to preventing a cascade of related problems that can further impair diagnosis, and cause irreparable damage to patient health.


    Source:


    User Feedback

    Recommended Comments

    Guest Lorri Devlin, BSN, MS, RN

    Posted

    Kudos for spreading the word about the harmful effects of gluten for celiacs. My dad died of the disease before anyone realized gluten had caused a lifetime of illness. He was frail, had fungal infection in his lungs, depression, neuropathy, herpetic dermatiformis and failure to thrive. My sister and I were diagnosed in our 40's. By then I had vitamin D deficiency, had been hospitalized four times with perforated intestines, and had undergone a colectomy. Since being gluten-free, I'm completely healthy. As a registered nurse I now make sure to assess for food intolerance whenever I see a patient with rashes, asthma, or unexplained fatigue.

    Share this comment


    Link to comment
    Share on other sites


    Join the conversation

    You are posting as a guest. If you have an account, sign in now to post with your account.
    Note: Your post will require moderator approval before it will be visible.

    Guest
    Add a comment...

    ×   Pasted as rich text.   Paste as plain text instead

      Only 75 emoji are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.


  • About Me

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University, and has authored more than 2,000 articles on celiac disease. His coursework includes studies in science, scientific methodology, biology, anatomy, medicine, logic, and advanced research. He previously served as SF Health News Examiner for Examiner.com, and devised health and medical content for Sharecare.com. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of the book "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

×
×
  • Create New...