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    Scott Adams
    The Finnish Coeliac Society/Suomen Keliakialiitto ry
    Hammareninkatu 7
    SF-33100 Tampere,
    Finland
    Phone:+358 3 2541 300
    Fax:+358 3 2541 350
    E-mail: info@keliakialiitto.fi
    Internet: www.keliakialiitto.fi

    Hameenlinna
    Group: Hameen Keliakiayhdistys ry
    Contact: Pj. Jorma Taipalus
    Janiksenpoiku 32
    13600 Hameenlinna
    Tel: (03) 616 1232
    Siht. Erja Kangasvuori
    Liisanaro 3
    13210 Hameenlinna
    Tel: (03) 674 8979
    Imatra
    Group: Imatran Seudun Keliakiayhdistys ry
    Contact: Pj. Helena Hallikainen
    Pajarintie 95
    56730 Laikko
    Tel: (05) 75 765
    Siht. Eila Lintunen
    Irmankatu 3
    55120 Imatra
    Tel: (05) 4322 550
    Joensuu
    Group: Pohjois - Karjalan Keliakiayhdistys ry
    Contact: Pj. Erkki Vallius
    Penttilankatu 1 B 9
    80220 Joensuu
    Tel: (013) 137 905
    Siht. Mauno Koljonen
    Ylasatamakatu 30 A 2
    80100 Joensuu
    Tel: (013) 225 709
    Jyvaskyla
    Group: Keski-Suomen Keliakiayhdistys ry
    Contact: Pj. Pirjo Laine
    Hirvenkello 14
    40520 Jyvaskyla
    Tel: (014) 641 054
    Siht. Sinikka Vihne
    Lahdepolku 3
    40500 Jyvaskyla
    Tel: (014) 241 003
    Kajaani
    Group: Kainuun Keliakiayhdistys
    Contact: Pj. Tarja Korvinen
    Lansitie 15 E
    87150 Kajaani
    Tel: (08) 628 004
    Siht. Helvi Paivi
    Karjakatu 10
    88600 Sotkamo
    Tel: (08) 6662 141
    Kemi
    Group: Lansi-Pohjan Keliakiayhdistys ry
    Contact: Pj. Sanni Raisanen
    Hervantie 20
    94400 Keminmaa
    Tel: (016) 270 272
    Siht. Anne-Mari Keronen
    Haapalankatu 5 A 4
    94100 Kemi
    Kemijarvi
    Group: Koillis-Lapin Keliakiayhdistys ry
    Contact: Pj. Reino Kunnari
    Poylionkatu 7
    98100 Kemijarvi
    Tel: (016) 813 516
    Siht. Ritva Pajari
    Riskinniementie
    98400 Isokyla
    Tel: (016) 880 044
    Kokkola
    Group: Kokkolanseudun Keliakiayhdistys ry
    Contact: Pj. Mauno Sulkala
    Tyynikatu 3
    67100 Kokkola
    Tel: (06) 831 2915
    Siht. Carita Holmberg
    Pengerkuja 6
    67100 Kokkola
    Tel: (06) 831 1504
    Kouvola
    Group: Pohjois-Kymenlaakson Keliakiayhdistys ry
    Contact: Pj. Aulikki Volanen
    Valimontie 16
    45100 Kouvola
    Tel: (05) 3754 369
    Siht. Raija Hayha
    Alankotie 5
    45120 Kouvola
    Tel: (05) 3117 663
    Kuopio
    Group: Pohjois-Savon Keliakiayhdistys ry
    Contact: Pj. Veikko Jokela
    Suunnistajantie 1 A 23
    70200 Kuopio
    Tel: (017) 282 5166
    Siht. Sisko Hentunen
    Kielorannankatu 27
    70820 Kuopio
    Tel: (017) 363 2454
    Kuusamo
    Group: Koillismaan Keliakiayhdistys
    Contact: Pj. Tarja Virkkula
    Kaakkurilammentie 9
    93999 Kuusamo
    Tel: (08) 8681 154
    Siht. Sirpa Vaarala
    Oravantie 9 A 18
    93600 Kuusamo
    Tel: (08) 8514 903
    Lahti
    Group: Paijat-Hameen Keliakiayhdistys ry
    Contact: Pj. Jorma Ahonen
    Uotilankatu 85 B
    15840 Lahti
    Tel: (03) 7535 505
    Siht. Seija Saaski
    Kansakoulunkatu 14 B 5
    15700 Lahti
    Tel: (03) 7823 764
    Metsakyla
    Group: Etela-Kymen Keliakiayhdistys ry
    Contact: Pj. Eija Aaltonen
    Hirventie 7
    49210 Huutjarvi
    Tel: (05) 3431 021
    Siht. Ritva Anttila
    Aholankuja 69
    49540 Metsakyla
    Tel: (05) 3458 151
    Mikkeli
    Group: Mikkelin Seudun Keliakiayhdistys ry
    Contact: Pj. lsto Liukkonen
    Otavantie 10
    50670 Otava
    Tel: (015) 170 241
    Siht. Heli Pyrhonen
    Sannastinlaakso 6 B 14
    50100 Mikkeli
    Tel: (015) 177 606
    Oulu
    Group: Oulun Seudun Keliakiayhdistys ry
    Contact: Pj. Vuokko Paaso
    Manttaalitie 2 C 15
    90650 Oulu
    Tel: (08) 530 3702
    Siht. Raili Toivio
    Kirkkokatu 55 B 15
    90120 Oulu
    Tel: (08) 3113 110
    Porvoo
    Group: Suur-Helsingin Keliakiayhdistys ry
    Contact: Pj. Hanna Kuntonen
    Joukahaisentie 9 C 59
    06150 Porvoo
    Tel: (019) 669 241
    Siht. Joni Torpo
    Lyvkkiniemi 13
    02160 Espoo
    Tel: (09) 452 1437
    Raahe
    Group: Raahen Tienoon Keliaakikot ry
    Contact: Pj. Erkki Sivonen
    Peiponpoiku 2
    92130 Raahe
    Tel: (08) 221 987
    Siht. Riitta Silvennoinen
    Vilpunlaakso 48
    92130 Raahe
    Tel: (08) 220 787
    Rauma
    Group: Rauman Seudun Keliakiayhdistys ry
    Contact: Pj. Maija Mattila
    Paroalhonkatu 6
    26660 Rauma
    Tel: (02) 8251 083
    Siht. Raija Uusitorppa
    Vinkkelinkuja 30 1 C
    26660 Rauma
    Tel: (02) 8250 802
    Rovaniemi
    Group: Rovaniemen Seudun Keliakiayhdistys
    Contact: Pj. Jorma Lietsalmi
    Palkisentie 13 as 2
    96100 Rovaniemi
    Tel: (016) 346 152
    Siht. Ritva Macklin
    Perapuistikko 1-3 B 7
    96190 Rovaniemi
    Tel: (016) 395 767
    Seinajoki
    Group: Seinajoen Seudun Keliakiayhdistys ry
    Contact: Pj. Paula Alanen
    Jokitie 12
    61230 Luopa
    Tel: (06) 4533 368
    Siht. Marjo Kauppi
    Jyrkkakallionkatu 1
    60320 Seinajoki
    Tel: (06) 4144 871
    Tampere
    Group: Pirkanmaan Keliakiayhdistys ry
    Contact: Pj. Pekka Collin
    Pellervonkatu 9, huone 1011
    33540 Tampere
    Varapj. Paavo Leskinen
    Tel: (03) 3645 719
    Siht. Kirsi Makinen
    Tel: (03) 3481 424
    Turku
    Group: Turun Seudun Keliakiayhdistys ry
    Contact: Pj. Tarja Kemppi
    Alikuimantie 362
    21450 Tarvasjoki
    Tel: (02) 848 172
    Siht. Pirjo Vienonen
    Vastarakinkatu 1 A 32
    20610 Turku
    Tel: (02) 2443 380
    Vaasa
    Group: Vaasan Seudun Keliakiayhdistys ry - Vasanejdens Celiakiforening rf
    Contact: Pj. Leif Lili-Their
    Korsholmanpuistikko 16
    65100 Vaasa
    Tel: (06) 312 7505
    Siht. Birgitta Finne
    Suopursuntie 8
    65280 Vaasa
    Tel: (06) 321 3637
    Yliharma
    Group: Harman Seudun Keliakiayhdistys ry
    Contact: Pj. Erkki Kallio
    Keskirannantie 2
    62375 Yliharma
    Tel: (06) 484 6363
    Siht. Taimi Hakomaki
    Kangastie Kp2
    62375 Yliharma
    Tel: (06) 484 6446

  • Recent Articles

    Jefferson Adams
    Celiac.com 06/18/2018 - Celiac disease has been mainly associated with Caucasian populations in Northern Europe, and their descendants in other countries, but new scientific evidence is beginning to challenge that view. Still, the exact global prevalence of celiac disease remains unknown.  To get better data on that issue, a team of researchers recently conducted a comprehensive review and meta-analysis to get a reasonably accurate estimate the global prevalence of celiac disease. 
    The research team included P Singh, A Arora, TA Strand, DA Leffler, C Catassi, PH Green, CP Kelly, V Ahuja, and GK Makharia. They are variously affiliated with the Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Lady Hardinge Medical College, New Delhi, India; Innlandet Hospital Trust, Lillehammer, Norway; Centre for International Health, University of Bergen, Bergen, Norway; Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Gastroenterology Research and Development, Takeda Pharmaceuticals Inc, Cambridge, MA; Department of Pediatrics, Università Politecnica delle Marche, Ancona, Italy; Department of Medicine, Columbia University Medical Center, New York, New York; USA Celiac Disease Center, Columbia University Medical Center, New York, New York; and the Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
    For their review, the team searched Medline, PubMed, and EMBASE for the keywords ‘celiac disease,’ ‘celiac,’ ‘tissue transglutaminase antibody,’ ‘anti-endomysium antibody,’ ‘endomysial antibody,’ and ‘prevalence’ for studies published from January 1991 through March 2016. 
    The team cross-referenced each article with the words ‘Asia,’ ‘Europe,’ ‘Africa,’ ‘South America,’ ‘North America,’ and ‘Australia.’ They defined celiac diagnosis based on European Society of Pediatric Gastroenterology, Hepatology, and Nutrition guidelines. The team used 96 articles of 3,843 articles in their final analysis.
    Overall global prevalence of celiac disease was 1.4% in 275,818 individuals, based on positive blood tests for anti-tissue transglutaminase and/or anti-endomysial antibodies. The pooled global prevalence of biopsy-confirmed celiac disease was 0.7% in 138,792 individuals. That means that numerous people with celiac disease potentially remain undiagnosed.
    Rates of celiac disease were 0.4% in South America, 0.5% in Africa and North America, 0.6% in Asia, and 0.8% in Europe and Oceania; the prevalence was 0.6% in female vs 0.4% males. Celiac disease was significantly more common in children than adults.
    This systematic review and meta-analysis showed celiac disease to be reported worldwide. Blood test data shows celiac disease rate of 1.4%, while biopsy data shows 0.7%. The prevalence of celiac disease varies with sex, age, and location. 
    This review demonstrates a need for more comprehensive population-based studies of celiac disease in numerous countries.  The 1.4% rate indicates that there are 91.2 million people worldwide with celiac disease, and 3.9 million are in the U.S.A.
    Source:
    Clin Gastroenterol Hepatol. 2018 Jun;16(6):823-836.e2. doi: 10.1016/j.cgh.2017.06.037.

    Jefferson Adams
    Celiac.com 06/16/2018 - Summer is the time for chips and salsa. This fresh salsa recipe relies on cabbage, yes, cabbage, as a secret ingredient. The cabbage brings a delicious flavor and helps the salsa hold together nicely for scooping with your favorite chips. The result is a fresh, tasty salsa that goes great with guacamole.
    Ingredients:
    3 cups ripe fresh tomatoes, diced 1 cup shredded green cabbage ½ cup diced yellow onion ¼ cup chopped fresh cilantro 1 jalapeno, seeded 1 Serrano pepper, seeded 2 tablespoons lemon juice 2 tablespoons red wine vinegar 2 garlic cloves, minced salt to taste black pepper, to taste Directions:
    Purée all ingredients together in a blender.
    Cover and refrigerate for at least 1 hour. 
    Adjust seasoning with salt and pepper, as desired. 
    Serve is a bowl with tortilla chips and guacamole.

    Dr. Ron Hoggan, Ed.D.
    Celiac.com 06/15/2018 - There seems to be widespread agreement in the published medical research reports that stuttering is driven by abnormalities in the brain. Sometimes these are the result of brain injuries resulting from a stroke. Other types of brain injuries can also result in stuttering. Patients with Parkinson’s disease who were treated with stimulation of the subthalamic nucleus, an area of the brain that regulates some motor functions, experienced a return or worsening of stuttering that improved when the stimulation was turned off (1). Similarly, stroke has also been reported in association with acquired stuttering (2). While there are some reports of psychological mechanisms underlying stuttering, a majority of reports seem to favor altered brain morphology and/or function as the root of stuttering (3). Reports of structural differences between the brain hemispheres that are absent in those who do not stutter are also common (4). About 5% of children stutter, beginning sometime around age 3, during the phase of speech acquisition. However, about 75% of these cases resolve without intervention, before reaching their teens (5). Some cases of aphasia, a loss of speech production or understanding, have been reported in association with damage or changes to one or more of the language centers of the brain (6). Stuttering may sometimes arise from changes or damage to these same language centers (7). Thus, many stutterers have abnormalities in the same regions of the brain similar to those seen in aphasia.
    So how, you may ask, is all this related to gluten? As a starting point, one report from the medical literature identifies a patient who developed aphasia after admission for severe diarrhea. By the time celiac disease was diagnosed, he had completely lost his faculty of speech. However, his speech and normal bowel function gradually returned after beginning a gluten free diet (8). This finding was so controversial at the time of publication (1988) that the authors chose to remain anonymous. Nonetheless, it is a valuable clue that suggests gluten as a factor in compromised speech production. At about the same time (late 1980’s) reports of connections between untreated celiac disease and seizures/epilepsy were emerging in the medical literature (9).
    With the advent of the Internet a whole new field of anecdotal information was emerging, connecting a variety of neurological symptoms to celiac disease. While many medical practitioners and researchers were casting aspersions on these assertions, a select few chose to explore such claims using scientific research designs and methods. While connections between stuttering and gluten consumption seem to have been overlooked by the medical research community, there is a rich literature on the Internet that cries out for more structured investigation of this connection. Conversely, perhaps a publication bias of the peer review process excludes work that explores this connection.
    Whatever the reason that stuttering has not been reported in the medical literature in association with gluten ingestion, a number of personal disclosures and comments suggesting a connection between gluten and stuttering can be found on the Internet. Abid Hussain, in an article about food allergy and stuttering said: “The most common food allergy prevalent in stutterers is that of gluten which has been found to aggravate the stutter” (10). Similarly, Craig Forsythe posted an article that includes five cases of self-reporting individuals who believe that their stuttering is or was connected to gluten, one of whom also experiences stuttering from foods containing yeast (11). The same site contains one report of a stutterer who has had no relief despite following a gluten free diet for 20 years (11). Another stutterer, Jay88, reports the complete disappearance of her/his stammer on a gluten free diet (12). Doubtless there are many more such anecdotes to be found on the Internet* but we have to question them, exercising more skepticism than we might when reading similar claims in a peer reviewed scientific or medical journal.
    There are many reports in such journals connecting brain and neurological ailments with gluten, so it is not much of a stretch, on that basis alone, to suspect that stuttering may be a symptom of the gluten syndrome. Rodney Ford has even characterized celiac disease as an ailment that may begin through gluten-induced neurological damage (13) and Marios Hadjivassiliou and his group of neurologists and neurological investigators have devoted considerable time and effort to research that reveals gluten as an important factor in a majority of neurological diseases of unknown origin (14) which, as I have pointed out previously, includes most neurological ailments.
    My own experience with stuttering is limited. I stuttered as a child when I became nervous, upset, or self-conscious. Although I have been gluten free for many years, I haven’t noticed any impact on my inclination to stutter when upset. I don’t know if they are related, but I have also had challenges with speaking when distressed and I have noticed a substantial improvement in this area since removing gluten from my diet. Nonetheless, I have long wondered if there is a connection between gluten consumption and stuttering. Having done the research for this article, I would now encourage stutterers to try a gluten free diet for six months to see if it will reduce or eliminate their stutter. Meanwhile, I hope that some investigator out there will research this matter, publish her findings, and start the ball rolling toward getting some definitive answers to this question.
    Sources:
    1. Toft M, Dietrichs E. Aggravated stuttering following subthalamic deep brain stimulation in Parkinson’s disease--two cases. BMC Neurol. 2011 Apr 8;11:44.
    2. Tani T, Sakai Y. Stuttering after right cerebellar infarction: a case study. J Fluency Disord. 2010 Jun;35(2):141-5. Epub 2010 Mar 15.
    3. Lundgren K, Helm-Estabrooks N, Klein R. Stuttering Following Acquired Brain Damage: A Review of the Literature. J Neurolinguistics. 2010 Sep 1;23(5):447-454.
    4. Jäncke L, Hänggi J, Steinmetz H. Morphological brain differences between adult stutterers and non-stutterers. BMC Neurol. 2004 Dec 10;4(1):23.
    5. Kell CA, Neumann K, von Kriegstein K, Posenenske C, von Gudenberg AW, Euler H, Giraud AL. How the brain repairs stuttering. Brain. 2009 Oct;132(Pt 10):2747-60. Epub 2009 Aug 26.
    6. Galantucci S, Tartaglia MC, Wilson SM, Henry ML, Filippi M, Agosta F, Dronkers NF, Henry RG, Ogar JM, Miller BL, Gorno-Tempini ML. White matter damage in primary progressive aphasias: a diffusion tensor tractography study. Brain. 2011 Jun 11.
    7. Lundgren K, Helm-Estabrooks N, Klein R. Stuttering Following Acquired Brain Damage: A Review of the Literature. J Neurolinguistics. 2010 Sep 1;23(5):447-454.
    8. [No authors listed] Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 43-1988. A 52-year-old man with persistent watery diarrhea and aphasia. N Engl J Med. 1988 Oct 27;319(17):1139-48
    9. Molteni N, Bardella MT, Baldassarri AR, Bianchi PA. Celiac disease associated with epilepsy and intracranial calcifications: report of two patients. Am J Gastroenterol. 1988 Sep;83(9):992-4.
    10. http://ezinearticles.com/?Food-Allergy-and-Stuttering-Link&id=1235725 
    11. http://www.craig.copperleife.com/health/stuttering_allergies.htm 
    12. https://www.celiac.com/forums/topic/73362-any-help-is-appreciated/
    13. Ford RP. The gluten syndrome: a neurological disease. Med Hypotheses. 2009 Sep;73(3):438-40. Epub 2009 Apr 29.
    14. Hadjivassiliou M, Gibson A, Davies-Jones GA, Lobo AJ, Stephenson TJ, Milford-Ward A. Does cryptic gluten sensitivity play a part in neurological illness? Lancet. 1996 Feb 10;347(8998):369-71.

    Jefferson Adams
    Celiac.com 06/14/2018 - Refractory celiac disease type II (RCDII) is a rare complication of celiac disease that has high death rates. To diagnose RCDII, doctors identify a clonal population of phenotypically aberrant intraepithelial lymphocytes (IELs). 
    However, researchers really don’t have much data regarding the frequency and significance of clonal T cell receptor (TCR) gene rearrangements (TCR-GRs) in small bowel (SB) biopsies of patients without RCDII. Such data could provide useful comparison information for patients with RCDII, among other things.
    To that end, a research team recently set out to try to get some information about the frequency and importance of clonal T cell receptor (TCR) gene rearrangements (TCR-GRs) in small bowel (SB) biopsies of patients without RCDII. The research team included Shafinaz Hussein, Tatyana Gindin, Stephen M Lagana, Carolina Arguelles-Grande, Suneeta Krishnareddy, Bachir Alobeid, Suzanne K Lewis, Mahesh M Mansukhani, Peter H R Green, and Govind Bhagat.
    They are variously affiliated with the Department of Pathology and Cell Biology, and the Department of Medicine at the Celiac Disease Center, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA. Their team analyzed results of TCR-GR analyses performed on SB biopsies at our institution over a 3-year period, which were obtained from eight active celiac disease, 172 celiac disease on gluten-free diet, 33 RCDI, and three RCDII patients and 14 patients without celiac disease. 
    Clonal TCR-GRs are not infrequent in cases lacking features of RCDII, while PCPs are frequent in all disease phases. TCR-GR results should be assessed in conjunction with immunophenotypic, histological and clinical findings for appropriate diagnosis and classification of RCD.
    The team divided the TCR-GR patterns into clonal, polyclonal and prominent clonal peaks (PCPs), and correlated these patterns with clinical and pathological features. In all, they detected clonal TCR-GR products in biopsies from 67% of patients with RCDII, 17% of patients with RCDI and 6% of patients with gluten-free diet. They found PCPs in all disease phases, but saw no significant difference in the TCR-GR patterns between the non-RCDII disease categories (p=0.39). 
    They also noted a higher frequency of surface CD3(−) IELs in cases with clonal TCR-GR, but the PCP pattern showed no associations with any clinical or pathological feature. 
    Repeat biopsy showed that the clonal or PCP pattern persisted for up to 2 years with no evidence of RCDII. The study indicates that better understanding of clonal T cell receptor gene rearrangements may help researchers improve refractory celiac diagnosis. 
    Source:
    Journal of Clinical Pathologyhttp://dx.doi.org/10.1136/jclinpath-2018-205023

    Jefferson Adams
    Celiac.com 06/13/2018 - There have been numerous reports that olmesartan, aka Benicar, seems to trigger sprue‐like enteropathy in many patients, but so far, studies have produced mixed results, and there really hasn’t been a rigorous study of the issue. A team of researchers recently set out to assess whether olmesartan is associated with a higher rate of enteropathy compared with other angiotensin II receptor blockers (ARBs).
    The research team included Y.‐H. Dong; Y. Jin; TN Tsacogianis; M He; PH Hsieh; and JJ Gagne. They are variously affiliated with the Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School in Boston, MA, USA; the Faculty of Pharmacy, School of Pharmaceutical Science at National Yang‐Ming University in Taipei, Taiwan; and the Department of Hepato‐Gastroenterology, Chi Mei Medical Center in Tainan, Taiwan.
    To get solid data on the issue, the team conducted a cohort study among ARB initiators in 5 US claims databases covering numerous health insurers. They used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for enteropathy‐related outcomes, including celiac disease, malabsorption, concomitant diagnoses of diarrhea and weight loss, and non‐infectious enteropathy. In all, they found nearly two million eligible patients. 
    They then assessed those patients and compared the results for olmesartan initiators to initiators of other ARBs after propensity score (PS) matching. They found unadjusted incidence rates of 0.82, 1.41, 1.66 and 29.20 per 1,000 person‐years for celiac disease, malabsorption, concomitant diagnoses of diarrhea and weight loss, and non‐infectious enteropathy respectively. 
    After PS matching comparing olmesartan to other ARBs, hazard ratios were 1.21 (95% CI, 1.05‐1.40), 1.00 (95% CI, 0.88‐1.13), 1.22 (95% CI, 1.10‐1.36) and 1.04 (95% CI, 1.01‐1.07) for each outcome. Patients aged 65 years and older showed greater hazard ratios for celiac disease, as did patients receiving treatment for more than 1 year, and patients receiving higher cumulative olmesartan doses.
    This is the first comprehensive multi‐database study to document a higher rate of enteropathy in olmesartan initiators as compared to initiators of other ARBs, though absolute rates were low for both groups.
    Source:
    Alimentary Pharmacology & Therapeutics