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  • Jefferson Adams
    Jefferson Adams

    Connection Found between Celiac Disease and Hashimoto's Thyroiditis

    Reviewed and edited by a celiac disease expert.

    Celiac.com 04/23/2007 - The results of a recent Dutch study published in the World Journal of Gastroenterology have confirmed a connection between Hashimotos Thyroiditis and celiac disease.

    In the study, 104 individuals with Hashimotos Thyroiditis were tested for immunoglobulin A anti-transglutaminase (tTG) antibodies, IgA anti-endomysial antibodies (EMA) and HLA-DQ typing. Those who tested positive for any of the serological tests were given an intestinal biopsy.

    Sixteen patients (15%) showed positive celiac serology and five patients clear villous atrophy were diagnosed with celiac disease (4.8%; 95% CI 0.7-8.9). All five patients diagnosed with celiac disease, and 53 patients with Hashimotos thyroiditis (50%; 95% CI 43-62), showed the presence of HLA-DQ2 (and/or -DQ8).

    In a separate test within the study, 184 Individuals with known celiac disease were given a serological test for thyroglobulin and thyroid peroxidase Antibodies, after first being given thyroid biochemical, a thyroxine-free thyroid stimulating hormone.

    39 patients (21%) showed positive thyroid serology. According to thyroid biochemistry results, ten patients showed euthyroidism (5%; 95% CI 2-9), seven showed sub-clinical hypothyroidism (3.8%; 95% CI 1.8-7.6), and 22 patients showed overt hypothyroidism, Hashimotos thyroiditis (12%; 95% CI 8-16). Furthermore, four patients with celiac disease had Graves disease (2%; 95% CI 0.8-5) and one patient had post-partum thyroiditis.

    The study concludes that there is a clear association between Hashimotos thyroiditis and celiac disease. Accordingly, it is recommended that patients with Hashimotos thyroiditis be screened for celiac disease and that patients with known celiac be screened for Hashimotos thyroiditis.

    World Journal of Gastroenterology 2007; 13(10).

    health writer who lives in San Francisco and is a frequent author of articles for Celiac.com.

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    I'm reading a book called "Why do I have Thyroid symptoms if my thyroid tests are normal". It is saying most doctors treat Hashimoto's as a thyroid disease by replacing the hormones the autoimmune keeps depleting plus most don't bother testing for adrenal wipe out. It is explaining why they should be treating the autoimmune disease and not be treating it like a thyroid disease. Many times thyroid meds only are a temporary relief. I've also ordered "Stop the thyroid madness" book.

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    Excellent info. I want to add that if your thryoid tests are within normal range, and you then go off gluten, you will most likely lose weight. At this point, your medication dosage may be too high for your reduced body mass. It's very important to be re-checking your thyroid hormones if you lose weight or change your diet as you could veer into hyperthyroidism, which is what happened to me along with all the messy symptoms. Stay on top of this, please.

    Great tip because I too went off gluten and dropped 10 pounds right away and suddenly started suffering symptoms of hyperthyroidism and it took me a while to realize what was going on. I just moved and need to find a new doctor, but currently I have stopped taking any thyroid medication and am functioning really well....any other time in my life I was not on medication for hypothyroidism, I would turn into a zombie with lots of aches, pains, and feeling depressed. I was on 120 mcg of synthroid before, now I'm on nothing and doing better than ever. I am going to be scheduling an appointment with a new doc soon though just to keep on top of things.

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    Although the evidence toward gluten and Hashimoto's is strong so is the evidence from excessive Bromine intake relative to iodine intake. What is interesting is Bromine is added to bread in many areas. People who go gluten free are probably also removing a key source of Bromine from their diets. Needless to say, but there is a lot to figure out.

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    This web-site is excellent! I have learned so much ! Cutting back and eliminating all gluten has really helped. I feel less brain-fog, wake-up rested and ready to go, and my abdomen feels great not at all burning and painful.

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    Rogue antibodies cause damage in both organs, a really helpful article!

    I also would like to know if anyone has developed a condition with symptoms such as angeoedema (sp). hives, rashes, swollen lymph nodes under arms. and inflammation under the skin. Even though I have gone off gluten these symptoms still occur.

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    I also would like to know if anyone has developed a condition with symptoms such as angeoedema (sp). hives, rashes, swollen lymph nodes under arms. and inflammation under the skin. Even though I have gone off gluten these symptoms still occur.

    tlee,

    Yes, I have also experienced red rashes, hives, swelling all along my jaw line, neck, chest/breast area, even my arms, under arms, and shoulders. I have been trying very hard to stay gluten free but, I am also having these reactions with certain foods that claim to be gluten free. I also experience at times, extreme intolerance to cold, and become extremely tired (as if I had been drugged) I can't stay awake no matter how hard I try to fight it (this happens usually a few days before "that time of the month"). I too have had a great deal of difficulty trying to lose weight. I am very very active, I go to the gym. I do cardio, fat burning and weight /strength training every other day for 2.5-3 hrs. I also walk the opposite days that I am not at the gym for 2.5-3 hrs. I do feel like a freak at times!! Some people don't understand how it feels or what a struggle it is to deal with this on a daily basis.

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    Joyce... as a child they called "nervous stomach"... at 30, "colitis"... at 50 "IRS"... at 70, now, I've discovered it is gluten intolerance. I cannot begin to tell how much pain and emotional hard ache this condition has caused. If you suspect you may have celiac disease, get help and understanding. It will cause much damage if untreated.

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    I'm 35, and I have had problems all my life with my stomach, cystic acne, small blisters on my hands and feet, migraines (last one made me faint), depression, memory loss, sleeping problems and pain all over!!! Goodness, the list goes on and on. I have been hospitalized for my stomach and no doctor could ever tell me what was wrong. All these years and 4 kids later, I find people like you who leave comments on pages like this... what a great help!!! In reading your posts, I think now I can go into a doctor's office and tell them what test I need, not ask them... thanks!

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  • About Me

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University, and has authored more than 2,000 articles on celiac disease. His coursework includes studies in science, scientific methodology, biology, anatomy, medicine, logic, and advanced research. He previously served as SF Health News Examiner for Examiner.com, and devised health and medical content for Sharecare.com. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of the book "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

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  • Forum Discussions

    Thank you Ranchers Wife.  Since I'm asymptomatic, I would not know if I had gluten. I cannot imagine having to worry about getting sick from cross-contamination. 
    Hi Jenna1028, They test for DH by taking a small skin biopsy from clear skin next to a lesion.  If you have DH, you have celiac disease.  But, you need to be eating a gluten diet for 12 weeks (gluten challenge) before getting the skin bi...
    To the OP, once in a while this stuff happens.  Please feel free to start a new topic if that would make it easier.  I am afraid this is just part of forums on the internet. I hope this didn’t chase you off.  
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