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    Scott Adams

    Depressive Symptoms in Adult Celiac Disease

    Scott Adams
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    Reviewed and edited by a celiac disease expert.

    Celiac.com 11/24/2002 - The following is a Medline abstract on a study conducted by Italian researchers that demonstrated a connection between celiac disease and clinical depression.



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    Scand J Gastroenterol 1998 Mar;33(3):247-50 Related Articles, Links
    Ciacci C, Iavarone A, Mazzacca G, De Rosa A.
    Dept. of Gastroenterology, University of Naples Federico II, Italy.

    BACKGROUND: Psychic symptoms and depression have been reported in celiac disease (celiac disease). The aim of this study was to explore depression in a large cohort of adult celiac disease patients.

    METHODS: Depressive symptoms were evaluated in 92 adult celiacs, 100 normal controls (NC), and 48 chronic persistent hepatitis (CPH) patients by means of a modified version of the Zung Self-Rating Depression Scale (M-SDS). celiac disease patients were evaluated for the level of knowledge about celiac disease and the compliance with diet.

    RESULTS: The M-SDS score differentiated celiac disease patients from NC. Age at diagnosis and duration of and compliance with diet did not correlate with depression. Three main factors could be identified with the M-SDS: reactiveness, pessimism, and anhedonic-asthenic.

    CONCLUSION: Depressive symptoms are a feature of celiac disease; they are present to a similar extent in patients with childhood- and adulthood-diagnosed celiac disease. The results underline the relevance of personal psychological resources, which play a fundamental role in determining and sustaining depression.

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  • About Me

    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.


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