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    What is the difference between celiac disease and gluten intolerance?*


    Scott Adams


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    The following was posted by Kemp Randolph on the Celiac Listserv news group krand@pipeline.com:

    The difference is that between two immune related reactions, allergy and intolerance. I asked the question of the technical difference between the two some time ago and got no response. Its not based on overt symptoms, thats for sure. Were also not talking about the difference between latent celiac disease and overt weight-loss, apple belly celiac disease. You can be allergic and intolerant of the same substance or food In the case of milk, its lactose(milk carbohydrate) intolerance and milk protein allergy.

    My non-professional stab at the difference between intolerance and allergy then. Both can lead to intestinal damage. Theres a table in Marshs book showing that --page 155 , figure 6.13. Type 3 damage (flat destructive ) can occur from milk, soy, egg.... as well as celiac disease.

    The reaction to an intolerance seems to be that the substance is not digested. The immune part of the response involves only the circulating immunoglobins IgA, maybe IgG and related immune cells, receptors.

    The immune reaction to an allergy involves IgE. The substance may still be digested, but there may be allergic responses elsewhere outside the gut.

    Apple belly celiac disease is an intolerance. The problems elsewhere in the body, except for cancer, are related to nutritional deficiencies. The link to other autoimmune diseases is statistical genetics when two (or more) genes for each of two conditions are close together.

    For more information see the Allergy vs. Intolerance page.

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    Guest Freddie

    Posted

    I still don't know the difference between them--they say they are different but how are they?

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    Guest Marie Doherty

    Posted

    I do not understand either what the difference is between them!! Can someone clarify please

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    Guest L. Rensch

    Posted

    You need to do some more research. Celiacs, allergies and intolerance do not all damage the gut. Celiacs is the only one that damages the gut and does not allow nutritional absorption. Food allergies cause allergy type symptoms-skin rashes, itchy skin, and/or tummy problems. Intolerance bother the tummy, cause no damage, and go away once food has passed through.

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    Guest Laura Bachner

    Posted

    You need to do some more research. Celiacs, allergies and intolerance do not all damage the gut. Celiacs is the only one that damages the gut and does not allow nutritional absorption. Food allergies cause allergy type symptoms-skin rashes, itchy skin, and/or tummy problems. Intolerance bother the tummy, cause no damage, and go away once food has passed through.

    Um I hate to differ with you L. Rensch. I have gluten intolerance not celiac and I can officially tell you that as of now when I ingest gluten it takes 3 days for my tummy to be able to handle food well enough to feel normal again.

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    I just found out I'm. Allergic too!! It also takes about 3 days for my tummy to stop hurting!!

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    Guest Karen

    Posted

    Um I hate to differ with you L. Rensch. I have gluten intolerance not celiac and I can officially tell you that as of now when I ingest gluten it takes 3 days for my tummy to be able to handle food well enough to feel normal again.

    Isn't 3 days how long it typically takes your body to digest and expel food? Unless you have a particularly fast metabolism, it really is about getting the gluten out of your system whether your have an intolerance OR an allergy.

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    I have heard diverticulitis is the after effect of years of gluten intolerance.....

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    Sources:
    1. Toft M, Dietrichs E. Aggravated stuttering following subthalamic deep brain stimulation in Parkinson’s disease--two cases. BMC Neurol. 2011 Apr 8;11:44.
    2. Tani T, Sakai Y. Stuttering after right cerebellar infarction: a case study. J Fluency Disord. 2010 Jun;35(2):141-5. Epub 2010 Mar 15.
    3. Lundgren K, Helm-Estabrooks N, Klein R. Stuttering Following Acquired Brain Damage: A Review of the Literature. J Neurolinguistics. 2010 Sep 1;23(5):447-454.
    4. Jäncke L, Hänggi J, Steinmetz H. Morphological brain differences between adult stutterers and non-stutterers. BMC Neurol. 2004 Dec 10;4(1):23.
    5. Kell CA, Neumann K, von Kriegstein K, Posenenske C, von Gudenberg AW, Euler H, Giraud AL. How the brain repairs stuttering. Brain. 2009 Oct;132(Pt 10):2747-60. Epub 2009 Aug 26.
    6. Galantucci S, Tartaglia MC, Wilson SM, Henry ML, Filippi M, Agosta F, Dronkers NF, Henry RG, Ogar JM, Miller BL, Gorno-Tempini ML. White matter damage in primary progressive aphasias: a diffusion tensor tractography study. Brain. 2011 Jun 11.
    7. Lundgren K, Helm-Estabrooks N, Klein R. Stuttering Following Acquired Brain Damage: A Review of the Literature. J Neurolinguistics. 2010 Sep 1;23(5):447-454.
    8. [No authors listed] Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 43-1988. A 52-year-old man with persistent watery diarrhea and aphasia. N Engl J Med. 1988 Oct 27;319(17):1139-48
    9. Molteni N, Bardella MT, Baldassarri AR, Bianchi PA. Celiac disease associated with epilepsy and intracranial calcifications: report of two patients. Am J Gastroenterol. 1988 Sep;83(9):992-4.
    10. http://ezinearticles.com/?Food-Allergy-and-Stuttering-Link&id=1235725 
    11. http://www.craig.copperleife.com/health/stuttering_allergies.htm 
    12. https://www.celiac.com/forums/topic/73362-any-help-is-appreciated/
    13. Ford RP. The gluten syndrome: a neurological disease. Med Hypotheses. 2009 Sep;73(3):438-40. Epub 2009 Apr 29.
    14. Hadjivassiliou M, Gibson A, Davies-Jones GA, Lobo AJ, Stephenson TJ, Milford-Ward A. Does cryptic gluten sensitivity play a part in neurological illness? Lancet. 1996 Feb 10;347(8998):369-71.

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