Jump to content
  • Sign Up
Celiac.com Sponsor:

Celiac.com Sponsor:

  • Join Our Community!

    Get help in our celiac / gluten-free forum.

  • Jefferson Adams

    Gluten-free Diet Does Not Increase Cardiovascular Risk in Children with Celiac Disease

    Jefferson Adams

    Reviewed and edited by a celiac disease expert.

      In this study, children with celiac disease showed no increase in cardiovascular disease risk factors after one year on a strict gluten-free diet.

    Caption: Image: CC--PoYang_博仰

    Celiac.com 05/14/2019 - A strict gluten-free diet is the only proven treatment for celiac disease, yet researchers still don't know what effect, if any, the diet might have on risk factors for cardiovascular disease. 

    A team of researchers recently set out to determine whether following a gluten-free diet influences risk factors for cardiovascular disease among newly diagnosed pediatric celiac disease subjects. Their results suggest that a gluten-free diet does not increase cardiovascular disease risk, at least in the short-term.

    Celiac.com Sponsor:

    The research team included E Zifman, O Waisbourd-Zinman, L Marderfeld, N Zevit, A Guz-Mark, A Silbermintz, A Assa, Y Mozer-Glassberg, N Biran, D Reznik, I Poraz, and R Shamir. They are variously affiliated with the Institute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach-Tikva; Pediatric Gastroenterology Clinic, Pediatric Division, Meir Medical Center, Kfar-Saba; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; and the Clinical Nutrition and Dietetics Department, Schneider Children's Medical Center of Israel, Petach-Tikva.

    For their study, the team prospectively enrolled pediatric patients receiving upper gastrointestinal endoscopy for suspected celiac disease.  Team members recorded physical and lab data related to cardiovascular disease risk, both at celiac diagnosis and after 1 year following a gluten-free diet, and assessed any variation in risk fo cardiovascular disease. The team used both paired tests or Wilcoxon nonparametric tests, as needed.

    In this study, children with celiac disease showed no increase in cardiovascular disease risk factors after one year on a strict gluten-free diet. The results did show a small increase in median fasting insulin levels, but no increase in insulin resistance as measured by homeostatic model assessment. During the same period, rates of dyslipidemia remained steady, while median high-density lipoprotein levels increased. The long-term implications of these small changes is not clear.

    So, at least in the short run, it looks like a gluten-free diet doesn't increase risk for cardiovascular disease in children with celiac disease. Further study is needed to determine if that's true long-term.

    Read more at the Journal of Pediatric Gastroenterology & Nutrition; 2019 May;68(5):684-688.

    User Feedback

    Recommended Comments

    There are no comments to display.

    Join the conversation

    You are posting as a guest. If you have an account, sign in now to post with your account.
    Note: Your post will require moderator approval before it will be visible.

    Add a comment...

    ×   Pasted as rich text.   Paste as plain text instead

      Only 75 emoji are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.

  • About Me

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University, and has authored more than 2,500 articles on celiac disease. His coursework includes studies in science, scientific methodology, biology, anatomy, medicine, logic, and advanced research. He previously served as SF Health News Examiner for Examiner.com, and devised health and medical content for Sharecare.com. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of the book "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

  • Related Articles

    Jefferson Adams
    Celiac.com 07/10/2013 - Some doctors and nutritionists have expressed concern that a gluten-free diet might increase the risk of cardiovascular problems in patients with celiac disease.
    To get closer to an answer for this question, a team of researchers set out to assess changes of multiple cardiovascular risk factors in celiac patients evaluated before and during a gluten...

    Jefferson Adams
    Celiac.com 03/13/2015 - People who suffer from celiac disease with persistent villous atrophy do not face any higher risk of ischemic heart disease or atrial fibrillation, according to a recent study by a research team in Sweden.
    This is important, because patients with celiac disease do face an increased risk of death from cardiovascular causes, so it is mildly encouraging...

    Jefferson Adams
    Celiac.com 03/14/2016 - Compared with the general population, people with celiac disease are almost twice as likely to have coronary artery disease (CAD), and 1.4 times as likely to suffer a stroke, according to a large retrospective study presented at the American College of Cardiology (ACC) Scientific Sessions.
    The data indicate that people with celiac disease might be at...

    Jefferson Adams
    Celiac.com 10/05/2017 - Recent data show that more adults with celiac disease may face a higher risk for cardiovascular disease compared with the general population.
    A team of researchers recently set out to investigate the association of with cardiovascular disease risk factors at late adolescence in a cross-sectional population-based study.
    The research team included Assa...

  • Celiac.com Sponsor:

  • Forum Discussions

    Personallyu Well, actually there are plenty of studies showing the ingredients in GliadinX in fact does break down gluten by 50-85% before it reaches the small intestine. I believe the reason Scott recommends using it when you are ...
    I’ve been gluten free going on 14 years and as you all know accidents happen along the way especially when you are eating at someone else’s house or restaurants. ive been getting these attacks throughout the years and after having another one ...
    Have your doctors check for Mast Cell Activation Syndrome, which is still pretty new and not well known (not an IgE response, but similar in terms of symptoms).    It can be extreme or mild.   My triggers are insect bites and medications lik...
  • Create New...