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    Celiac.com Sponsor: Review

    How GliadinX Saved My Mom on Thanksgiving

    Reviewed and edited by a celiac disease expert.

    Caption: Image: CC--TheCulinaryGeek

    Celiac.com 12/09/2017 - For those of you who haven't yet heard about GliadinX, it is a dietary supplement with the highest concentration of AN-PEP, Prolyl Endopeptidase (Aspergillus Niger), and, unlike other enzymes, these have been shown in studies to break down gluten in the stomach.

    I've been using them regularly for months, and I tend to take them whenever I eat out, or eat at a friend's house, so basically whenever I don't have control over my food's preparation. Since I began doing this I haven't had any incidents of upset stomach, which are my typical symptoms if I get any cross contamination. However, it is hard to prove a negative...after all, perhaps I haven't had any issues because all of the food I ate was 100% gluten-free...right?

    I will now describe a recent glutening incident that involved none other than my Mother, who visited us this past Thanksgiving. How this could happen in my home, after all I'm the owner of Celiac.com, is an embarrassing but true story which I will share here in the hope that it will help you avoid my errors, and perhaps give you a way to recover should something similar ever happen.

    My brother brought over three pies for Thanksgiving dessert, one was a gluten-free apple pie, and the other two were pumpkin pies: one was gluten-free, but the other was not. What could go wrong, right? My brother's reasoning for bringing a non gluten-free pie into my house was pretty basic: several of the guests were not on a gluten-free diet, so he wanted to offer them what they were used to.

    What you need to know about my Mother is that she's very gluten sensitive. A tiny amount of gluten leaves her wrecked for days. I think you probably know where I'm going here, but basically everyone was busy socializing, eating, or cleaning while dessert was being served, and a friend grabbed a piece of the gluten-containing pumpkin pie (she assumed that if it was in MY house it was gluten-free) and handed it to my Mother. After she swallowed two bites we realized the mistake, but it was too late. My Mother had the look of horror on her face as she realized that the rest of her trip to California was probably ruined.

    I immediately flew into action and gave her several capsules of GliadinX, which she took with lots of water. We carried on with the evening, and I checked in with her over the next couple of hours. Amazingly she didn't have any noticeable symptoms or issues, but she was still certain that they were coming, and that she wouldn't get any sleep and would feel horrible the next day. Remarkably, none of her worries came true. She slept fine, and woke up feeling great. We were both amazed because any past similar incidents always ended badly for her.

    Suffice it to say that my Mother now keeps a bottle of GliadinX with her all the time...just in case!

    --by Scott Adams

    Many people have asked Celiac.com how they can order this product, so we've included a "Buy Now" link below to order them directly from the manufacturer:

    PayPal - The safer, easier way to pay online!

     

    Quote

     

    12. Treatment of the Extra-Intestinal Manifestations of CD

    ...the only one that is currently on the market is the gluten-specific enzyme, GliadinX (AN-PEP). Unfortunately, it is only capable of detoxifying 0.2 g of gluten or roughly that of 1/8 of a slice of gluten-containing bread. For this reason, it should only be used as an adjunct to the GFD when there are concerns for accidental gluten contamination and in an effort to ameliorate symptoms, not as a replacement for the GFD.

     

     

    Sources: Scientific publications on AN-PEP enzymes:


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    Hey Scott, you said your mother is highly sensitive/allergic to gluten. Are her reactions to contamination like violent vomiting, unable to move, unable to talk, etc., to the point that she would wind up in the ER,? I unfortunately had that happen to me 3 days before this past Christmas. Again! I ask this as I am so leary of anything that sounds too good to be true. I don't go out to eat anymore because of my truly severe reactions to gluten. Hope your Mom continues to be OK!

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    Hey Scott, you said your mother is highly sensitive/allergic to gluten. Are her reactions to contamination like violent vomiting, unable to move, unable to talk, etc., to the point that she would wind up in the ER,? I unfortunately had that happen to me 3 days before this past Christmas. Again! I ask this as I am so leary of anything that sounds too good to be true. I don't go out to eat anymore because of my truly severe reactions to gluten. Hope your Mom continues to be OK!

    Although she would not need to go to the emergency room (what could the ER do for you for gluten ingestion anyway? Just curious.), she would be unable to leave home for a few days, and would be feeling poorly for longer. If you never eat out and always prepare your own food, you probably don't need this (although there is still some risk, even with products marked "gluten-free.")

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    Interesting to see another product that works. I have been doing the same, taking enzymes whenever I have a meal out to ward off a cross contamination reaction, for close to 10 years. I have posted about it on the forums but people poo poo it. However when I go on vacation with my mom and give her the enzymes every meal and force her to order gluten free by the end of the week a disheveled, tired, confused person becomes sparkly, sharp dressing, and greeted me on the last day of the trip by doing deep knee bends. I used to use Gluten Ease but as I got older I switched to Digest Spectrum. Will have to look at trying this one also.

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    I am extremely sensitive to gluten. All my medications are guaranteed gluten-free, including OTC's. I recently gave up my beloved sesame seeds! There is never any cross-contamination in our kitchen. For six months I took large amounts of probiotics which were ordered online and cost way too much; they did nothing to help my symptoms. I don't get it; if GliadinX works so well then why can't we take it and eat what we want?!

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    I am extremely sensitive to gluten. All my medications are guaranteed gluten-free, including OTC's. I recently gave up my beloved sesame seeds! There is never any cross-contamination in our kitchen. For six months I took large amounts of probiotics which were ordered online and cost way too much; they did nothing to help my symptoms. I don't get it; if GliadinX works so well then why can't we take it and eat what we want?!

    This isn't a treatment for celiac disease, although it may be far better than nothing in cases where you may get some contamination.

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    9 hours ago, Guest Robert said:

    My most severe gluten symptoms don't appear until days later, then I'm really screwed. How do you know if the supplement worked long term?

    Might have to take it several times a day...I found it helps alleviate symptoms, last few gluten exposure taking it have preventing the violent vomiting, gut pain, and motor loss.....but I have still had minor D more of really soft  stools, numbness, and other quirks .....it really lessons symptoms in my experience. it is not a cure but does make accidentally glutening less traumatic. It is not a cure, or a miracle pill but it sure seems to help a bit.

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    I just had the genetic tests for celiac done on the 13th.  I have so many of the symptoms associated with this disorder, that I will be surprised if the test is negative.  The first profile of tests (gliadin, and others were negative, but thats because I stopped eating all gluten.  My gastro doc said it was a mistake to do that, so thats why got the script for the genetic tests.

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    At 64 this going gluten-free is not an easy undertaking, to say the least, but I lost 20 lbs in a three month period, and I wasn't trying to lose weight.  Even if the test comes back negative, I will never consume gluten again, it makes me feel that bad.

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    Now that my youngest daughter is on a GFD, she no longer has symptoms, but my oldest still has extreme sensitivity while on a GFD. I always wonder if my younger could be getting gluten and not know it. Although GliadinX helps the symptoms of eating gluten (and that is a daily issue for celiac disease patients), how does it handle the damage gluten does to the intestines?

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    1 hour ago, Guest Pamela said:

    Now that my youngest daughter is on a GFD, she no longer has symptoms, but my oldest still has extreme sensitivity while on a GFD. I always wonder if my younger could be getting gluten and not know it. Although GliadinX helps the symptoms of eating gluten (and that is a daily issue for celiac disease patients), how does it handle the damage gluten does to the intestines?

    Well it breaks done some of the gluten in the stomach before reaching the small intestines. It does not destroy all of it , is it depends on how much is eaten, stomach acidity, when the enzyme is taken, and the time it takes for your stomach to dump to the intestines.
    Basically it will not prevent all damage, it will help reduce it by reducing gluten content. The response and amount depends on the individuals immune system and above circumstances. This is more like a safety pill if you get some CC not for straight eating gluten.
    Best bet is a GFD and a gluten free household, whole foods, certified foods, and no eating out. But keep the glidenX for those odd random acts of life that lead to being CCed. It has helped with CCed gluten free labeled food that Nima found gluten in after I started feeling it, those times produce gets a flour dusting from the open air bakery (absurd but has happened) etc.

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