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    Is Triticum Monococcum (Einkorn) a Safe Wheat for those with Celiac Disease?


    Scott Adams

    Celiac.com 10/30/2006 - Triticum monococcum wheat is also known as Einkorn wheat and small spelt, but do not confuse it with common spelt which is not the same thing. Einkorn is the oldest and most primitive cultivated wheat, and recent studies have shown that it appears to lack gliadin toxicity and may be a safe wheat alternative for those with celiac disease. In the most recent study the researchers conclude that data show a lack of toxicity of triticum monococcum gliadin in an in vitro organ culture system, suggesting new dietary opportunities for celiac patients. If this is the case it appears that this grain is non-toxic to those with celiac disease.


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    Scand J Gastroenterol. 2006 Nov;41(11):1305-11.
    Lack of intestinal mucosal toxicity of Triticum monococcum in celiac
    disease patients.
    Pizzuti D, Buda A, DOdorico A, DInca R, Chiarelli S, Curioni A, Martines D.

    Abstract:

    Objective.
    The treatment of celiac disease is based on lifelong withdrawal of foods containing gluten. Unfortunately, compliance with a gluten-free diet has proved poor in many patients (mainly due to its low palatability), emphasizing the need for cereal varieties that are not toxic for celiac patients. In evolutionary terms, Triticum monococcum is the oldest and most primitive cultivated wheat. The aim of this study was to evaluate the toxicity of T. monococcum on small intestinal mucosa, using an in vitro organ culture system.

    Material and methods.
    Distal duodenum biopsies of 12 treated celiac patients and 17 control subjects were cultured for 24?h with T. aestivum (bread) gliadin (1?mg/ml) or with T. monococcum gliadin (1?mg/ml). Biopsies cultured with medium alone served as controls. Each biopsy was used for conventional histological examination and for immunohistochemical detection of CD3?+?intraepithelial lymphocytes (IELs) and HLA-DR. Secreted cytokine protein interferon-? (IFN–?) was measured in the culture supernatant using an enzyme-linked immunoadsorbent assay.

    Results.
    Significant morphological changes, HLA-DR overexpression in the crypt epithelium and an increased number of CD3?+?IELs, found after bread gliadin exposure, were not observed in celiac biopsies cultured with T. monococcum gliadin. In contrast, with bread gliadin, there was no significant IFN-? response after culture with monococcum gliadin. Similarly, biopsies from normal controls did not respond to bread or monococcum gliadin stimulation.

    Conclusions.
    These data show a lack of toxicity of T. monococcum gliadin in an in vitro organ culture system, suggesting new dietary opportunities for celiac patients.

    Note: Celiac.com strongly advises against celiacs including these grains in their diet until more testing and research is done to verify their safety.

    Einkorn Breadmaking Sites:

    Cereal Chem. 73 (2):208-214
    Breadmaking Quality of Einkorn Wheat (Triticum monococcum ssp. monococcum).
    http://www.aaccnet.org/cerealchemistry/backissues/1996/73_208.pdf

    Cereal Chem. 76 (5): Pub. no. C-1999-0804-01R
    Einkorn Characterization for Bread and Cookie Production in Relation to
    Protein Subunit Composition.
    http://www.aaccnet.org/cerealchemistry/abstracts/1999/0804-01r.asp


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    Guest Stan Ness

    Posted

    Einkorn has not yet been proven to be safe for celiacs. I've seen peer reviewed articles advocating both sides of that question. It may be safe for people with gluten or wheat “sensitivities†but celiac patients should be extremely cautious and consult a physician before trying einkorn. Also, there are hundreds of different types of einkorn, each with a unique set of gluten and gliadin proteins. With any luck, one will be found that everyone can eat safely.

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    Guest HALLU

    Posted

    There is only ONE "Triticum Monococcum", but since it's a landrace plant, it adapts extremely quickly to different environments and hence produces a great variety of different Einkorn grains, depending on your location and climate.

     

    Einkorn is as Safe of a grain as you will get, especially after re-stablishing a healthy intestinal flora after your modern-wheat onslaught !

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    Guest Annie Flanders

    Posted

    Einkorn has not yet been proven to be safe for celiacs. I've seen peer reviewed articles advocating both sides of that question. It may be safe for people with gluten or wheat “sensitivities†but celiac patients should be extremely cautious and consult a physician before trying einkorn. Also, there are hundreds of different types of einkorn, each with a unique set of gluten and gliadin proteins. With any luck, one will be found that everyone can eat safely.

    I would not touch einkorn with a 10 foot pole. I shall continue to eat wheat-free. Thank you Stan Ness for your insight.

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  • Related Articles

    Scott Adams
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    Jefferson Adams
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    Proceedings of the National Academy of Sciences

    Jefferson Adams
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    Source:
    Journal of Agricultural and Food Chemistry ACS News Service Weekly PressPac: April 3, 2013

    Jefferson Adams
    Ancient Wheat Strains Trigger Adverse Reactions in People with Celiac Disease
    Celiac.com 11/11/2014 - There have been claims that certain strains of wheat, especially ancient strains, such as einkorn, do not trigger adverse reactions in people with celiac disease, or that they trigger less severe reactions.
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    Source:
    Clin Nutr. 2013 Dec;32(6):1043-9. doi: 10.1016/j.clnu.2013.02.003

  • Recent Articles

    Alexander R. Shikhman, MD, PhD, FACR
    The Connection between Gluten Intolerance and Sjogren’s Syndrome
    Celiac.com 08/17/2018 - Mucosal dryness is among the top non-gastrointestinal complaints of patients with gluten intolerance and celiac disease.
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    If you’re concerned that dryness may represent Sjogren’s syndrome, see a rheumatologist for further evaluation and management of your condition.
    References:
    Alvarez-Celorio MD, Angeles-Angeles A, Kraus A. Primary Sjögren’s Syndrome and Celiac Disease: Causal Association or Serendipity? J Clin Rheumatol. 2000 Aug;6(4):194-7. Asrani AC, Lumsden AJ, Kumar R, Laurie GW. Gene cloning of BM180, a lacrimal gland enriched basement membrane protein with a role in stimulated secretion. Adv Exp Med Biol. 1998;438:49-54. Feuerstein J. Reversal of premature ovarian failure in a patient with Sjögren syndrome using an elimination diet protocol. J Altern Complement Med. 2010 Jul;16(7):807-9. Iltanen S, Collin P, Korpela M, Holm K, Partanen J, Polvi A, Mäki M. Celiac disease and markers of celiac disease latency in patients with primary Sjögren’s syndrome. Am J Gastroenterol. 1999 Apr;94(4):1042-6. Lemon S, Imbesi S., Shikhman A.R. Salivary gland imaging in Sjogren’s syndrome. Future Rheumatology, 2007 2(1):83-92. Roblin X, Helluwaert F, Bonaz B. Celiac disease must be evaluated in patients with Sjögren syndrome. Arch Intern Med. 2004 Nov 22;164(21):2387. Teppo AM, Maury CP. Antibodies to gliadin, gluten and reticulin glycoprotein in rheumatic diseases: elevated levels in Sjögren’s syndrome. Clin Exp Immunol. 1984 Jul;57(1):73-8.

    Jefferson Adams
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    Source:
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    Jefferson Adams
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    We at Celiac.com hope you and your family had a safe, enjoyable, and, yes, gluten-free Fourth of July. Stay tuned for more on gluten-free fireworks and other zany, tongue-in-cheek stories.
    Read more at kark.com
     

    Jefferson Adams
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    Celiac.com 08/13/2018 - It’s not uncommon for people to have psychiatric reactions to stressful life events, and these reactions may trigger some immune dysfunction. Researchers don’t yet know whether such reactions increase overall risk of autoimmune disease.
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    Source:
    JAMA. 2018;319(23):2388-2400. doi:10.1001/jama.2018.7028