Immune-mediated Inflammatory Diseases Common in Psoriasis Patients

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By Jefferson Adams

December 16, 2019
By Jefferson Adams • December 16, 2019

Immune-mediated Inflammatory Diseases Common in Psoriasis Patients

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Reviewed and edited by a celiac disease expert.

A team of researchers recently set out to investigate the chronology of immune-mediated inflammatory diseases relative to psoriasis.

Caption: Image: CC PDM 1.0-- l.aurenarmstrong

Celiac.com 12/16/2019 - Psoriasis is a skin condition associated with several immune-mediated inflammatory diseases, including celiac disease. Currently, however, researchers don't have much solid information regarding the chronology of psoriasis development.

A team of researchers recently set out to investigate the chronology of immune-mediated inflammatory diseases relative to psoriasis.

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The research team included Yuki M.F. Andersen, MD, PhD, Jashin J. Wu, MD, Jacob P. Thyssen, MD, PhD, DMS, and Alexander Egeberg, MD, PhD. They are variously affiliated with the Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark; the Dermatology Research and Education Foundation, Irvine, California; and the Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

The team reviewed data from Danish nationwide administrative registries to examine the occurrence of immune-mediated inflammatory diseases in 10,923 patients with psoriasis, and in 109,230 control subjects from the general population.

They found that about 20% of psoriasis patients developed one or more immune-mediated inflammatory diseases, with risk that is five times greater than in the general population.

Most patients received a diagnosis of immune-mediated inflammatory disease, except for psoriatic arthritis, before being diagnosed with psoriasis. Psoriasis patients were far more likely to have multiple immune-mediated inflammatory diseases. They were also far more likely to have human leukocyte antigen B27 positivity.

This study was limited by the unavailability of clinical measurements.

Still, the data show that immune-mediated inflammatory diseases are common in patients with psoriasis, and are usually diagnosed before psoriasis. This information could help researchers to better understand the factors influencing the development of psoriasis.

Read more in the Journal of the American Academy of Dermatology
autoimmune

celiac disease

comorbidity

epidemiology

imflammation

psoriasis
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Guest Gordon

Posted December 29, 2019

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Their is no doubt Psoriasis and celiac’s are Related I suffer from Psoriasis for years I was diagnosed with celiac‘s disease 10 years ago when I stopped eating wheat it went away and never came back. I think they a Hiding that fact from the public

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About Me

Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

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