Celiac.com 12/16/2019 - Psoriasis is a skin condition associated with several immune-mediated inflammatory diseases, including celiac disease. Currently, however, researchers don't have much solid information regarding the chronology of psoriasis development.
A team of researchers recently set out to investigate the chronology of immune-mediated inflammatory diseases relative to psoriasis.
The team reviewed data from Danish nationwide administrative registries to examine the occurrence of immune-mediated inflammatory diseases in 10,923 patients with psoriasis, and in 109,230 control subjects from the general population.
They found that about 20% of psoriasis patients developed one or more immune-mediated inflammatory diseases, with risk that is five times greater than in the general population.
Most patients received a diagnosis of immune-mediated inflammatory disease, except for psoriatic arthritis, before being diagnosed with psoriasis. Psoriasis patients were far more likely to have multiple immune-mediated inflammatory diseases. They were also far more likely to have human leukocyte antigen B27 positivity.
This study was limited by the unavailability of clinical measurements.
Still, the data show that immune-mediated inflammatory diseases are common in patients with psoriasis, and are usually diagnosed before psoriasis. This information could help researchers to better understand the factors influencing the development of psoriasis.
Read more in the Journal of the American Academy of Dermatology