Jump to content
  • Sign Up
Celiac.com Sponsor:

Celiac.com Sponsor:

  • Join Our Community!

    Get help in our celiac / gluten-free forum.

  • Jefferson Adams

    Irritable Bowel Syndrome and Non-celiac Gluten Sensitivity Have Much in Common

    Jefferson Adams

    Reviewed and edited by a celiac disease expert.

      Researchers Anupam Rej and David S. Sanders recently published a review exploring the complex relationship between the irritable bowel syndrome and non-celiac gluten sensitivity.

    Caption: Image: CC--Melissa Hillier

    Celiac.com 05/01/2019 - In the last decade, researchers have learned a great deal about gluten and celiac disease. More recently, there's been greater focus on non-celiac gluten-related disorders, especially the role of gluten in non-celiac gluten sensitivity (NCGS) and irritable bowel syndrome (IBS). 

    These conditions share some significant common connections. For example, a low FODMAP diet may help some people with both IBS, and NCGS. For many people the symptoms of IBS, and NCGS can be similar, making it hard to distinguish between the two conditions. Both IBS and NCGS can mimic celiac disease, though there are some key differences.

    Celiac.com Sponsor:

    Researchers Anupam Rej and David S. Sanders recently published a review exploring the complex relationship between the two disorders. They point out that recent data shows that gluten triggers symptoms in people with NCGS, and that gluten can trigger celiac-like symptom generation in patients with IBS. 

    Researchers are also increasingly looking at non-gluten components of wheat as possible triggers for symptoms in both conditions. Overall, there appears to be significant overlap between IBS and NCGS. 

    It is likely that a subset of patients presenting with IBS actually have NCGS. It's also likely that people with IBS have symptoms triggered by gluten. 

    Until researchers better understand both conditions, along with the role of wheat components in triggering symptoms, further research is required to help distinguish between both, and to delineate any connections between the two.

    Read more in Current Opinion in Gastroenterology 2019;35(3):199-205 (login required).

    User Feedback

    Recommended Comments

    Glad to hear they will look more into both IBS and NCGS and gluten tie in. I was misdiagnosed as IBS (by symptoms only ) for over twenty years. Gluten is very much my problem and sadly I ended up with additional tolerances too. I will never know if I had been diagnosed earlier if I would have only gluten issues and avoided the additional intolerances. I do hope others out there will be discovered earlier and on the road to recovery sooner than I.

    Share this comment

    Link to comment
    Share on other sites

    Join the conversation

    You are posting as a guest. If you have an account, sign in now to post with your account.
    Note: Your post will require moderator approval before it will be visible.

    Add a comment...

    ×   Pasted as rich text.   Paste as plain text instead

      Only 75 emoji are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.

  • About Me

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University, and has authored more than 2,500 articles on celiac disease. His coursework includes studies in science, scientific methodology, biology, anatomy, medicine, logic, and advanced research. He previously served as SF Health News Examiner for Examiner.com, and devised health and medical content for Sharecare.com. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of the book "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

  • Related Articles

    Jefferson Adams
    Celiac.com 06/06/2016 - Irritable Bowel Syndrome (IBS) is one of the most common types of functional bowel disorder. As researchers attempt to unravel the mysteries behind IBS, they have payed increasing attention to the possible impact of food and diet.
    For many people with IBS, certain foods seem to trigger or worsen symptoms, such as abdominal pain and bloating. Wheat is...

    Jefferson Adams
    Celiac.com 08/09/2016 - Some researchers have suggested that gluten may not be the actual trigger of symptoms in non-celiac gluten sensitivity. Others feel that gluten is definitely the trigger, especially in certain cases.
    A team of researchers recently set out to evaluate patients with clinical non-celiac gluten sensitivity (NCGS), who presented with lymphocytic enteritis...

    Jefferson Adams
    Celiac.com 12/15/2016 - Celiac disease and irritable bowel syndrome (IBS) can have similar symptoms, and confusion between the two can often cause delays in diagnosis. International guidelines recommend screening IBS patients for celiac disease using serological testing. However, studies published recently have cast doubt on the utility of this.
    A team of researchers recently...

    Jefferson Adams
    Celiac.com 11/20/2017 - People who do not have celiac disease, but who have celiac-like symptoms that improve on a gluten-free diet are prime candidates for a condition called non-celiac gluten sensitivity (NCGS).
    Researchers don't know much about the condition. There are no biomarkers, so they can't just do a blood test. People with this condition often experience celiac-like...

    Jefferson Adams
    Celiac.com 03/06/2019 - FODMAPs is an acronym, short for “fermentable, oligosaccharides, disaccharides, monosaccharides and polyols.” FODMAPs is a single name for a bunch of different molecules, common in many in foods, that are poorly absorbed by some people. People who can’t tolerate FODMAPs can suffer celiac-like gastrointestinal symptoms. A low FODMAP diet has been shown to hel...

  • Celiac.com Sponsor:

  • Forum Discussions

    Thank you very much. I will be getting the help from a natural doctor as I’m in the UK and Don’t find mainstream medicine very clued up about this kind of thing here. Thank you for your help XX
    Hi Kim! We can't tell just by what you posted. Every lab has different reference ranges so we would need those ranges. Can you please post those? Also, it doesn't matter if you have mild or severe intestinal symptoms as over 50% of diagnosed...
    Hello All, Just looking for information on vitamins. Had some testing come back this week that my bone density is low, as is my B12 and D. So, I clearly need to supplement, but have read that it's hard to trust vitamin brands that say...
  • Create New...