Jump to content
  • Sign Up
Celiac.com Sponsor:


Celiac.com Sponsor:


  • Join Our Community!

    Get help in our celiac / gluten-free forum.

  • Jefferson Adams

    Large Number of Irritable Bowel Syndrome Patients Sensitive to Gluten

    Jefferson Adams


    Reviewed and edited by a celiac disease expert.

    Caption: Photo: CC--Nana B. Agyei

    Celiac.com 07/29/2015 - Numerous studies have shown that a high percentage of patients with irritable bowel syndrome (IBS) are also sensitive to gluten. 

    A team of researchers recently set out to evaluate the effect of a gluten-free diet on gastrointestinal symptoms in patients with IBS. The research team included B. Shahbazkhani, A. Sadeghi, R. Malekzadeh, F. Khatavi, M. Etemadi, E. Kalantri, M. Rostami-Nejad, and K. Rostami.



    Celiac.com Sponsor:




    They are variously affiliated with the Gastroenterology Unit of Imam Khomeini Hospital at the Tehran University of Medical Sciences, Tehran, Iran, the Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran, the Sasan Alborz Biomedical Research Center, Masoud Gastroenterology and Hepatology Clinic, Tehran, Iran, the Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran, the Gholhak Medical Laboratory, Tehran, Iran, the Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, and with the Department of Gastroenterology, Alexandra Hospital, Worcestershire, UK.

    For their double-blind randomized, placebo-controlled trial, the team enrolled 148 IBS patients who fulfilled Rome III criteria between 2011 and 2013.

    Unfortunately, only 72 out of the 148 remained on a gluten-free diet for the six weeks needed to complete the study.

    The team recorded clinical symptoms biweekly using a standard visual analogue scale (VAS).

    In the second stage after six weeks, patients whose symptoms improved to an acceptable level were randomly divided into two groups; The first group of 35 patients received packages containing powdered gluten, while 37 patients received a gluten-free placebo powder.

    Nearly 84% of the gluten-free placebo group showed a significant improvement in symptoms compared to just under 26% for the gluten consuming group (p < 0.001).

    This study confirms that a large number of patients diagnosed with irritable bowel syndrome are sensitive to gluten.

    The team suggests that the term of IBS might be misleading and may change or delay an "effective and well-targeted treatment strategy in gluten sensitive patients."

    Source:


    User Feedback

    Recommended Comments

    Really? This is news? IBS is doctor's code for I Be Stumped, and I won't be digging any deeper to try to help you figure out the cause. Now take this hyoscyamine and deal.

    I'm an RN with celiac disease and have a son with celiac disease...any time I have a patient who has GI symptoms and autoimmune disease, I always insist on testing for celiac disease. And the funniest thing is that when I start to ask about family history, it almost always pops up that one family member has celiac or gluten intolerance but none of the extended family was ever tested. Still a huge lack of understanding and awareness in the medical community.

    Share this comment


    Link to comment
    Share on other sites
    Really? This is news? IBS is doctor's code for I Be Stumped, and I won't be digging any deeper to try to help you figure out the cause. Now take this hyoscyamine and deal.

    I'm an RN with celiac disease and have a son with celiac disease...any time I have a patient who has GI symptoms and autoimmune disease, I always insist on testing for celiac disease. And the funniest thing is that when I start to ask about family history, it almost always pops up that one family member has celiac or gluten intolerance but none of the extended family was ever tested. Still a huge lack of understanding and awareness in the medical community.

    I went gluten free after figuring it out for myself. I'm an RN as well. Refused to go back on gluten to have a test tell me what I already found out! Husband has had IBS his whole life. Got amazingly better on the gluten-free diet and suffered horribly when visiting relatives and ate what he wanted! Proof Positive... no further testing needed!!

    Share this comment


    Link to comment
    Share on other sites


    Join the conversation

    You are posting as a guest. If you have an account, sign in now to post with your account.
    Note: Your post will require moderator approval before it will be visible.

    Guest
    Add a comment...

    ×   Pasted as rich text.   Paste as plain text instead

      Only 75 emoji are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.


  • About Me

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University, and has authored more than 2,500 articles on celiac disease. His coursework includes studies in science, scientific methodology, biology, anatomy, medicine, logic, and advanced research. He previously served as SF Health News Examiner for Examiner.com, and devised health and medical content for Sharecare.com. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of the book "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

  • Related Articles

    Diana Gitig Ph.D.
    Celiac.com 05/18/2011 - Irritable Bowel Syndrome (IBS) is based on a clinical description only; there are no pathophysiological pathways definitively associated with it. It is characterized as gastrointestinal symptoms with no discernable cause. A diagnosis of IBS depends on recurrent abdominal pain or discomfort for at least three days per month in the last three months, with...

    Jefferson Adams
    Celiac.com 02/25/2013 - Patients with celiac disease often report symptoms compatible with irritable bowel syndrome (IBS). However, there haven't been any systematic studies regarding how adherence to a gluten-free diet might affect rates of irritable bowel syndrome-type symptoms in patients with celiac disease.
    To better answer that question, a research team conducted a meta...

    Jefferson Adams
    Celiac.com 12/30/2013 - Irritable bowel syndrome (IBS) and fibromyalgia syndrome (FMS) often occur together, and research indicates that many people with IBS plus FMS (IBS/FMS) might actually suffer from undiagnosed celiac disease.
    To better understand the potential connection between the two, a team of researchers recently conducted an active case finding for celiac disease...

    Jefferson Adams
    Celiac.com 06/04/2015 - Some researchers feel that people who self report non-celiac gluten sensitivity (SR-NCGS) and also follow a gluten-free diet might actually fall within the spectrum of irritable bowel (IBS). Interestingly, recent reports suggest that large numbers of people with inflammatory bowel disease (IBD) also follow a gluten-free diet.
    A research team recently...

  • Celiac.com Sponsor:

  • Forum Discussions

    Personallyu Well, actually there are plenty of studies showing the ingredients in GliadinX in fact does break down gluten by 50-85% before it reaches the small intestine. I believe the reason Scott recommends using it when you are ...
    I’ve been gluten free going on 14 years and as you all know accidents happen along the way especially when you are eating at someone else’s house or restaurants. ive been getting these attacks throughout the years and after having another one ...
    Have your doctors check for Mast Cell Activation Syndrome, which is still pretty new and not well known (not an IgE response, but similar in terms of symptoms).    It can be extreme or mild.   My triggers are insect bites and medications lik...
×
×
  • Create New...