• Join our community!

    Do you have questions about celiac disease or the gluten-free diet?

  • Ads by Google:
     




    Get email alerts Subscribe to Celiac.com's FREE weekly eNewsletter

    Ads by Google:



       Get email alertsSubscribe to Celiac.com's FREE weekly eNewsletter

  • Member Statistics

    71,934
    Total Members
    3,093
    Most Online
    kamafu
    Newest Member
    kamafu
    Joined
  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   04/07/2018

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes
  • 0

    DID GLUTEN REALLY PLAY A PART IN TOM BROKAW'S MULTIPLE MYELOMA?


    Jefferson Adams

    Celiac.com 05/29/2015 - On Thursday, May 7, Dateline featured Tom Brokaw's journey with multiple myeloma, a serious blood malignancy that develops in bone marrow.


    Ads by Google:




    ARTICLE CONTINUES BELOW ADS
    Ads by Google:



    Photo: Wikimedia CommonsNow an author of a recent book on gluten and health is saying that Brokaw's cancer may be linked to adverse gluten reactions.

    Numerous cancers, including non-Hodgkin's lymphoma, throat/esophageal, stomach/intestinal/colon, and multiple myeloma are now being connected to gluten consumption, says Anne Sarkisian, author of "Toxic Staple: How Gluten May Be Wrecking Your Health — And What You Can Do About It!!"Â

    Scientific research suggests that multiple myeloma may be linked to gluten, says Sarkisian, "and thousands of scientific studies from around the world link gluten to over 300 symptoms, diseases, and associated conditions."Â

    "Early detection of celiac disease is vital to reducing complications such as lymphoma and many other cancers and diseases. Does this mean a gluten-free lifestyle is preventative medicine? More alternative medical experts advocate this approach,"Â says Sarkisian.

    Could Brokaw's multiple myeloma be related to gluten? Possibly. Sarkisian's claim sounds good, and may be true, but, at the end of the day, there's just no way to know for sure.

    It is true that early detection of celiac disease is vital to reducing complications such as lymphoma and many other cancers and diseases, and it is also true, as Sarkisian asserts, that "More alternative medical experts advocate this approach [a gluten-free diet],"Â for many people without celiac disease. 

    Source:


    Image Caption: Tom Brokaw. Photo: Wikimedia Commons
    0


    User Feedback

    Recommended Comments

    Guest Christa

    Posted

    I am a blood and biopsy diagnosed celiac with refractory aprue and abnormal IEL's in my gut. My dad died of multiple myeloma, and his mother died from leukemia. However, the Army says that my dad's, and his mother's cancers occurred because my dad was in the atomic tests in Nevada in the 1950's. Celiac or radiation? That has been the question in my family.

    Share this comment


    Link to comment
    Share on other sites
    Guest frazer

    Posted

    The idea that celiac disease is separate from gluten intolerance is ludicrous. The continuum of reactions to gluten is vastly underplayed by the medical community as the answer is a gluten free diet, which leaves little for the script-writers to do. When from my personal experience of observing a clinical worker whose findings of over 60% of the population feeling better on a gluten free diet as represented by a food/mood diary where pulse and subjective interpretation of mood is considered over a course of six weeks, it is without question that people are better off without gluten in their diet. Whether a famous person is by cause and effect subject to cancer can not be determined ~ what is self-evident is that gluten as a late-comer to the human diet cannot be tolerated on a wide ranging basis as is currently the case.

    Share this comment


    Link to comment
    Share on other sites
    Guest Karen K.

    Posted

    I recently asked my GE, an expert in the field of celiac disease about the risk of lymphoma. I understood it to be around 11% risk, but he says that he believes it to be less than 4%. In his practice (a large team in a very large hospital system) there has not been a case yet determined. I don't worry about it.

    Share this comment


    Link to comment
    Share on other sites
    Guest Mary

    Posted

    I've been wondering about this for a long, long time.

     

    My Dad died of Multiple Myeloma and likely had undiagnosed celiac disease, as I was diagnosed six years after he died and my half sister was also diagnosed with celiac. His symptoms of celiac disease likely masked his illness because his diagnosis of multiple myeloma. His father (my grandfather) also died of a broken back, which according to my Uncle was likely also caused by multiple myeloma but was undiagnosed, so it cannot be confirmed. My uncle said their condition at the end was exactly the same.

     

     

    Share this comment


    Link to comment
    Share on other sites
    Guest Gluten KillsMe

    Posted

    This article is missing 2 very important statistics. According to the CDC, what is the rate of multiple myeloma within the general population? And, how does that compare with the rate of multiple myeloma among those with celiac diagnosis? A non-specific estimate made by just 1 doctor is hardly persuasive.

     

    My official diagnosis is gluten-sensitivity. This was made because I have all the worst symptoms of celiac disease whenever I ingest the tiniest bit of gluten and a blood test came back positive. Yet, after being back on a gluten-filled diet for 6 full weeks, a biopsy came back negative. Because of the negative biopsy, they cannot label it celiac disease. So, yes, gluten-sensitivity IS a genuine condition.

    Share this comment


    Link to comment
    Share on other sites
    Guest Anne Sarkisian author: Toxic Staple

    Posted

    Jeff thanks for responding. We'll never know for sure if gluten played a part in Tom Brokaw's multiple myeloma, however, there is some great research from Europe suggesting a strong link to gluten. Of course much more research is needed.

     

    I am trying to bring awareness to the myriad hazardous affects of gluten on the human body. Gluten can affect any part of the body and very little is being done to educate our medical professionals in all facets of medicine. Gluten is linked to cancers, autoimmune diseases, blood disorders, osteoporosis, anemia, skin and other organ issues, numerous neurological, cerebral, and muscular issues, and on and on.

     

    Unfortunately by the time a person is diagnosed with celiac disease they have quite compromised health and it has probably been brewing for years, maybe decades. It is important to recognize symptoms early before one's health becomes so degraded. Whether one has celiac disease or is gluten intolerant really doesn't matter according to more forward-thinking experts. If intolerant to gluten you need to abstain from it.

     

    Below is an endorsement from Professor Zorica Juranić:

     

    Reading the book Toxic Staple of Anne Sarkisian I was really amazed by her sincerity, and determination to confer the truth about so many toxic gluten effects. The book is perfectly written. No words to add or to remove from the text.

    Anne Sarkisian deserves the special respect for her book; firstly for her frankness, honesty, and courage to say the truth about her fight for the health of her loved ones, for the health of many gluten-sensitive people, the fight to open consciousness of health professionals for the complex, potentially harmful gluten effects.

    She alone, with her soul, heart and intellect, did great and hard job careffully searching through scientific medical literature. She clearly listed the clinical signs and laboratory tests related to diagnosis of gluten sensitivity (in almost all very serious health disorders connected with this) and not less important, she wrote about which food is healthy for people with proven gluten sensitivity. This points to Anne Sarkisian as the rare, unique, wise person, which with the book Toxic Staple, opens important new civilization breakthrough in the care of general people health.

    I warmly recommend this book for reading. It is a gift, full of knowledge which could help many people suffering from enormous reactivity to gluten to live healthier. Every information in this book is supported by appropriate reference from peer reviewed scientific journals that make it credible, not only for forward-thinking medical doctors, but also for all health professionals, as well as for non/educated people who are interested in their health and, more importantly, for the health of their loved ones.

     

    Zorica Juranić, PhD, Research Professor, Institute of Oncology and Radiology of Serbia

    Author of the publication: “Antibodies contained in "M" component of some patients with multiple myeloma are directed to food antigens?†Leuk Res. 2006 Dec; 30(12):1585-6.

     

     

    Share this comment


    Link to comment
    Share on other sites
    Guest Anne Sarkisian author: Toxic Staple

    Posted

    Jeff,

     

    A very belated thanks for editing and softening your original comment to the multiple myeloma/gluten article. Much appreciated.

     

    Best of health,

    Share this comment


    Link to comment
    Share on other sites


    Your content will need to be approved by a moderator

    Guest
    You are commenting as a guest. If you have an account, please sign in.
    Add a comment...

    ×   Pasted as rich text.   Paste as plain text instead

      Only 75 emoticons maximum are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.


  • Popular Contributors

  • Ads by Google:

  • Who's Online   11 Members, 0 Anonymous, 1,268 Guests (See full list)

  • Related Articles

    admin
    The other day I tried a bag of Crunchmaster Multi-seed Gluten-Free Crackers, which are a healthy oven-baked cracker, and I must say that they are an outstanding and very tasty gluten-free cracker.  In addition to being gluten-free they are also all natural, low sodium and cholesterol-free. 
    In addition to their great taste, what I really like about these crackers is the fact that they are made with whole grains and seeds, including brown rice meal, sesame seeds, quinoa seeds, flax seeds and amaranth seeds.  One serving size of 15 crackers packs a whopping 2 grams of dietary fiber and 280 mg of Omega-3, so these crackers are an excellent source of dietary fiber and Omega-3.
    I also really love the resealable bag that they come in, which helps to keep them fresh after you open them.
    Each cracker is shaped like a hexagon, which happens to be perfectly suited for adding your favorite toppings like cheese, dips, lunch meats or veggies.  I would recommend these crackers to anyone who is looking for a healthy, gluten-free snack, or as a healthy addition to your child’s school lunch.  They would also be a hit at any party or gathering, especially when combined with your favorite dips and toppings.
     
     
    Note: Articles that appearin the "Gluten-Free Product Reviews" section of this site are paid advertisements. For more information about this seeour Advertising Page.

    Dyani Barber
    I recently had the opportunity to try a gluten-free, sugar-free and starch-free cookie called "Cocoa-licious," which is manufactured by “Yes! To cookies.”  I have to be honest when I asked myself, “how good can a gluten, carb and sugar free cookie taste?”  When I opened the package, the smell of rich cocoa spilled out, and I discovered that each cookie was topped with a  type of glaze that made it appealing to the eye as well.  I no longer found myself hesitant to try these cookies, and now I'm glad that I did.  Each cookie was soft, moist and had a rich cocoa flavor. I did notice a slight aftertaste which I can only best describe as the same type of taste I get after I take a vitamin, but due to their uniqueness, I have to give these Cocoa-licious cookies a thumbs up.  I had no idea that there was such a thing as a sugar, carb and gluten-free cookie, but I can say that this cookie far exceeded my expectations.  It would be a great gluten-free snack for anyone who is watching their carbohydrate and sugar intake, and would satisfy a craving for something sweet.
    For more info visit their site: yestocookies.com
     
     
     

    Note:Articles that appearin the "Gluten-Free Product Reviews" section of this site are paidadvertisements. For more information about this seeour Advertising Page.


    Advertising Product-Review
    Premium Chocolatiers have struck a home run with their tasty Pea"not" Butter Cups.  These delightful treats look and taste just like traditional peanut butter cups with milk chocolate, but are peanut-free.  Crafted with a signature blend of roasted cocoa beans and cocoa butter with no shortenings or coatings added, these melt-in-your mouth candies are free of milk, nuts, gluten, and eggs. 
    They are perfect for anyone who loves the delicious combination of peanut butter and chocolate, but is on gluten-free diet or is allergic to peanuts.  Peanot Cups are especially great at Halloween or anytime. 
    For more information, visit their Web site.



    Review written by Patricia Seeley.

  • Recent Articles

    Jefferson Adams
    Celiac.com 04/20/2018 - A digital media company and a label data company are teaming up to help major manufacturers target, reach and convert their desired shoppers based on dietary needs, such as gluten-free diet. The deal could bring synergy in emerging markets such as the gluten-free and allergen-free markets, which represent major growth sectors in the global food industry. 
    Under the deal, personalized digital media company Catalina will be joining forces with Label Insight. Catalina uses consumer purchases data to target shoppers on a personal base, while Label Insight works with major companies like Kellogg, Betty Crocker, and Pepsi to provide insight on food label data to government, retailers, manufacturers and app developers.
    "Brands with very specific product benefits, gluten-free for example, require precise targeting to efficiently reach and convert their desired shoppers,” says Todd Morris, President of Catalina's Go-to-Market organization, adding that “Catalina offers the only purchase-based targeting solution with this capability.” 
    Label Insight’s clients include food and beverage giants such as Unilever, Ben & Jerry's, Lipton and Hellman’s. Label Insight technology has helped the Food and Drug Administration (FDA) build the sector’s very first scientifically accurate database of food ingredients, health attributes and claims.
    Morris says the joint partnership will allow Catalina to “enhance our dataset and further increase our ability to target shoppers who are currently buying - or have shown intent to buy - in these emerging categories,” including gluten-free, allergen-free, and other free-from foods.
    The deal will likely make for easier, more precise targeting of goods to consumers, and thus provide benefits for manufacturers and retailers looking to better serve their retail food customers, especially in specialty areas like gluten-free and allergen-free foods.
    Source:
    fdfworld.com

    Jefferson Adams
    Celiac.com 04/19/2018 - Previous genome and linkage studies indicate the existence of a new disease triggering mechanism that involves amino acid metabolism and nutrient sensing signaling pathways. In an effort to determine if amino acids might play a role in the development of celiac disease, a team of researchers recently set out to investigate if plasma amino acid levels differed among children with celiac disease compared with a control group.
     
    The research team included Åsa Torinsson Naluai, Ladan Saadat Vafa, Audur H. Gudjonsdottir, Henrik Arnell, Lars Browaldh, and Daniel Agardh. They are variously affiliated with the Institute of Biomedicine, Department of Microbiology & Immunology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; the Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; the Department of Pediatric Gastroenterology, Hepatology and Nutrition, Karolinska University Hospital and Division of Pediatrics, CLINTEC, Karolinska Institute, Stockholm, Sweden; the Department of Clinical Science and Education, Karolinska Institute, Sodersjukhuset, Stockholm, Sweden; the Department of Mathematical Sciences, Chalmers University of Technology, Gothenburg, Sweden; the Diabetes & Celiac Disease Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden; and with the Nathan S Kline Institute in the U.S.A.
    First, the team used liquid chromatography-tandem mass spectrometry (LC/MS) to analyze amino acid levels in fasting plasma samples from 141 children with celiac disease and 129 non-celiac disease controls. They then crafted a general linear model using age and experimental effects as covariates to compare amino acid levels between children with celiac disease and non-celiac control subjects.
    Compared with the control group, seven out of twenty-three children with celiac disease showed elevated levels of the the following amino acids: tryptophan; taurine; glutamic acid; proline; ornithine; alanine; and methionine.
    The significance of the individual amino acids do not survive multiple correction, however, multivariate analyses of the amino acid profile showed significantly altered amino acid levels in children with celiac disease overall and after correction for age, sex and experimental effects.
    This study shows that amino acids can influence inflammation and may play a role in the development of celiac disease.
    Source:
    PLoS One. 2018; 13(3): e0193764. doi: & 10.1371/journal.pone.0193764

    Jefferson Adams
    Celiac.com 04/18/2018 - To the relief of many bewildered passengers and crew, no more comfort turkeys, geese, possums or other questionable pets will be flying on Delta or United without meeting the airlines' strict new requirements for service animals.
    If you’ve flown anywhere lately, you may have seen them. People flying with their designated “emotional support” animals. We’re not talking genuine service animals, like seeing eye dogs, or hearing ear dogs, or even the Belgian Malinois that alerts its owner when there is gluten in food that may trigger her celiac disease.
    Now, to be honest, some of those animals in question do perform a genuine service for those who need emotional support dogs, like veterans with PTSD.
    However, many of these animals are not service animals at all. Many of these animals perform no actual service to their owners, and are nothing more than thinly disguised pets. Many lack proper training, and some have caused serious problems for the airlines and for other passengers.
    Now the major airlines are taking note and introducing stringent requirements for service animals.
    Delta was the first to strike. As reported by the New York Times on January 19: “Effective March 1, Delta, the second largest US airline by passenger traffic, said it will require passengers seeking to fly with pets to present additional documents outlining the passenger’s need for the animal and proof of its training and vaccinations, 48 hours prior to the flight.… This comes in response to what the carrier said was a 150 percent increase in service and support animals — pets, often dogs, that accompany people with disabilities — carried onboard since 2015.… Delta said that it flies some 700 service animals a day. Among them, customers have attempted to fly with comfort turkeys, gliding possums, snakes, spiders, and other unusual pets.”
    Fresh from an unsavory incident with an “emotional support” peacock incident, United Airlines has followed Delta’s lead and set stricter rules for emotional support animals. United’s rules also took effect March 1, 2018.
    So, to the relief of many bewildered passengers and crew, no more comfort turkeys, geese, possums or other questionable pets will be flying on Delta or United without meeting the airlines' strict new requirements for service and emotional support animals.
    Source:
    cnbc.com

    admin
    WHAT IS CELIAC DISEASE?
    Celiac disease is an autoimmune condition that affects around 1% of the population. People with celiac disease suffer an autoimmune reaction when they consume wheat, rye or barley. The immune reaction is triggered by certain proteins in the wheat, rye, or barley, and, left untreated, causes damage to the small, finger-like structures, called villi, that line the gut. The damage occurs as shortening and villous flattening in the lamina propria and crypt regions of the intestines. The damage to these villi then leads to numerous other issues that commonly plague people with untreated celiac disease, including poor nutritional uptake, fatigue, and myriad other problems.
    Celiac disease mostly affects people of Northern European descent, but recent studies show that it also affects large numbers of people in Italy, China, Iran, India, and numerous other places thought to have few or no cases.
    Celiac disease is most often uncovered because people experience symptoms that lead them to get tests for antibodies to gluten. If these tests are positive, then the people usually get biopsy confirmation of their celiac disease. Once they adopt a gluten-free diet, they usually see gut healing, and major improvements in their symptoms. 
    CLASSIC CELIAC DISEASE SYMPTOMS
    Symptoms of celiac disease can range from the classic features, such as diarrhea, upset stomach, bloating, gas, weight loss, and malnutrition, among others.
    LESS OBVIOUS SYMPTOMS
    Celiac disease can often less obvious symptoms, such fatigue, vitamin and nutrient deficiencies, anemia, to name a few. Often, these symptoms are regarded as less obvious because they are not gastrointestinal in nature. You got that right, it is not uncommon for people with celiac disease to have few or no gastrointestinal symptoms. That makes spotting and connecting these seemingly unrelated and unclear celiac symptoms so important.
    NO SYMPTOMS
    Currently, most people diagnosed with celiac disease do not show symptoms, but are diagnosed on the basis of referral for elevated risk factors. 

    CELIAC DISEASE VS. GLUTEN INTOLERANCE
    Gluten intolerance is a generic term for people who have some sort of sensitivity to gluten. These people may or may not have celiac disease. Researchers generally agree that there is a condition called non-celiac gluten sensitivity. That term has largely replaced the term gluten-intolerance. What’s the difference between celiac disease and non-celiac gluten-sensitivity? 
    CELIAC DISEASE VS. NON-CELIAC GLUTEN SENSITIVITY (NCGS)
    Gluten triggers symptoms and immune reactions in people with celiac disease. Gluten can also trigger symptoms in some people with NCGS, but the similarities largely end there.

    There are four main differences between celiac disease and non-celiac gluten sensitivity:
    No Hereditary Link in NCGS
    Researchers know for certain that genetic heredity plays a major role in celiac disease. If a first-degree relative has celiac disease, then you have a statistically higher risk of carrying genetic markers DQ2 and/or DQ8, and of developing celiac disease yourself. NCGS is not known to be hereditary. Some research has shown certain genetic associations, such as some NCGS patients, but there is no proof that NCGS is hereditary. No Connection with Celiac-related Disorders
    Unlike celiac disease, NCGS is so far not associated with malabsorption, nutritional deficiencies, or a higher risk of autoimmune disorders or intestinal malignancies. No Immunological or Serological Markers
    People with celiac disease nearly always test positive for antibodies to gluten proteins. Researchers have, as yet, identified no such antobodies or serologic markers for NCGS. That means that, unlike with celiac disease, there are no telltale screening tests that can point to NCGS. Absence of Celiac Disease or Wheat Allergy
    Doctors diagnose NCGS only by excluding both celiac disease, an IgE-mediated allergy to wheat, and by the noting ongoing adverse symptoms associated with gluten consumption. WHAT ABOUT IRRITABLE BOWEL SYNDROME (IBS) AND IRRITABLE BOWEL DISEASE (IBD)?
    IBS and IBD are usually diagnosed in part by ruling out celiac disease. Many patients with irritable bowel syndrome are sensitive to gluten. Many experience celiac disease-like symptoms in reaction to wheat. However, patients with IBS generally show no gut damage, and do not test positive for antibodies to gliadin and other proteins as do people with celiac disease. Some IBS patients also suffer from NCGS.

    To add more confusion, many cases of IBS are, in fact, celiac disease in disguise.

    That said, people with IBS generally react to more than just wheat. People with NCGS generally react to wheat and not to other things, but that’s not always the case. Doctors generally try to rule out celiac disease before making a diagnosis of IBS or NCGS. 
    Crohn’s Disease and celiac disease share many common symptoms, though causes are different.  In Crohn’s disease, the immune system can cause disruption anywhere along the gastrointestinal tract, and a diagnosis of Crohn’s disease typically requires more diagnostic testing than does a celiac diagnosis.  
    Crohn’s treatment consists of changes to diet and possible surgery.  Up to 10% of Crohn's patients can have both of conditions, which suggests a genetic connection, and researchers continue to examine that connection.
    Is There a Connection Between Celiac Disease, Non-Celiac Gluten Sensitivity and Irritable Bowel Syndrome? Large Number of Irritable Bowel Syndrome Patients Sensitive To Gluten Some IBD Patients also Suffer from Non-Celiac Gluten Sensitivity Many Cases of IBS and Fibromyalgia Actually Celiac Disease in Disguise CELIAC DISEASE DIAGNOSIS
    Diagnosis of celiac disease can be difficult. 

    Perhaps because celiac disease presents clinically in such a variety of ways, proper diagnosis often takes years. A positive serological test for antibodies against tissue transglutaminase is considered a very strong diagnostic indicator, and a duodenal biopsy revealing villous atrophy is still considered by many to be the diagnostic gold standard. 
    But this idea is being questioned; some think the biopsy is unnecessary in the face of clear serological tests and obvious symptoms. Also, researchers are developing accurate and reliable ways to test for celiac disease even when patients are already avoiding wheat. In the past, patients needed to be consuming wheat to get an accurate test result. 
    Celiac disease can have numerous vague, or confusing symptoms that can make diagnosis difficult.  Celiac disease is commonly misdiagnosed by doctors. Read a Personal Story About Celiac Disease Diagnosis from the Founder of Celiac.com Currently, testing and biopsy still form the cornerstone of celiac diagnosis.
    TESTING
    There are several serologic (blood) tests available that screen for celiac disease antibodies, but the most commonly used is called a tTG-IgA test. If blood test results suggest celiac disease, your physician will recommend a biopsy of your small intestine to confirm the diagnosis.
    Testing is fairly simple and involves screening the patients blood for antigliadin (AGA) and endomysium antibodies (EmA), and/or doing a biopsy on the areas of the intestines mentioned above, which is still the standard for a formal diagnosis. Also, it is now possible to test people for celiac disease without making them concume wheat products.

    BIOPSY
    Until recently, biopsy confirmation of a positive gluten antibody test was the gold standard for celiac diagnosis. It still is, but things are changing fairly quickly. Children can now be accurately diagnosed for celiac disease without biopsy. Diagnosis based on level of TGA-IgA 10-fold or more the ULN, a positive result from the EMA tests in a second blood sample, and the presence of at least 1 symptom could avoid risks and costs of endoscopy for more than half the children with celiac disease worldwide.

    WHY A GLUTEN-FREE DIET?
    Currently the only effective, medically approved treatment for celiac disease is a strict gluten-free diet. Following a gluten-free diet relieves symptoms, promotes gut healing, and prevents nearly all celiac-related complications. 
    A gluten-free diet means avoiding all products that contain wheat, rye and barley, or any of their derivatives. This is a difficult task as there are many hidden sources of gluten found in the ingredients of many processed foods. Still, with effort, most people with celiac disease manage to make the transition. The vast majority of celiac disease patients who follow a gluten-free diet see symptom relief and experience gut healing within two years.
    For these reasons, a gluten-free diet remains the only effective, medically proven treatment for celiac disease.
    WHAT ABOUT ENZYMES, VACCINES, ETC.?
    There is currently no enzyme or vaccine that can replace a gluten-free diet for people with celiac disease.
    There are enzyme supplements currently available, such as AN-PEP, Latiglutetenase, GluteGuard, and KumaMax, which may help to mitigate accidental gluten ingestion by celiacs. KumaMax, has been shown to survive the stomach, and to break down gluten in the small intestine. Latiglutenase, formerly known as ALV003, is an enzyme therapy designed to be taken with meals. GluteGuard has been shown to significantly protect celiac patients from the serious symptoms they would normally experience after gluten ingestion. There are other enzymes, including those based on papaya enzymes.

    Additionally, there are many celiac disease drugs, enzymes, and therapies in various stages of development by pharmaceutical companies, including at least one vaccine that has received financial backing. At some point in the not too distant future there will likely be new treatments available for those who seek an alternative to a lifelong gluten-free diet. 

    For now though, there are no products on the market that can take the place of a gluten-free diet. Any enzyme or other treatment for celiac disease is intended to be used in conjunction with a gluten-free diet, not as a replacement.

    ASSOCIATED DISEASES
    The most common disorders associated with celiac disease are thyroid disease and Type 1 Diabetes, however, celiac disease is associated with many other conditions, including but not limited to the following autoimmune conditions:
    Type 1 Diabetes Mellitus: 2.4-16.4% Multiple Sclerosis (MS): 11% Hashimoto’s thyroiditis: 4-6% Autoimmune hepatitis: 6-15% Addison disease: 6% Arthritis: 1.5-7.5% Sjögren’s syndrome: 2-15% Idiopathic dilated cardiomyopathy: 5.7% IgA Nephropathy (Berger’s Disease): 3.6% Other celiac co-morditities include:
    Crohn’s Disease; Inflammatory Bowel Disease Chronic Pancreatitis Down Syndrome Irritable Bowel Syndrome (IBS) Lupus Multiple Sclerosis Primary Biliary Cirrhosis Primary Sclerosing Cholangitis Psoriasis Rheumatoid Arthritis Scleroderma Turner Syndrome Ulcerative Colitis; Inflammatory Bowel Disease Williams Syndrome Cancers:
    Non-Hodgkin lymphoma (intestinal and extra-intestinal, T- and B-cell types) Small intestinal adenocarcinoma Esophageal carcinoma Papillary thyroid cancer Melanoma CELIAC DISEASE REFERENCES:
    Celiac Disease Center, Columbia University
    Gluten Intolerance Group
    National Institutes of Health
    U.S. National Library of Medicine
    Mayo Clinic
    University of Chicago Celiac Disease Center

    Jefferson Adams
    Celiac.com 04/17/2018 - Could the holy grail of gluten-free food lie in special strains of wheat that lack “bad glutens” that trigger the celiac disease, but include the “good glutens” that make bread and other products chewy, spongey and delicious? Such products would include all of the good things about wheat, but none of the bad things that might trigger celiac disease.
    A team of researchers in Spain is creating strains of wheat that lack the “bad glutens” that trigger the autoimmune disorder celiac disease. The team, based at the Institute for Sustainable Agriculture in Cordoba, Spain, is making use of the new and highly effective CRISPR gene editing to eliminate the majority of the gliadins in wheat.
    Gliadins are the gluten proteins that trigger the majority of symptoms for people with celiac disease.
    As part of their efforts, the team has conducted a small study on 20 people with “gluten sensitivity.” That study showed that test subjects can tolerate bread made with this special wheat, says team member Francisco Barro. However, the team has yet to publish the results.
    Clearly, more comprehensive testing would be needed to determine if such a product is safely tolerated by people with celiac disease. Still, with these efforts, along with efforts to develop vaccines, enzymes, and other treatments making steady progress, we are living in exciting times for people with celiac disease.
    It is entirely conceivable that in the not-so-distant future we will see safe, viable treatments for celiac disease that do not require a strict gluten-free diet.
    Read more at Digitaltrends.com , and at Newscientist.com