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      Frequently Asked Questions About Celiac Disease   04/07/2018

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes
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    MEDICAL TOURISM EXPANDS TO STEM CELL TREATMENTS


    Jefferson Adams

    Celiac.com 07/05/2012 - As more people seek out affordable medical services in foreign countries, the variety of available medical services continues to grow. Stem cells are just the latest in the list of medical services being targeted at foreign visitors.


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    Photo: CC--caribbA company called MediCAREtourism, a division of an Oman-based travel and hospitality company called Travel Point LLC, is introducing medical packages, including, stem cell treatments, to foreign travelers visiting destinations in Asia and the far east (Korea, Malaysia, and Singapore).

    Stem cell treatments are a type of intervention strategy that introduces new cells into damaged tissue in order to treat disease or injury. Many medical researchers believe that stem cell treatments have the potential to change the face of human disease with minimal risk of rejection and side effects.

    Medical researchers anticipate that adult and embryonic stem cells will soon be able to treat cancer, Type 1 diabetes mellitus, Parkinson's disease, Huntington's disease, Celiac Disease, cardiac failure, muscle damage and neurological disorders, liver cirrhosis and most importantly spinal injuries/paralytic cases from road accidents.

    Stem cell treatment is one of the fastest growing medical medical services in the world today, and provides many people with tremendous benefits, says Mr. Aslam Sayed Mohamed, Manager for MediCAREtourism, said.

    Travel Point is teaming up with Ming Medical Services of Malaysia to offer the stem cell packages, along with free medical consultation and general health checkups for all of their passengers traveling to Thailand & Malaysia.

    The health checkups will be held at accredited hospitals like Paulo Memorial Hospital in Bangkok (Thailand), Prince Court Medical Centre in Kuala Lumpur (Malaysia) and Sime Darby Medical Centre Ara Damansara in Selangor (Malaysia).

    This means that, in addition to free medical consultation, and general health checks, Travel Point customers traveling in Asia and the Far East can choose very affordable stem cell therapy packages to Malaysia and Thailand.

    Commenting on the importance of these treatment options, Dr. Sean NG, Managing Director, Ming Medical Services says stem cell treatments can give "100% cure to ailments like Vitiligo, Aging, Diabetes, Diabetic Ulcers, Autism, Cosmetic Abnormalities and end stage heart diseases."

    In a related story for the HuffingtonPost, Anthonia Akitunde notes that what was once regarded as an option only for the rich, medical tourism is becoming more and more popular among regular people. She cites estimates by Patients Beyond Borders, which produces guidebooks on medical travel, that in 2012, 600,000 people traveled abroad for treatment -- a number anticipated to grow 15 to 20 percent annually as boomers age.

    Source:


    Image Caption: Photo: CC--caribb
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    Dr. Ron Hoggan, Ed.D.
    The following is a post from Ron Hoggan - Q: I asked the doctor what an inflamed mucosa could mean and he shrugged and then added parasites, maybe? She was tested for parasites way back before her first biopsy (October 96).
    A: Have you tried eliminating dairy? Volta et. al. have demonstrated that 36% to 48% of celiacs tested were also intolerant to milk protein. Borner et. al. have demonstrated sequence homology, from the N-terminal, between casein and gliadin. The other three cited below are also identifying milk protein intolerances associated with celiac disease.
    Playing the odds, exclusion of dairy is most likely to help. But there are other significant dietary allergens that might be eliminated if a dairy free diet, in addition to the Gluten-free diet, doesnt help.
    Borner H, Isolation of antigens recognized by coeliac disease auto-antibodies and their use in enzyme immunoassay of endomysium and reticulin antibody-positive human sera. Clin Exp Immunol 106(2), 344-350 (1996)
    Hvatum M, Serum IgG subclass antibodies to a variety of food antigens in patients with coeliac disease. Gut 33(5), 632-638 (1992)
    Ciclitira PJ, Gliadin antibody production by small intestinal lymphocytes from patients with coeliac disease.Int Arch Allergy Appl Immunol 89(2-3), 246-249 (1989)
    Volta U, Antibodies to dietary antigens in coeliac disease. Scand J Gastroenterol 21(8), 935-940 (1986)
    Ciclitira PJ, Secretion of gliadin antibody by coeliac jejunal mucosal biopsies cultured in vitro. Clin Exp Immunol 64(1), 119-124 (1986)

    Kristen Campbell
    Celiac.com 10/02/2008 - Anyone with confirmed gluten sensitivity knows what a web of conflicting research and medical opinions he or she must wade through in order to get diagnosed. Sadly, it is a rare thing for a patient to have to consult less than a handful of doctors, and consider many various ailments before hearing the life-altering statement: You have celiac disease.
    So then it should be of no surprise that once the diagnosis has been made, there is still much debate over what this means to an individual. A celiac disease diagnosis means the lifetime avoidance of anything that contains gluten contained in wheat, barley and rye and their derivatives—and even this simple statement is not always agreed upon by experts.
    The consensus is that people with celiac disease or gluten intolerance must avoid the proteins found in wheat, barley and rye for the rest of their lives. But still, there is the occasional "expert" who seems to think that this “problem” could go away—that it can be “cured.” Of course, this idea seems completely off base to most, but to the patient of a doctor who has guided that individual into the gluten-free light, it just may seem to make sense.
    And reading even further into the only scientifically accepted treatment—a lifetime avoidance of gluten from wheat, barley and rye—more questions can be raised, for example: Should individuals who are gluten sensitive also avoid topical skin care and cosmetic products that contain gluten?
    Much of the research available seems to agree that lipsticks and toothpastes ought to be gluten free, but that a topically applied product need not be. Although this is a widely-accepted opinion, it falls to pieces the moment one considers the basis behind the entire green beauty industry’s monumental success: What goes on the skin, goes into the body.
    According to The Good Housekeeping Institute up to 60% of a product applied to the skin can be absorbed into the bloodstream. So why then would any individual with gluten sensitivity be so firm in his or her resolve to avoid dietary gluten, yet allow it to seep into the body via topical application? To some the answer may be simple—because his or her doctor said so. The very same doctor who changed that person’s life, forever improving his patient’s health, may not necessarily agree that gluten, or harmful fractions of gluten like gliadin, could pass into the patient's body and cause harm.
    A fortunate few, however, see a doctor who is more forward-thinking in his or her treatment methods—doctors who may be more aware of the latest research on gluten sensitivity. One example of such a doctor is Dr. Kenneth Fine, M.D. of EnteroLab.com, who understands that: "Gluten sensitivity is a systemic immune reaction to gluten anywhere in the body, not just that entering the body via the gut. Therefore, topically applied lotions, creams, shampoos, etc. containing gluten would indeed provide a source of gluten to the body, and we therefore recommend all such products be discontinued for optimal health."
    So to those individuals whose doctors still insist that it is unnecessary to adhere to a gluten-free beauty routine, perhaps an inquiry into that doctor’s thoughts on the general absorption of topical products may shine a light on the basis behind their opinions. Celiac disease and gluten sensitivity are becoming better understood, and some experts believe that up to 15% of Americans may be affected by some form of gluten sensitivity. And just as all who are gluten-sensitive continue to pour through the latest articles in an effort to live the healthiest gluten-free lifestyle that they can, so too are our doctors who are doing their very best to keep up with the latest scientific findings concerning gluten sensitivity. The more studies and research that are done on this topic, the better it will be for everyone—but unless a doctor is a specialist in this field, the necessary information concerning the broad range of problems that gluten can cause in a sensitive individual may not reach him in time.
    Perhaps acceptance of the idea that topical gluten can also wreak havoc internally is just the next step in the world-wide education of the ill effects that gluten can have on some people. But for now, the choice of whether or not to avoid topically applied cosmetics and skin care products that contain gluten is, for those affected, a matter of whose opinion they’re going to trust: Specialists in the field of gluten sensitivity, or doctors who may not be up on the latest information on the effects of gluten sensitivity.


    Jefferson Adams
    Celiac.com 01/20/2012 - Candi Smithson says her 2-year-old son, Preston, has severe allergies that present him from eating certain breads and dairy items, among other things. Celiac disease prevents Preston from eating anything containing gluten, a protein found in wheat, rye and barley.
    Preston also is allergic to certain milk proteins, making things like butter and other dairy products hazardous to his health.
    Smithson claims that the local pizza Hut in Muskogee, Oklahoma discriminated against her by asking her and her son to leave the restaurant. Smithson told reporters that she was in Muskogee as part of a home-schooling group to see replicas of the Niña and Pinta ships, which had been cruising the Arkansas River in recent weeks. Smithson, another parent and four children, including Preston, stopped at Pizza Hut to have lunch.
    Smithson told reporters from NewsOk.com that, before going into Pizza Hut, she had first stopped at McDonald's to get Preston a hamburger without the bun, and some french fries, which is safe for Preston to eat.
    She brought that food with her into Pizza Hut, where she planned to order pizza for the other kids. But before the group could place an order, Smithson said a waitress told her that she could not be in the store with the McDonald's items.
    Smithson told reporters that she explained the situation, but that the waitress remained unmoved.
    “I explained why I was bringing in the food, but she said it didn't matter,” Smithson said. Smithson then asked to speak to the manager. She says that the manager, who was reportedly unavailable for comment, was also unsympathetic to the situation.
    According to Smithson, the manager basically said, "We can't have this food in here, so we're going to have to ask you to leave,'” Smithson said. “I was really shocked ... we bring food into restaurants all the time, and this has never happened before.”
    Smithson told reporters that Pizza Hut had no signs indicating a no-outside-food policy, and added that the restaurant lost out on five paying customers by demanding the hamburger and fries be discarded.
    Indeed, a Pizza Hut official, who spoke to reporters on the condition he remain unnamed, says he knows of no company policies that would prevent paying customers from eating outside food in a Pizza Hut restaurant.
    According to reporters, calls to Pizza Hut's corporate offices seeking comment on this story went unreturned.
    Smithson says the actions of the Pizza Hut manager violated her son's rights as a person living with a disability. She claims food allergies that interfere with “major life activities” are considered disabilities.
    Marca Bristo, who helped craft the original Americans with Disabilities Act during the late 1980s, agrees with Smithson. Bristo served as chairman of the National Council on Disability, a position she was appointed to by former President Bill Clinton.
    Bristo said the Americans with Disabilities Act, enacted in 1990, was amended in 2008 to broaden what are considered “major life activities.” She said the changes were necessary because “the courts had narrowed the definition of the law” up to that point.
    Eating is listed as major life activity in the amended act, which went into effect Jan. 1, 2009.
    When asked about Candi Smithson's ordeal, Birsto said, “I do think she is right to challenge this." There are some ambiguities in the law, but, basically, Bristo says, "…if a food allergy affects life activities, it's got to be considered a disability and should fall under the act.”
    Still, Smithson insists she's not looking for money. “I just want the policies changed,” she told reporters. “That way, when he gets older, he won't have to deal with things like this.”
    Has anything like this happened to you or anyone you know?  Should restaurants be flexible when paying customers need to bring in outside food for reasons concerning allergies or food sensitivities? Let us know your thoughts.
    The story was originally reported by NewsOk.com.
    Source:

    http://newsok.com/oklahoma-mother-says-muskogee-pizza-hut-discriminated-against-son/article/3627995

    Jefferson Adams
    Celiac.com 09/30/2013 - The negative impact of celiac disease on the sexual health of celiac sufferers is one of the great undiscussed aspects of the disease, according to Phil Zimbardo, a prominent psychologist and professor emeritus at Stanford University in California.
    “No one talks about the sex part in celiac disease,” Zimbardo says, no one tells people that celiac disease can destroy their sex drive and challenge "their very manhood." This and other of Zimbardo's views on celiac disease and its impact on sexual health can be found in an excellent article by Lisa Fitterman in Allergicliving.com.
    For Zimbardo, life before his celiac diagnosis was a dark place. As his body suffered the effects of celiac disease, Zimbardo grew so depressed that he lost all interest in sex and intimacy. This, in turn, had a negative impact upon Zimbardo's marriage.
    This negative impact of celiac disease on sexual health is not unique to men. Many woman with celiac disease see their own sex lives suffer.
    In the case of Alice Bast, founder and president of the National Foundation for Celiac Awareness (NFCA), celiac disease had a number of adverse effects on her health and well-being.
    Bast acknowledges to Fetterman that symptoms of undiagnosed celiac disease pushed sex far from her mind, and that her libido did not make a miraculous return upon diagnosis and going gluten-free. Even after she was diagnosed, her physical recovery was slow, due to chronic malnourishment that contributed to multiple miscarriages and a stillbirth. In fact, when it came to sex, Bast says that the return of her sexual health came slowly, almost imperceptibly, until she realized that she was enjoying intimacy again after years of avoiding it.
    Echoing Bast's experience, Zimbardo points out that, "as a psychologist, I’m always analyzing behavior and I just couldn’t understand what has happening to me until I was diagnosed.”
    Once he was diagnosed, however, Zimbardo cut gluten from his diet and started taking anti-inflammatories and probiotics to regrow his gut flora. It took a full year for his gut to heal and for his full health and vigor to return, but now he is healthy, both physically and sexually.
    For Zimbardo, and many others, giving up the gluten is the key to returning to good health, and healthy sexual activity. Giving up gluten was "nothing short of transformative.” Now, he says he "can’t wait to be 80."
    There is a great deal of anecdotal information to suggest that celiac disease can have adverse impacts on sexual health, yet very little actual data exists. It will be interesting to see if and when researchers begin to look for answers. 

  • Recent Articles

    Jefferson Adams
    Celiac.com 04/20/2018 - A digital media company and a label data company are teaming up to help major manufacturers target, reach and convert their desired shoppers based on dietary needs, such as gluten-free diet. The deal could bring synergy in emerging markets such as the gluten-free and allergen-free markets, which represent major growth sectors in the global food industry. 
    Under the deal, personalized digital media company Catalina will be joining forces with Label Insight. Catalina uses consumer purchases data to target shoppers on a personal base, while Label Insight works with major companies like Kellogg, Betty Crocker, and Pepsi to provide insight on food label data to government, retailers, manufacturers and app developers.
    "Brands with very specific product benefits, gluten-free for example, require precise targeting to efficiently reach and convert their desired shoppers,” says Todd Morris, President of Catalina's Go-to-Market organization, adding that “Catalina offers the only purchase-based targeting solution with this capability.” 
    Label Insight’s clients include food and beverage giants such as Unilever, Ben & Jerry's, Lipton and Hellman’s. Label Insight technology has helped the Food and Drug Administration (FDA) build the sector’s very first scientifically accurate database of food ingredients, health attributes and claims.
    Morris says the joint partnership will allow Catalina to “enhance our dataset and further increase our ability to target shoppers who are currently buying - or have shown intent to buy - in these emerging categories,” including gluten-free, allergen-free, and other free-from foods.
    The deal will likely make for easier, more precise targeting of goods to consumers, and thus provide benefits for manufacturers and retailers looking to better serve their retail food customers, especially in specialty areas like gluten-free and allergen-free foods.
    Source:
    fdfworld.com

    Jefferson Adams
    Celiac.com 04/19/2018 - Previous genome and linkage studies indicate the existence of a new disease triggering mechanism that involves amino acid metabolism and nutrient sensing signaling pathways. In an effort to determine if amino acids might play a role in the development of celiac disease, a team of researchers recently set out to investigate if plasma amino acid levels differed among children with celiac disease compared with a control group.
     
    The research team included Åsa Torinsson Naluai, Ladan Saadat Vafa, Audur H. Gudjonsdottir, Henrik Arnell, Lars Browaldh, and Daniel Agardh. They are variously affiliated with the Institute of Biomedicine, Department of Microbiology & Immunology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; the Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; the Department of Pediatric Gastroenterology, Hepatology and Nutrition, Karolinska University Hospital and Division of Pediatrics, CLINTEC, Karolinska Institute, Stockholm, Sweden; the Department of Clinical Science and Education, Karolinska Institute, Sodersjukhuset, Stockholm, Sweden; the Department of Mathematical Sciences, Chalmers University of Technology, Gothenburg, Sweden; the Diabetes & Celiac Disease Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden; and with the Nathan S Kline Institute in the U.S.A.
    First, the team used liquid chromatography-tandem mass spectrometry (LC/MS) to analyze amino acid levels in fasting plasma samples from 141 children with celiac disease and 129 non-celiac disease controls. They then crafted a general linear model using age and experimental effects as covariates to compare amino acid levels between children with celiac disease and non-celiac control subjects.
    Compared with the control group, seven out of twenty-three children with celiac disease showed elevated levels of the the following amino acids: tryptophan; taurine; glutamic acid; proline; ornithine; alanine; and methionine.
    The significance of the individual amino acids do not survive multiple correction, however, multivariate analyses of the amino acid profile showed significantly altered amino acid levels in children with celiac disease overall and after correction for age, sex and experimental effects.
    This study shows that amino acids can influence inflammation and may play a role in the development of celiac disease.
    Source:
    PLoS One. 2018; 13(3): e0193764. doi: & 10.1371/journal.pone.0193764

    Jefferson Adams
    Celiac.com 04/18/2018 - To the relief of many bewildered passengers and crew, no more comfort turkeys, geese, possums or other questionable pets will be flying on Delta or United without meeting the airlines' strict new requirements for service animals.
    If you’ve flown anywhere lately, you may have seen them. People flying with their designated “emotional support” animals. We’re not talking genuine service animals, like seeing eye dogs, or hearing ear dogs, or even the Belgian Malinois that alerts its owner when there is gluten in food that may trigger her celiac disease.
    Now, to be honest, some of those animals in question do perform a genuine service for those who need emotional support dogs, like veterans with PTSD.
    However, many of these animals are not service animals at all. Many of these animals perform no actual service to their owners, and are nothing more than thinly disguised pets. Many lack proper training, and some have caused serious problems for the airlines and for other passengers.
    Now the major airlines are taking note and introducing stringent requirements for service animals.
    Delta was the first to strike. As reported by the New York Times on January 19: “Effective March 1, Delta, the second largest US airline by passenger traffic, said it will require passengers seeking to fly with pets to present additional documents outlining the passenger’s need for the animal and proof of its training and vaccinations, 48 hours prior to the flight.… This comes in response to what the carrier said was a 150 percent increase in service and support animals — pets, often dogs, that accompany people with disabilities — carried onboard since 2015.… Delta said that it flies some 700 service animals a day. Among them, customers have attempted to fly with comfort turkeys, gliding possums, snakes, spiders, and other unusual pets.”
    Fresh from an unsavory incident with an “emotional support” peacock incident, United Airlines has followed Delta’s lead and set stricter rules for emotional support animals. United’s rules also took effect March 1, 2018.
    So, to the relief of many bewildered passengers and crew, no more comfort turkeys, geese, possums or other questionable pets will be flying on Delta or United without meeting the airlines' strict new requirements for service and emotional support animals.
    Source:
    cnbc.com

    admin
    WHAT IS CELIAC DISEASE?
    Celiac disease is an autoimmune condition that affects around 1% of the population. People with celiac disease suffer an autoimmune reaction when they consume wheat, rye or barley. The immune reaction is triggered by certain proteins in the wheat, rye, or barley, and, left untreated, causes damage to the small, finger-like structures, called villi, that line the gut. The damage occurs as shortening and villous flattening in the lamina propria and crypt regions of the intestines. The damage to these villi then leads to numerous other issues that commonly plague people with untreated celiac disease, including poor nutritional uptake, fatigue, and myriad other problems.
    Celiac disease mostly affects people of Northern European descent, but recent studies show that it also affects large numbers of people in Italy, China, Iran, India, and numerous other places thought to have few or no cases.
    Celiac disease is most often uncovered because people experience symptoms that lead them to get tests for antibodies to gluten. If these tests are positive, then the people usually get biopsy confirmation of their celiac disease. Once they adopt a gluten-free diet, they usually see gut healing, and major improvements in their symptoms. 
    CLASSIC CELIAC DISEASE SYMPTOMS
    Symptoms of celiac disease can range from the classic features, such as diarrhea, upset stomach, bloating, gas, weight loss, and malnutrition, among others.
    LESS OBVIOUS SYMPTOMS
    Celiac disease can often less obvious symptoms, such fatigue, vitamin and nutrient deficiencies, anemia, to name a few. Often, these symptoms are regarded as less obvious because they are not gastrointestinal in nature. You got that right, it is not uncommon for people with celiac disease to have few or no gastrointestinal symptoms. That makes spotting and connecting these seemingly unrelated and unclear celiac symptoms so important.
    NO SYMPTOMS
    Currently, most people diagnosed with celiac disease do not show symptoms, but are diagnosed on the basis of referral for elevated risk factors. 

    CELIAC DISEASE VS. GLUTEN INTOLERANCE
    Gluten intolerance is a generic term for people who have some sort of sensitivity to gluten. These people may or may not have celiac disease. Researchers generally agree that there is a condition called non-celiac gluten sensitivity. That term has largely replaced the term gluten-intolerance. What’s the difference between celiac disease and non-celiac gluten-sensitivity? 
    CELIAC DISEASE VS. NON-CELIAC GLUTEN SENSITIVITY (NCGS)
    Gluten triggers symptoms and immune reactions in people with celiac disease. Gluten can also trigger symptoms in some people with NCGS, but the similarities largely end there.

    There are four main differences between celiac disease and non-celiac gluten sensitivity:
    No Hereditary Link in NCGS
    Researchers know for certain that genetic heredity plays a major role in celiac disease. If a first-degree relative has celiac disease, then you have a statistically higher risk of carrying genetic markers DQ2 and/or DQ8, and of developing celiac disease yourself. NCGS is not known to be hereditary. Some research has shown certain genetic associations, such as some NCGS patients, but there is no proof that NCGS is hereditary. No Connection with Celiac-related Disorders
    Unlike celiac disease, NCGS is so far not associated with malabsorption, nutritional deficiencies, or a higher risk of autoimmune disorders or intestinal malignancies. No Immunological or Serological Markers
    People with celiac disease nearly always test positive for antibodies to gluten proteins. Researchers have, as yet, identified no such antobodies or serologic markers for NCGS. That means that, unlike with celiac disease, there are no telltale screening tests that can point to NCGS. Absence of Celiac Disease or Wheat Allergy
    Doctors diagnose NCGS only by excluding both celiac disease, an IgE-mediated allergy to wheat, and by the noting ongoing adverse symptoms associated with gluten consumption. WHAT ABOUT IRRITABLE BOWEL SYNDROME (IBS) AND IRRITABLE BOWEL DISEASE (IBD)?
    IBS and IBD are usually diagnosed in part by ruling out celiac disease. Many patients with irritable bowel syndrome are sensitive to gluten. Many experience celiac disease-like symptoms in reaction to wheat. However, patients with IBS generally show no gut damage, and do not test positive for antibodies to gliadin and other proteins as do people with celiac disease. Some IBS patients also suffer from NCGS.

    To add more confusion, many cases of IBS are, in fact, celiac disease in disguise.

    That said, people with IBS generally react to more than just wheat. People with NCGS generally react to wheat and not to other things, but that’s not always the case. Doctors generally try to rule out celiac disease before making a diagnosis of IBS or NCGS. 
    Crohn’s Disease and celiac disease share many common symptoms, though causes are different.  In Crohn’s disease, the immune system can cause disruption anywhere along the gastrointestinal tract, and a diagnosis of Crohn’s disease typically requires more diagnostic testing than does a celiac diagnosis.  
    Crohn’s treatment consists of changes to diet and possible surgery.  Up to 10% of Crohn's patients can have both of conditions, which suggests a genetic connection, and researchers continue to examine that connection.
    Is There a Connection Between Celiac Disease, Non-Celiac Gluten Sensitivity and Irritable Bowel Syndrome? Large Number of Irritable Bowel Syndrome Patients Sensitive To Gluten Some IBD Patients also Suffer from Non-Celiac Gluten Sensitivity Many Cases of IBS and Fibromyalgia Actually Celiac Disease in Disguise CELIAC DISEASE DIAGNOSIS
    Diagnosis of celiac disease can be difficult. 

    Perhaps because celiac disease presents clinically in such a variety of ways, proper diagnosis often takes years. A positive serological test for antibodies against tissue transglutaminase is considered a very strong diagnostic indicator, and a duodenal biopsy revealing villous atrophy is still considered by many to be the diagnostic gold standard. 
    But this idea is being questioned; some think the biopsy is unnecessary in the face of clear serological tests and obvious symptoms. Also, researchers are developing accurate and reliable ways to test for celiac disease even when patients are already avoiding wheat. In the past, patients needed to be consuming wheat to get an accurate test result. 
    Celiac disease can have numerous vague, or confusing symptoms that can make diagnosis difficult.  Celiac disease is commonly misdiagnosed by doctors. Read a Personal Story About Celiac Disease Diagnosis from the Founder of Celiac.com Currently, testing and biopsy still form the cornerstone of celiac diagnosis.
    TESTING
    There are several serologic (blood) tests available that screen for celiac disease antibodies, but the most commonly used is called a tTG-IgA test. If blood test results suggest celiac disease, your physician will recommend a biopsy of your small intestine to confirm the diagnosis.
    Testing is fairly simple and involves screening the patients blood for antigliadin (AGA) and endomysium antibodies (EmA), and/or doing a biopsy on the areas of the intestines mentioned above, which is still the standard for a formal diagnosis. Also, it is now possible to test people for celiac disease without making them concume wheat products.

    BIOPSY
    Until recently, biopsy confirmation of a positive gluten antibody test was the gold standard for celiac diagnosis. It still is, but things are changing fairly quickly. Children can now be accurately diagnosed for celiac disease without biopsy. Diagnosis based on level of TGA-IgA 10-fold or more the ULN, a positive result from the EMA tests in a second blood sample, and the presence of at least 1 symptom could avoid risks and costs of endoscopy for more than half the children with celiac disease worldwide.

    WHY A GLUTEN-FREE DIET?
    Currently the only effective, medically approved treatment for celiac disease is a strict gluten-free diet. Following a gluten-free diet relieves symptoms, promotes gut healing, and prevents nearly all celiac-related complications. 
    A gluten-free diet means avoiding all products that contain wheat, rye and barley, or any of their derivatives. This is a difficult task as there are many hidden sources of gluten found in the ingredients of many processed foods. Still, with effort, most people with celiac disease manage to make the transition. The vast majority of celiac disease patients who follow a gluten-free diet see symptom relief and experience gut healing within two years.
    For these reasons, a gluten-free diet remains the only effective, medically proven treatment for celiac disease.
    WHAT ABOUT ENZYMES, VACCINES, ETC.?
    There is currently no enzyme or vaccine that can replace a gluten-free diet for people with celiac disease.
    There are enzyme supplements currently available, such as AN-PEP, Latiglutetenase, GluteGuard, and KumaMax, which may help to mitigate accidental gluten ingestion by celiacs. KumaMax, has been shown to survive the stomach, and to break down gluten in the small intestine. Latiglutenase, formerly known as ALV003, is an enzyme therapy designed to be taken with meals. GluteGuard has been shown to significantly protect celiac patients from the serious symptoms they would normally experience after gluten ingestion. There are other enzymes, including those based on papaya enzymes.

    Additionally, there are many celiac disease drugs, enzymes, and therapies in various stages of development by pharmaceutical companies, including at least one vaccine that has received financial backing. At some point in the not too distant future there will likely be new treatments available for those who seek an alternative to a lifelong gluten-free diet. 

    For now though, there are no products on the market that can take the place of a gluten-free diet. Any enzyme or other treatment for celiac disease is intended to be used in conjunction with a gluten-free diet, not as a replacement.

    ASSOCIATED DISEASES
    The most common disorders associated with celiac disease are thyroid disease and Type 1 Diabetes, however, celiac disease is associated with many other conditions, including but not limited to the following autoimmune conditions:
    Type 1 Diabetes Mellitus: 2.4-16.4% Multiple Sclerosis (MS): 11% Hashimoto’s thyroiditis: 4-6% Autoimmune hepatitis: 6-15% Addison disease: 6% Arthritis: 1.5-7.5% Sjögren’s syndrome: 2-15% Idiopathic dilated cardiomyopathy: 5.7% IgA Nephropathy (Berger’s Disease): 3.6% Other celiac co-morditities include:
    Crohn’s Disease; Inflammatory Bowel Disease Chronic Pancreatitis Down Syndrome Irritable Bowel Syndrome (IBS) Lupus Multiple Sclerosis Primary Biliary Cirrhosis Primary Sclerosing Cholangitis Psoriasis Rheumatoid Arthritis Scleroderma Turner Syndrome Ulcerative Colitis; Inflammatory Bowel Disease Williams Syndrome Cancers:
    Non-Hodgkin lymphoma (intestinal and extra-intestinal, T- and B-cell types) Small intestinal adenocarcinoma Esophageal carcinoma Papillary thyroid cancer Melanoma CELIAC DISEASE REFERENCES:
    Celiac Disease Center, Columbia University
    Gluten Intolerance Group
    National Institutes of Health
    U.S. National Library of Medicine
    Mayo Clinic
    University of Chicago Celiac Disease Center

    Jefferson Adams
    Celiac.com 04/17/2018 - Could the holy grail of gluten-free food lie in special strains of wheat that lack “bad glutens” that trigger the celiac disease, but include the “good glutens” that make bread and other products chewy, spongey and delicious? Such products would include all of the good things about wheat, but none of the bad things that might trigger celiac disease.
    A team of researchers in Spain is creating strains of wheat that lack the “bad glutens” that trigger the autoimmune disorder celiac disease. The team, based at the Institute for Sustainable Agriculture in Cordoba, Spain, is making use of the new and highly effective CRISPR gene editing to eliminate the majority of the gliadins in wheat.
    Gliadins are the gluten proteins that trigger the majority of symptoms for people with celiac disease.
    As part of their efforts, the team has conducted a small study on 20 people with “gluten sensitivity.” That study showed that test subjects can tolerate bread made with this special wheat, says team member Francisco Barro. However, the team has yet to publish the results.
    Clearly, more comprehensive testing would be needed to determine if such a product is safely tolerated by people with celiac disease. Still, with these efforts, along with efforts to develop vaccines, enzymes, and other treatments making steady progress, we are living in exciting times for people with celiac disease.
    It is entirely conceivable that in the not-so-distant future we will see safe, viable treatments for celiac disease that do not require a strict gluten-free diet.
    Read more at Digitaltrends.com , and at Newscientist.com