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      Frequently Asked Questions About Celiac Disease   04/24/2018

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What is Celiac Disease and the Gluten-Free Diet? What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes
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    BIOLINERX ANNOUNCES TRIAL OF NEW CELIAC DRUG


    Jefferson Adams

    Celiac.com 01/31/2014 - Drug company BioLineRx has announced trials of BL-7010, a drug for treating celiac disease. BL-7010 is a new, non-absorbable, orally available polymer with a high affinity for gliadins, the immunogenic proteins present in gluten that cause celiac disease.


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    Image: Public Media--BioLineRXBL-7010 is intended to treat celiac disease by sequestering and effectively masking gliadins from enzymatic degradation and preventing the formation of immunogenic peptides that trigger the classic adverse immune reaction.

    The BL-7010 is then excreted with gliadin from the digestive tract, preventing the absorption of gliadin into the blood.

    The overall effect is to significantly reduce the immune response triggered by gluten. According to BioLineRX, pre-clinical studies have shown BL-7010 to be both safety and effective.

    BioLineRX's Phase 1/2 study is a two-part, both single and repeated, double-blind, placebo-controlled, dose escalation study of BL-7010 in up to 32 patients.

    The main goal is to gauge the safety of single and repeated increasing doses of BL-7010 in well-controlled celiac disease patients.

    They also hope to assess the results of systemic exposure, if any, of BL-7010 in the study patients.

    Source:


    Image Caption: Image: Public Media--BioLineRX
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    Why in the world would I want to take a drug (which will definitely have side effects - they all do) to "treat" my celiac disease, when I have a proven, harmless, effective, inexpensive treatment already at my fingertips? I have no desire to EVER eat gluten again. I am perfectly happy being gluten free and I eat wholesome, delicious foods that nourish my body instead of destroying it. Recently, I was asked if I wanted to participate in clinical trials for a new "vaccine" for celiac disease. NO! Why would I take that kind of risk when I am already doing the best thing I can do for myself?

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    Guest Kristen

    Posted

    Why in the world would I want to take a drug (which will definitely have side effects - they all do) to "treat" my celiac disease, when I have a proven, harmless, effective, inexpensive treatment already at my fingertips? I have no desire to EVER eat gluten again. I am perfectly happy being gluten free and I eat wholesome, delicious foods that nourish my body instead of destroying it. Recently, I was asked if I wanted to participate in clinical trials for a new "vaccine" for celiac disease. NO! Why would I take that kind of risk when I am already doing the best thing I can do for myself?

    Why, you ask, Jacqie? Because this could change the lives of so many of us.

     

    I know, for myself, this would not change my overall eating habits. I too am (mostly) happy with my current diet. I eat very well also, and was never a big bread person. The biggest loss for me was the dairy, but I've made my peace with it.

     

    However, all that said I know there are a lot of people like me, who are so very limited in how they can function on a social level. For me, a cross-contamination event has a downtime of weeks to months. The pain and recovery are so intense and long lasting that eating out anywhere is simply not worth the risk. This is incredibly limiting. I cannot simply go out and order off the gluten free menu. There is no trust there. To get that freedom back, to be able to go (anywhere, vacations etc) with my spouse and not have to worry about how we are going to feed me, would be life changing. To order out and not worry about cross contamination. Amazing.

    Yes, there will likely be side effects, but until we know more, I would not completely discount the idea.

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    I have a very different opinion than Jacqie above. I spent the first 50 years of my life avoiding bread, pasta and such...anyway, I have no desire to ever eat that stuff again.

     

    But I long for a time I can just eat out with others without poring over every detail of a menu and interrogating waiters for ten minutes. Or get some occasional Chinese carry-out. Or travel without constant planning, worrying and a carry-on full of gluten-free food. Or just walk into any hole-in the wall ethnic restaurant and order something (obviously non-wheaty) I've never heard of, like I used to when I was a food blogger...

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    Guest Peggy Worley

    Posted

    Why in the world would I want to take a drug (which will definitely have side effects - they all do) to "treat" my celiac disease, when I have a proven, harmless, effective, inexpensive treatment already at my fingertips? I have no desire to EVER eat gluten again. I am perfectly happy being gluten free and I eat wholesome, delicious foods that nourish my body instead of destroying it. Recently, I was asked if I wanted to participate in clinical trials for a new "vaccine" for celiac disease. NO! Why would I take that kind of risk when I am already doing the best thing I can do for myself?

    I totally agree with you. When I first started "gluten free" it was really hard to do--now two years later I realize it's the way you are supposed to eat anyway!! Just go with fresh meat, fruits and veggies. I have kept my weight down to perfect for 2 years. I wouldn't change a thing.

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    Guest Heather

    Posted

    Why in the world would I want to take a drug (which will definitely have side effects - they all do) to "treat" my celiac disease, when I have a proven, harmless, effective, inexpensive treatment already at my fingertips? I have no desire to EVER eat gluten again. I am perfectly happy being gluten free and I eat wholesome, delicious foods that nourish my body instead of destroying it. Recently, I was asked if I wanted to participate in clinical trials for a new "vaccine" for celiac disease. NO! Why would I take that kind of risk when I am already doing the best thing I can do for myself?

    I wouldn't want to participate in a trial, either. But, if the drug is eventually proven safe and effective and could be taken to eliminate cross-contamination risks (like when eating out), I'm all for it!

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    Why in the world would I want to take a drug (which will definitely have side effects - they all do) to "treat" my celiac disease, when I have a proven, harmless, effective, inexpensive treatment already at my fingertips? I have no desire to EVER eat gluten again. I am perfectly happy being gluten free and I eat wholesome, delicious foods that nourish my body instead of destroying it. Recently, I was asked if I wanted to participate in clinical trials for a new "vaccine" for celiac disease. NO! Why would I take that kind of risk when I am already doing the best thing I can do for myself?

    Because the gluten free diet is much more expensive than a regular diet there are so many people around the world with not enough economic resources to achieve a complete gluten free diet.

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  • Related Articles

    Jefferson Adams
    Celiac.com 03/23/2011 - A group of researchers in India recently conducted a community-based study on the prevalence of celiac disease in the northern part of India.
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    The data showed an overall sero-prevalence of celiac disease was 1.44% (95% conï¬dence interval [CI] 1.22 1.69) and the overall prevalence of celiac disease was 1.04% (95% CI 0.85 1.25).
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    Source:

    Journal of Gastroenterology and Hepatology, March 2011 / DOI: 10.1111/j.1440-1746.2010.06606.x

    Jefferson Adams
    Celiac.com 03/28/2011 - While rates of diagnosed celiac disease are less than 1 in 2,000 in the United States, screening studies in European and other populations have shown a much higher prevalence.
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    The research team included Kent D. Katz MD, Shahrooz Rashtak MD, Brian D. Lahr BS, MS, L. Joseph Melton III MD, Patricia K. Krause BS, MBA, Kristine Maggi PA-C, Nicholas J. Talley MD, PhD, and Joseph A. Murray MD.
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    Source:

    Am J Gastroenterol advance online publication 1 March 2011. doi: 10.1038/ajg.2011.21

    Jefferson Adams
    Celiac.com 12/25/2013 - At present, the number of reported celiac disease cases is extremely low in China. 
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    Source:
    PLOS ONE DOI: 10.1371/journal.pone.0081151

    Jefferson Adams
    06/04/2014 - A Swedish research team study of nearly four decades of population-based data shows that rates of celiac disease are rising in most age groups of children.
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    Celiac disease risk varies between birth cohorts, which indicates environmental and/or lifestyle risk factors may be at play in triggering celiac disease. Finding new prevention strategies will require further research.
    Source:
    BMC Gastroenterology 2014, 14:59. doi:10.1186/1471-230X-14-59

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    Tammy Rhodes
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    Then, my second brush with a natural disaster happened, without any notice, leaving us once again scrambling to find a safe place to shelter. It was a warm and muggy summer morning, and my husband was away on a business trip leaving my young daughter and me to enjoy our summer day. Our Severe Weather Alert Radio was going off, again, as I continued getting our daughter ready for gymnastics.  Having gotten used to the (what seemed to be daily) “Severe Thunderstorm warning,” I didn’t pay much attention to it. I continued downstairs with my daughter and our dog, when I caught a glimpse out the window of an incredibly black looking cloud. By the time I got downstairs, I saw the cover to our grill literally shoot straight up into the air. Because we didn’t have a fenced in yard, I quickly ran outside and chased the cover, when subsequently, I saw my neighbor’s lawn furniture blow pass me. I quickly realized I made a big mistake going outside. As I ran back inside, I heard debris hitting the front of our home.  Our dog was the first one to the basement door! As we sat huddled in the dark corner of our basement, I was once again thinking where are we going to go if our house is destroyed. I was not prepared, and I should have been. I should have learned my lesson the first time. Once the storm passed, we quickly realized we were without power and most of our trees were destroyed. We were lucky that our house had minimal damage, but that wasn’t true for most of the area surrounding us.  We were without power for five days. We lost most of our food - our gluten free food.
    That is when I knew we had to be prepared. No more winging it. We couldn’t take a chance like that ever again. We were “lucky” one too many times. We were very fortunate that we did not lose our home to the Los Angeles wildfire, and only had minimal damage from the severe storm which hit our home in Illinois.
      
    In 2017 alone, FEMA (Federal Emergency Management Agency) had 137 natural disasters declared within the United States. According to FEMA, around 50% of the United States population isn’t prepared for a natural disaster. These disasters can happen anywhere, anytime and some without notice. It’s hard enough being a parent, let alone being a parent of a gluten free family member. Now, add a natural disaster on top of that. Are you prepared?
    You can find my Gluten Free Emergency Food Bags and other useful products at www.allergynavigator.com.  

    Jefferson Adams
    Celiac.com 04/23/2018 - A team of researchers recently set out to learn whether celiac disease patients commonly suffer cognitive impairment at the time they are diagnosed, and to compare their cognitive performance with non-celiac subjects with similar chronic symptoms and to a group of healthy control subjects.
    The research team included G Longarini, P Richly, MP Temprano, AF Costa, H Vázquez, ML Moreno, S Niveloni, P López, E Smecuol, R Mazure, A González, E Mauriño, and JC Bai. They are variously associated with the Small Bowel Section, Department of Medicine, Dr. C. Bonorino Udaondo Gastroenterology Hospital; Neurocience Cognitive and Traslational Institute (INECO), Favaloro Fundation, CONICET, Buenos Aires; the Brain Health Center (CESAL), Quilmes, Argentina; the Research Council, MSAL, CABA; and with the Research Institute, School of Medicine, Universidad del Salvador.
    The team enrolled fifty adults with symptoms and indications of celiac disease in a prospective cohort without regard to the final diagnosis.  At baseline, all individuals underwent cognitive functional and psychological evaluation. The team then compared celiac disease patients with subjects without celiac disease, and with healthy controls matched by sex, age, and education.
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    A total of thirty-three subjects were diagnosed with celiac disease. Compared with the 26 healthy control subjects, the 17 celiac disease subjects, and the 17 disease control subjects, who mostly had irritable bowel syndrome, showed impaired cognitive performance (P=0.02 and P=0.04, respectively), functional impairment (P<0.01), and higher depression (P<0.01). 
    From their data, the team noted that any abnormal cognitive functions they saw in adults with newly diagnosed celiac disease did not seem not to be a result of the disease itself. 
    Their results indicate that cognitive dysfunction in celiac patients could be related to long-term symptoms from chronic disease, in general.
    Source:
    J Clin Gastroenterol. 2018 Mar 1. doi: 10.1097/MCG.0000000000001018.

    Connie Sarros
    Celiac.com 04/21/2018 - Dear Friends and Readers,
    I have been writing articles for Scott Adams since the 2002 Summer Issue of the Scott-Free Press. The Scott-Free Press evolved into the Journal of Gluten Sensitivity. I felt honored when Scott asked me ten years ago to contribute to his quarterly journal and it's been a privilege to write articles for his publication ever since.
    Due to personal health reasons and restrictions, I find that I need to retire. My husband and I can no longer travel the country speaking at conferences and to support groups (which we dearly loved to do) nor can I commit to writing more books, articles, or menus. Consequently, I will no longer be contributing articles to the Journal of Gluten Sensitivity. 
    My following books will still be available at Amazon.com:
    Gluten-free Cooking for Dummies Student's Vegetarian Cookbook for Dummies Wheat-free Gluten-free Dessert Cookbook Wheat-free Gluten-free Reduced Calorie Cookbook Wheat-free Gluten-free Cookbook for Kids and Busy Adults (revised version) My first book was published in 1996. My journey since then has been incredible. I have met so many in the celiac community and I feel blessed to be able to call you friends. Many of you have told me that I helped to change your life – let me assure you that your kind words, your phone calls, your thoughtful notes, and your feedback throughout the years have had a vital impact on my life, too. Thank you for all of your support through these years.