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    Jefferson Adams
    Celiac.com 06/03/2015 - Although dietary gluten is the trigger for celiac disease, risk is strongly influenced by genetic variation in the major histocompatibility complex (MHC) region.
    A team of researchers recently set out to fine map the MHC association signal to identify additional celiac disease risk factors independent of the HLA-DQA1 and HLA-DQB1 alleles. The researchers...

    Jefferson Adams
    Celiac.com 09/16/2015 - Autoimmune disease, such as type 1 diabetes, Crohn's disease, and juvenile idiopathic arthritis, affect about 7 to 10 percent of the population in the Western Hemisphere.
    Using genome-wide association studies (GWASs), researchers have identified hundreds of susceptibility genes, including shared associations across clinically distinct autoimmune diseases...

    Jefferson Adams
    Celiac.com 04/11/2016 - Growing evidence suggests that long noncoding RNAs (lncRNAs) play an important role in gene expression, especially that which influences inflammation. For example, researchers recently found that one lncRNA, lnc13, suppresses inflammatory gene expression in macrophages by interacting with proteins that regulate chromatin accessibility.
    Reduced levels...

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