Celiac.com Sponsor (A1):

Join eNewsletter

Celiac.com Sponsor (A1-m):

Join eNewsletter
  • Join Our Community!

    Ask us a question in our celiac / gluten-free forum.

  • Scott Adams

    Signs of Quality of Life Improvements in Kids with Celiac Disease during the COVID-19 Lockdown

    Scott Adams
    Reviewed and edited by a celiac disease expert.

      Kids with celiac disease could be a bit better off during Covid, according to a new study.

    Image: CC BY 2.0-- LibrarianYarns
    Caption: Image: CC BY 2.0-- LibrarianYarns

    Celiac.com 08/06/2020 - The global pandemic of Covid, caused by coronavirus SARS-CoV2, has caused serious damage to public health and the economy. However, some of the greatest effects may be mental and emotional. Pandemic response measures have necessitated restrictions on medical visits and treatments for non-Covid conditions. The results could include lack of regular follow-up care, or the delay in consulting a doctor about ongoing symptoms, all of which can degrade a patient's quality of life.

    Researchers just don't know much about how the lockdown is affecting the quality of life in patients with chronic diseases, like celiac disease, and Functional Gastrointestinal Disorders (FGDIs), especially in kids. The cause of FGIDs remains unknown, though most researchers favor a biopsychosocial explanation, in which biological and psychosocial processes drive the development of FGIDs. 

    Celiac.com Sponsor (A12):

    Celiac.com Sponsor (A12-m):

    A team of researchers recently set out to try to get an idea of the influence of the Covid pandemic on the mental health and wellbeing of patients, especially kids, with chronic diseases. The research team included Francesca Fiori Nastro; Carlo Tolone; Maria Rosaria Serra; Daniela Pacella; Angelo Campanozzi; and Caterina Strisciuglio. They are variously affiliated with the University of Naples Federico II, Department of Pediatrics, Naples, Italy; the University of Campania ``Luigi Vanvitelli,'' Department of Woman, Child and General Specialistic Surgery, Naples, Italy; the University of Naples Federico II, Department of Public Health, Naples, Italy; and the University of Foggia, Department of Medical and Surgical sciences, Italy.

    A number of studies have shown that children with celiac disease, even on a gluten-free diet, have a higher risk for functional abdominal pain disorders, so there was some concern about how those kids might fare during Covid lockdown.

    For their study, the research team assessed gastrointestinal symptoms in celiac patients at the time of the diagnosis (T0), and rates of reported FGIDs after six months (T1) of gluten-free diet. They also compared rates of FGIDs between T1 and during the lockdown for COVID-19 (T2). Data supports the idea that psychological factors, such as stress or anxiety, may play a role in the development of FGDIs. 

    The team conducted an observational study on 71 children, aged 1 to 18 years, with clinically diagnosed celiac disease. The team also prospectively followed a group of gluten-free celiac children from the time of their diagnosis, between January 2018 and March 2019, through the study.

    During the Covid lockdown, the team interviewed patients by phone. Patients or their parents then completed the Rome IV, Peds QL 4.0 General Well-Being Scale and Promis anxiety surveys. 

    At T2, during the lockdown for COVID-19, the team found reduced rates of all FGIDs, compared to T1. They also found less constipation, and a decrease in post prandial distress syndrome.

    The median total score of the General Well-being scale was 80.13 showing good patient quality of life, in general. More than seventy percent of patients showed no anxiety, according to the Promis anxiety questionnaires. The researchers theorize that the improvement in symptoms, wellbeing and social functioning, may result from reduced exposure to stressful events, such as school, coupled with an increased parental closeness.

    The study results did show that a large number of children with gastrointestinal symptoms at the time of celiac diagnosis went on to develop FGIDs when they follow a gluten-free diet. The researchers suspect that this may be due to low grade inflammation, even with negative tests for serum tissue transglutaminase IGA antibody. They suspect that these levels may fall after a year on a gluten-free diet, as reflected in the decreased frequency of FGIDs observed after one year of GFD, compared to six months.

    Even though this is a small study, it's a rigorous one, with solid data. Italy has been hard hit by the Covid pandemic, and even a bit of good news about kids with celiac disease seeing some overall improvements in quality of life under Covid lockdown is welcome news. Hopefully our celiac children here in the U.S. are seeing similarly improvements under the Covid lockdown.

    Read more at: dldjournalonline.com

    Edited by Scott Adams


    User Feedback

    Recommended Comments

    Very interesting. I do believe stress always exacerbates many conditions. As an adult with gluten intolerance I think I also fared better during this lockdown. Though I had to work from home I was not rushed on mornings, my stress level was much lower and I could take my time and prepare my food. There were no flareups or reactions.

    Share this comment

    Link to comment
    Share on other sites

    Join the conversation

    You are posting as a guest. If you have an account, sign in now to post with your account.
    Note: Your post will require moderator approval before it will be visible.

    Add a comment...

    ×   Pasted as rich text.   Restore formatting

      Only 75 emoji are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.

  • About Me

    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):

    Celiac.com Sponsors (A17-m):

  • Related Articles

    Scott Adams
    Celiac.com 05/21/2020 - Currently more than 2.4 million people worldwide have contracted COVID-19, suffering symptoms ranging from fever and dry cough, to temporary loss of smell and taste, to extreme respiratory distress requiring oxygen, and even intubation. In many places, hospital resources have been taxed, as large numbers of people have sought medical help. Until recently, young people, especially children were thought to be generally safe from the virus and its effects. That has changed recently, as new information has come to the attention of doctors. In one recently finding, researchers noted that "three children in New York have died from a rare...

    Scott Adams
    Celiac.com 05/13/2019 - People with celiac and other diseases are being forced back to work by political leaders demanding that they sacrifice themselves and their loved ones to "help the economy."  The problem is not simply relegated to pressure from bosses. In fact, some state governors are threatening to end unemployment benefits, including the federal $600 weekly CARES unemployment benefit, for anyone who refuses to return to work, as requested by their employer.
    You can read about that in this related article, which is aptly subtitled, "Governors Cut Off New Unemployment Benefits Before Some People Even Got Checks."
    Of course, the ...

    Scott Adams
    Celiac.com 06/15/2020 - Usually, when a food manufacturer makes an ingredient change, even a minor one, to a food product, they must produce a new label for all the changed products. However, Covid-19 has changed that. Responding to calls from food manufacturers facing supply chain problems in the wake of the Covid-19 pandemic, the Food and Drug Administration (FDA) is relaxing some labeling requirements for certain ingredients in food in the U.S.
    The move will give food manufacturers the ability make small changes to the ingredients in a product without making label changes. That may mean adding, omitting, or blending ingredients to meet the product...

    Scott Adams
    Celiac.com 06/29/2020 - Coronavirus Disease 2019 (Covid-19) has killed nearly a half a million people globally, and over 120,000 here in the United States. People with celiac disease have to eat gluten-free in order to avoid negative health consequences.
    The pandemic fallout has included home lockdowns, food shortages, and disruptions. How concerned and/or anxious are people with celiac disease about the lockdowns and the possible shortages of gluten-free food?
    A team of researchers recently set out to to evaluate the perception of this in celiac disease patients who require a lifelong gluten-free diet as a therapy. The research team included ...