No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Positive Antigliadin Antibody (AGA) is a Poor Marker for Celiac Disease

Eur J Gastroenterol Hepatol 2006;18:503-506.

Celiac.com 08/14/2006 – A team of German researchers led by Dr. Martin W. Laass of the Childrens Hospital in Dresden have determined that antigliadin antibody (AGA) positivity disappears in over 50% of cases, and is therefore a poor marker for celiac disease. The researchers did follow up AGA testing on 69 adults and 47 children who participated in a much larger study conducted four years ago and found that only 26 of the adults and 21 of the children still had detectable levels of AGA in their blood samples, and none of them were positive for IgA-class anti-endomysial antibodies. Additionally no correlation was found in the subjects between their serum and fecal AGA.

Ads by Google:

The researchers conclude that the appearance of AGA should be interpreted as a non-specific “immunomodulation phenomenon” that has low specificity as a diagnostic marker for celiac disease. The researchers emphasize that it is still unknown why the AGA markers are transient, but various conditions might account for it, including a change in the sensitivity of the test that was used in the original study conducted four years ago versus the one used in this study.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


http://www.cghjournal.org/article/S1542-3565(16)30547-X/pdf

This is all so interesting. Thank you all for responding, you've helped me.

You could try removing all grain and dairy and see if that helps. Processed foods can have cross contamination. Lactose intolerance is common with celiac disease. Fruits are high in fructose and it can be difficult for some people to digest fructose if they have digestive problems. Vegetables a...

Yeah with the chocolate, I can attest that it really helps with ones mood, problem is most cocoa is processed and defatted, your best best are RAW cocoa from BigTree, Cocoa Nibs, or my personal favorite Crio Bru which is ground cocoa nibs that are meant as a coffee replacement >.> I eat them by t...

I don't know for sure but if you have a emotional roller coaster it may be do to food sensitivities. The pattern however may be difficult to figure out. I also removed all grains and milk from my diet. I limit my fruit and fructose consumption (fructose binds with tryptophan in the gut) and don...