No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Prevalence and Early Diagnosis of Celiac Disease in Autoimmune Thyroid Disorders

AUTHORS: Cuoco L; Certo M; Jorizzo RA; De Vitis I; Tursi A; Papa A; De Marinis L; Fedeli P; Fedeli G; Gasbarrini G
AUTHOR AFFILIATION: Department of Internal Medicine, Catholic University S.C., Rome, Italy.
SOURCE: Ital J Gastroenterol Hepatol 1999 May;31(4):283-7 [MEDLINE record in process]
CITATION IDS: PMID: 10425571 UI: 99354303

ABSTRACT: BACKGROUND AND AIMS - Celiac disease is associated with several autoimmune disorders such as insulin-dependent diabetes, Sjogrens syndrome, Addisons disease and thyroid diseases. The aim of our study was to evaluate the prevalence of celiac disease in patients affected by autoimmune thyroid diseases by means of anti-gliadin and anti-endomysial antibodies. PATIENTS: We studied 92 patients affected by autoimmune thyroid diseases (47 chronic autoimmune thyroiditis, 22 Hashimotos thyroiditis and 23 Graves disease). Ninety patients with non autoimmune thyroid disorders (51 multifollicular goitre, 28 solitary nodule and 11 papillary carcinoma) and 236 blood donors also took part in the study as control groups. METHODS: Total serum IgA were measured in all subjects to exclude selective IgA deficiency; then we measured anti-gliadin antibodies and anti-endomysial antibodies. In patients with anti-gliadin/anti-endomysial antibody positivity and/or with haematinic and laboratory signs of malabsorption we carried out gastrointestinal endoscopy with duodenal histological examination.

Ads by Google:

RESULTS: Among the 92 patients with autoimmune thyroid disease, 4 (4.3%) showed anti-gliadin and anti-endomysial positivity and had celiac disease; among the 90 patients with non autoimmune thyroid diseases, 1 (1.1%) had celiac disease; finally, among the blood donors, 1 subject (0.4%) was anti-gliadin-anti-endomysium antibody positive and had celiac disease. Those subjects presenting with only anti-gliadin antibody positivity did not have celiac disease.

CONCLUSIONS: These results show that the prevalence of celiac disease in patients with autoimmune thyroid diseases is significantly increased when compared with the general population (p = 0.009) but not with patients affected by non autoimmune thyroid disorders (p = 0.18). We suggest a serological screening for celiac disease in all patients with autoimmune thyroid disease measuring anti-endomysial antibodies, considering that early detection and treatment of celiac disease are effective in preventing its complications.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



1 Response:

 
Kathy Tappe
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
15 Jun 2009 6:31:00 PM PST
Good Job!




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Ummm what does this have to do with our gluten free community? Good point about giving stuff you would need to the community and all....but has nothing to do with celiac disease really, just mentions you should not give gluten free bread to a homeless persons that does not need it stating that it...

In Austin, Wildwood Bakehouse and Wilder Wood Restaurant are totally gluten free. I had the chicken fried steak and gravy and onion rings!!! Awesome!!!

If you yourself have Celiac's disease, you probably shouldn't give gluten-free sandwiches to the homeless, because they're disgusting. Your male neighbor doesn't need tampons. That sort of reasoning should be applied. But you must always remember that the Gospel requires you to treat other people...

Hi there I have this exact same thing.. however I don?t have celiac that I know of.. I found this when google searching for what the heck is wrong with my face. I was wondering if you ever found out.. or if it just went away. Thanks

I have read the newbie 101 and have been careful about reading labels. I'm the only one that's gluten free in my household, so they could be contaminating me. I was eating gluten for 6 weeks after my blood test because it took that long to get an official diagnosis and my GP told me to still be e...