No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Study Shows High Instance of Polyneuropathy in Patients with Celiac Disease

Celiac.com 06/08/2007 -The results of a study recently published in the Alimentary Pharmacology & Therapeutics indicates that patients with celiac disease face a significant risk of polyneuropathy.

Faced with inconclusive evidence of past studies linking celiac disease to various neurological conditions, doctors J. F. Ludvigsson, T. Olsson, A. Akbom, and S.M. Montgomery, set out to provide more conclusive evidence regarding the association between celiac disease and several neurological diseases. They used Cox regression to examine the risk of neurological disorders in 14,000 people who were diagnosed with celiac disease between 1964 and 2003. These patients were compared with 70,000 reference individuals matched for age, sex, calendar year and county.

Celiac disease was associated with later polyneuropathy at a hazard ratio (HR) of 3.4; [95% CI = 2.3–5.1]. Results also showed prior polyneuropathy to be associated with subsequent celiac disease with an odds ratio of 5.4; [95% CI = 3.6–8.2). However, they found no statistically significant association between celiac disease and subsequent Huntingtons disease, hereditary ataxia, multiple sclerosis, myasthenia gravis, Parkinsons disease, or symptom ataxia.

Ads by Google:

The actual study results are as follows:
(HR = 0.9; 95% CI = 0.3–2.3), Parkinsons disease (HR = 1.2; 95% CI = 0.8–1.9), Alzheimers disease (HR = 1.5; 95% CI = 0.9–2.6), hereditary ataxia (HR = 1.3; 95% CI = 0.5–3.6), the symptom ataxia (HR = 1.9; 95% CI = 0.6–6.2), Huntingtons disease (HR = 1.7; 95% CI = 0.3–8.6), myasthenia gravis (HR = 0.8; 95% CI = 0.2–3.8) or spinal muscular atrophy.

Doctors Recommend Regular Celiac Disease Screening for People with Polyneuropathy

Because the connections between celiac disease and polyneuropathy indicate shared risks the doctors suggest that people with polyneuropathy undergo regular screening for celiac disease.

health writer who lives in San Francisco and is a frequent author of articles for Celiac.com.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



1 Response:

 
Rebecca Paul
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
21 May 2012 1:07:30 PM PST
I was stunned when I read this article and I need more information. I was diagnosed with celiac disease 15 years ago and have progressively had painful problems with my legs and keeping a sense of balance. My neurologist has diagnosed me with "axonal polyneuropathy". The doctors seem puzzled, as I do not have diabetes. Now what???




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Thank you so so much.

OMG Thank you so much!!! If it?s ok my email is sara.crowe@bstamerica.com i have no problem posting it - if you email me that would be great! thank you! sara

Absolutely. I'll see if the admins can give you my contact info so I don't have to post it. BTW, I'm still active duty and was deployed to Afghanistan last year for 9 months.

Hertzya last was here in 2011. But I sent a message to see if they will come back and respond.

You are replying to a 7 year old post, so I doubt you will hear back.